Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv – use these links below to get to the section you want:

Developmental biology

• Patterning & signalling
• Morphogenesis & mechanics
• Genes & genomes
• Stem cells, regeneration & disease modelling
• Plant development
• Evo-devo

Cell Biology

Modelling

Tools & Resources

Research practice and education

Developmental biology

| Patterning & signalling

Cooperation between Nodal and FGF signals regulates zebrafish cardiac cell migration and heart morphogenesis

Vanessa Gonzalez, Meagan G. Grant, Makoto Suzuki, Briana Christophers, Jessica Rowland Williams, Rebecca D. Burdine

MUM, a maternal unknown message, inhibits early establishment of the medio-lateral axis in the embryo of the kelp Saccharina latissima

Samuel Boscq, Bernard Billoud, Ioannis Theodorou, Tanweer Joemmanbaks, Bénédicte Charrier

Maternal gut Bifidobacterium breve modifies fetal brain metabolism in mice

Jorge Lopez-Tello, Raymond Kiu, Zoe Schofield, Douwe van Sinderen, Gwénaëlle Le Gall, Lindsay J Hall, Amanda N Sferruzzi-Perri

Wnt target gene Ascl4 is dispensable for skin appendage development

Verdiana Papagno, Ana-Marija Sulic, Jyoti Prabha Satta, Aida Kaffash Hoshiar, Vinod Kumar, Jukka Jernvall, Marja L. Mikkola

Notch Inhibition Enhances Morphological Reprogramming of microRNA-Induced Human Neurons

Kyle F Burbach, Andrew Yoo

The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

James W. Truman, Lynn M. Riddiford, Barbora Konopová, Marcela Nouzova, Fernando G. Noriega, Michelle Herko

ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

Eman Hijaze, Tsvia Gildor, Ronald Seidel, Majed Layous, Mark Winter, Luca Bertinetti, Yael Politi, Smadar Ben-Tabou de-Leon

Glycolysis-Wnt signaling axis tunes developmental timing of embryo segmentation

Hidenobu Miyazawa, Jona Rada, Paul Gerald Layague Sanchez, Emilia Esposito, Daria Bunina, Charles Girardot, Judith Zaugg, Alexander Aulehla

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in the mouse

Robin Kruger, Tristan Frum, A. Sophie Brumm, Stephanie L Hickey, Kathy Niakan, Farina Aziz, Marcelio Shammami, Jada Roberts, Amy Ralston

The deubiquitylating enzyme Fat Facets modulates Fat signalling and regulates tissue growth

Lauren E. Dawson, Alexander D. Fulford, Aashika Sekar, Paulo S. Ribeiro

Expression patterns of FGF and BMP pathway genes in the tardigrade Hypsibius exemplaris

Kira L. Heikes, Bob Goldstein

Soma-to-germline BMP signal is essential for Drosophila spermiogenesis

Emma Kristine Beard, Rachael P Norris, Miki Furusho, Mark Terasaki, Mayu Inaba

| Morphogenesis & mechanics

Cell density couples tissue mechanics to control the elongation speed of the body axis

Changqing Lu, Joana M. N. Vidigueira, Christopher Chan Jin Jie, Alicja Maksymiuk, Fengzhu Xiong

Sox9 links biliary maturation to branching morphogenesis

Hannah R Hrncir, Sergei Bombin, Brianna Goodloe, Connor B Hogan, Othmane Jadi, Adam D Gracz

Morphological deficits of glial cells in a transgenic mouse model for developmental stuttering

Afuh Adeck, Marissa Millwater, Camryn Bragg, Ruli Zhang, Shahriar SheikhBahaei

Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

Amandine Jarysta, Abigail L.D. Tadenev, Matthew Day, Barry Krawchuk, Benjamin E. Low, Michael V. Wiles, Basile Tarchini

Tcf12 controls dynamic calvarial bone growth and motor learning in mice

Takahiko Yamada, Jesse Anderson-Ramirez, Lu Gao, Peng Chen, Mingyi Zhang, Tingwei Guo, Jifan Feng, Thach-Vu Ho, Ivetta Vorobyova, Naomi Santa Maria, Russell Jacobs, Jian-Fu Chen, Yang Chai

Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans

Karin C Kiontke, R. Antonio Herrera, D. Adam Mason, Yash Patel, Stephanie Vernooy, Alyssa Woronik, David H.A. Fitch

Differential tissue deformability underlies shape divergence of the embryonic brain and spinal cord under fluid pressure

Susannah B. P. McLaren, Shi-Lei Xue, Siyuan Ding, Alex Winkel, Oscar Baldwin, Shreya Dwarakacherla, Kristian Franze, Edouard Hannezo, Fengzhu Xiong

Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

Sachin N Davis, Samuel H Grindel, John M Viola, Grace Y Liu, Jiageng Liu, Grace Qian, Catherine M Porter, Alex James Hughes

Dyrk1a is required for craniofacial development in Xenopus laevis.

Amanda J.G. Dickinson, Stacey E Wahl, Larisa Litovchick, Fatmata Sesay, H Katherin Johnson

Morphologically defined substages of tail morphogenesis in C. elegans males

Karin Kiontke, Porfirio Fernandez, Alyssa Woronik, David H. A. Fitch

Apical cell expansion maintained by Dusky-like establishes a scaffold for corneal lens morphogenesis

Neha Ghosh, Jessica E. Treisman

VEGF counteracts shear stress-determined arterial fate specification during capillary remodeling.

Dongying Chen, Oleksii S Rukhlenko, Brian G Coon, Divyesh Joshi, Raja Chakraborty, Kathleen A Martin, Boris N Kholodenko, Martin A Schwartz, Michael Simons

Underlying molecular effects to behavioral consequences present line of evidence for zebrafish eye development and function alteration by crude oil exposure.

Leonie Katharina Mueller, Sarah Johann, Bernd Denecke, Ali T Abdallah, Markus Hecker, Henner Hollert, Thomas-Benjamin Seiler

Etiology of Craniofacial and Cardiac Malformations in a Mouse Model of SF3B4-Related Syndromes

Shruti Kumar, Eric Bareke, Jimmy Lee, Emma Carlson, Fjodor Merkuri, Evelyn E. Schwager, Steven Maglio, Jennifer L. Fish, Jacek Majewski, Loydie A Jerome-Majewska

Coordination of cell cycle and morphogenesis during organ formation

Jeffrey Matthew, Vishakha Vishwakarma, Thao Phuong Le, Ryan A. Agsunod, SeYeon Chung

| Genes & genomes

Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice

Longjie Sun, Zheng Lv, Xuexue Chen, Rong Ye, Shuang Tian, Chaofan Wang, Xiaomei Xie, Lu Yan, Xiaohong Yao, Yujing Shao, Sheng Cui, Juan Chen, Jiali Liu

Essential Function of Transmembrane Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development

Zhimin Xu, Zhao Wang, Lifang Wang, Yingchuan B. Qi

Obox4 promotes zygotic genome activation upon loss of Dux

Youjia Guo, Tomohiro Kitano, Kimiko Inoue, Kensaku Murano, Michiko Hirose, Ten D. Li, Akihiko Sakashita, Hirotsugu Ishizu, Narumi Ogonuki, Shogo Matoba, Masayuki Sato, Atsuo Ogura, Haruhiko Siomi

ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

Debashish U. Menon, Prabuddha Chakraborty, Noel Murcia, Terry Magnuson

Emx2 is an essential regulator of ciliated cell development across embryonic tissues

Thanh Khoa Nguyen, John-Michael Rodriguez, Hannah M. Wesselman, Rebecca A. Wingert

Tolerance thresholds underlie responses to DNA damage during germline development

Gloria Jansen, Daniel Gebert, Tharini Ravindra Kumar, Emily Simmons, Sarah Murphy, Felipe Karam Teixeira

A Genetic Screen for regulators of CNS morphology in Drosophila

Haluk Lacin, Yuqing Zhu, Jose DiPaola, Beth A. Wilson, Yi Zhu, James B. Skeath

NEUROG2 regulates a human-specific neurodevelopmental gene regulatory program

Vorapin Chinchalongporn, Lakshmy Vasan, Fermisk Saleh, Dawn Zinyk, Hussein Ghazale, Ana-Maria Oproescu, Shruti Patel, Matthew Rozak, Yutaka Amemiya, Sisu Han, Alexandra Moffat, Sandra E Black, JoAnne McLaurin, Jamie Near, Arun Seth, Maged Goubran, Orly Reiner, Satoshi Okawa, Carol Schuurmans

Epigenetic priming of embryonic lineages in the mammalian epiblast

Miquel Sendra, Katie McDole, Daniel Jimenez-Carretero, Juan de Dios Hourcade, Susana Temiño, Morena Raiola, Léo Guignard, Philipp J Keller, Fátima Sánchez-Cabo, Jorge N. Domínguez, Miguel Torres

The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development.

Sung Eun Kim, Hyun Yi Kim, Bogdan Jan Wlodarczyk, Richard H Finnell

FoxO transcription factors actuate the formative pluripotency specific gene expression programme

Laura Santini, Saskia Kowald, Giovanni Sestini, Nicolas C Rivron, Martin Leeb

Targeted CRISPR-Cas9 screening identifies transcription factor network controlling murine haemato-endothelial fate commitment

Michael Teske, Tobias Wertheimer, Stefan Butz, Pascale Zwicky, Izaskun Mallona, Ulrich Elling, Christophe Lancrin, Burkhard Becher, Ana Rita Grosso, Tuncay Baubec, Nina Schmolka

A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates

Kwantae Kim, Katarzyna M. Piekarz, Alberto Stolfi

A spatiotemporally resolved atlas of mRNA decay in the C. elegans embryo reveals differential regulation of mRNA stability across stages and cell types

Felicia Peng, C Erik Nordgren, John Isaac Murray

Multiple intersecting pathways are involved in the phosphorylation of CPEB1 to activate translation during mouse oocyte meiosis

Chisato Kunitomi, Mayra Romero, Enrico Maria Daldello, Karen Schindler, Marco Conti

Wnt signaling alters CTCF binding patterns and global chromatin structure

Anna Nordin, Chaitali Chakraborty, Mattias Jonasson, Orgena Dano, Gianluca Zambanini, Pierfrancesco Pagella, Silvia Remeseiro, Claudio Cantù

CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development

Emily A. Bulger, Todd C. McDevitt, Benoit G. Bruneau

A microRNA that controls the emergence of embryonic movement

Jonathan A. C. Menzies, Andre M. Chagas, Claudio R. Alonso

Depot-Specific mRNA Expression Programs in Human Adipocytes Suggest Physiological Specialization via Distinct Developmental Programs

Heather J. Clemons, Daniel J. Hogan, Patrick O. Brown

The influence of early moderate prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study

Mitchell Bestry, Alexander N. Larcombe, Nina Kresoje, Emily K Chivers, Chloe Bakker, James P Fitzpatrick, Elizabeth J Elliott, Jeffrey M Craig, Evelyne Muggli, Jane Halliday, Delyse Hutchinson, Sam Buckberry, Ryan Lister, Martyn Symons, David Martino

HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

Fengmei Xu, Ritsuko Suyama, Toshifumi Inada, Shinichi Kawaguchi, Toshie Kai

Genetic and bioinformatic analyses reveal transcriptional networks underlying dual genomic coordination of mitochondrial biogenesis

Fan Zhang, Annie Lee, Anna Freitas, Jake Herb, Zongheng Wang, Snigdha Gupta, Zhe Chen, Hong Xu

Cell cycle length regulates heterochromatin reprogramming during early development in non-mammalian vertebrates

Hiroto S Fukushima, Takafumi Ikeda, Shinra Ikeda, Hiroyuki Takeda

| Stem cells, regeneration & disease modelling

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pluripotent Stem Cell

Samhan Alsolami, Arun Pandian Chandrasekaran, Yiqing Jin, Ismail M. Shakir, Yingzi Zhang, Gerardo Ramos-Mandujano, Baolei Yuan, Alfonso Saera-Vila, Juan Carlos Izpisua Belmonte, Mo Li

An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

Renée Moerkens, Joram Mooiweer, Aarón D. Ramírez-Sánchez, Roy Oelen, Lude Franke, Cisca Wijmenga, Robert J. Barrett, Iris H. Jonkers, Sebo Withoff

Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injuryv

Steven M. Garcia, Justin Lau, Agustin Diaz, Hannah Chi, Miguel Lizarraga, Aboubacar Wague, Cristhian Montenegro, Michael R. Davies, Xuhui Liu, Brian T. Feeley

All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency

Bruce Hayward, Daman Kumari, Clara D.M. van Karnebeek, André B.P. van Kuilenburg, Karen Usdin

Graft of cardiac progenitors in a pig model of right ventricular failure triggers myocardial epimorphosis, regeneration and protection of function

V Lambert, A Deleris, F Tibourtine, V Fouilloux, A Martin, P Bridge, E Aries, D Benoist, M Pucéat

Altered Extracellular Matrix Structure and Elevated Stiffness in a Brain Organoid Model for Disease

Maayan Karlinski Zur, Bidisha Bhattacharya, Sivan Ben Dror, Inna Solomonov, Alon Savidor, Tamar Sapir, Talia Harris, Tsviya Olender, Irit Sagi, Rita Schmidt, J. M. Schwarz, Amnon Buxboim, Orly Reiner

Integrative analysis of Hydra head regeneration reveals actions of conserved signaling pathways and transposable elements

Aide Macias-Muñoz, Lisa Y. Mesrop, Heidi Yahan Liang, Ali Mortazavi

Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis

Franziska Peters, Susanne Brodesser, Kai Kruse, Hannes C.A. Drexler, Jiali Hu, Dominika Lukas, Esther von Stebut, Martin Krönke, Carien M. Niessen, Sara A. Wickström

Generation of Systemic Chimeras via Rabbit Induced Pluripotent Stem Cells Reprogrammed with KLF2, ERAS, and PRMT6

Florence Perold, Hong-Thu Pham, Yannicke Pijoff, Nathalie Doerflinger, Sylvie Rival-Gervier, Anaïs Moulin, Luc Jouneau, Bertrand Pain, Thierry Joly, Véronique Duranthon, Marielle Afanassieff, Pierre Savatier, Nathalie Beaujean

Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish

Laura Massoz, David Bergemann, Arnaud Lavergne, Celia Reynders, Caroline Desiront, Chiara Goossens, Lydie Flasse, Bernard Peers, Marianne Voz, Isabelle Manfroid

The disruption of CtBP regulates DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells

Kota Sugiyama, Kazuma Yoshioka, Nao Hayakawa, Miyu Marutani, Ryo Masuda, Selma Alamanda Abadi, Yoshiyuki Seki

A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a mediator in the production of hematopoietic progenitors in vitro

Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Mike Shipston, Nicola Romano, Lesley Forrester, Pablo Menendez, Antonella Fidanza

Generation of natural killer and myeloid cells in a 3D artificial marrow organoid system

Bérénice Schell, Lin-Pierre Zhao, Camille Kergaravat, Emilie Lereclus, Maria Kalogeraki, Pierre Fenaux, Lionel Ades, Antoine Toubert, Marion Espeli, Karl Balabanian, Emmanuel Clave, Nicolas Dulphy, Valeria Bisio

Impaired skeletal muscle regeneration induced by Cre recombinase activation in skeletal muscle stem cells

Anita Kneppers, Audrey Saugues, Carole Dabadie, Sabrina Ben Larbi, Rémi Mounier

Hypoxia impacts small intestinal organoid stemness and differentiation

Xi Lan, Ping Qiu, Chunfeng Mou

Substrate elasticity does not impact on DNA methylation changes during differentiation of pluripotent stem cells

Mohamed H. Elsafi Mabrouk, Kira Zeevaert, Ann-Christine Henneke, Catharina Maaßen, Wolfgang Wagner

A robust and inducible precise genome editing via an all-in-one prime editor in human pluripotent stem cells

Youjun Wu, Aaron Zhong, Mega Sidharta, Tae Wan Kim, Bernny Ramirez, Benjamin Persily, Lorenz Studer, Ting Zhou

Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

Katsuyuki Nishi, Taro Sakamaki, Akiomi Nagasaka, Kevin S. Kao, Kay Sadaoka, Masahide Asano, Nobuyuki Yamamoto, Akifumi Takaori-Kondo, Masanori Miyanishi

Neutrophil immune profile controls spinal cord regeneration in zebrafish

Carmen de Sena-Tomás, Leonor Rebola Lameira, Patrícia Naique Taborda, Alexandre Laborde, Michael Orger, Sofia de Oliveira, Leonor Saúde

Visualization of DNA Methylation in Cell Cycle Genes during iPSC Cardiac Differentiation

Ning Li, Ba Thong Nguyen, Zhenhe Zhang, Yiqiang Zhang

Application of Elevated Atmospheric Pressure and Hypoxia Enhance Pluripotency and Stem Cell Differentiation

Zachary Pappalardo, Bryan Downie, Bruce A. Adams, James Lim

OCT4 is expressed in extraembryonic endoderm stem (XEN) cell progenitors during somatic cell reprogramming

Alexandra Moauro, Stephanie L. Hickey, Michael A. Halbisen, Anthony Parenti, Amy Ralston

Differential growth and transcriptomic profile of stem cell-derived midbrain astrocytes

Zongze Li, Lucia Fernandez Cardo, Michal Rokicki, Jimena Monzón-Sandoval, Viola Volpato, Frank Wessely, Caleb Webber, Meng Li

Med12 cooperates with multiple differentiation signals to enhance embryonic stem cell plasticity

Max Fernkorn, Christian Schröter

Alterations of genomic imprinting appear during the reprogramming of adult neural stem cells

Raquel Montalban-Loro, Anna Lozano-Urena, Laura Lazaro-Carot, Esteban Jimenez-Villalba, Jordi Planells, Adela Lleches-Padilla, Mitsu Ito, Elisabeth Radford, Sacri M Ferron

Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids

Yuan Guan, Zhuoqing Fang, Angelina Hu, Sarah Roberts, Meiyue Wang, Patrik K. Johansson, Sarah C. Heilshorn, Annika Enejder, Gary Peltz

Patient derived model of UBA5-associated encephalopathy identifies defects in neurodevelopment and highlights potential therapies

Helen Chen, Yong-Dong Wang, Aidan W. Blan, Edith P. Almanza-Fuerte, Emily S. Bonkowski, Richa Bajpai, Shondra M. Pruett-Miller, Heather C. Mefford

Transgenic porcine model reveals two distinct LGR5-positive cell populations during lung development and homeostasis

Kathryn M. Polkoff, Nithin K. Gupta, Yanet Murphy, Ross Lampe, Jaewook Chung, Amber Carter, Jeremy M. Simon, Katherine Gleason, Adele Moatti, Preetish K. Murthy, Laura Edwards, Alon Greenbaum, Aleksandra Tata, Purushothama Rao Tata, Jorge A. Piedrahita

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

Emily Delgouffe, Samuel Madureira Silva, Frédéric Chalmel, Wilfried Cools, Camille Raets, Kelly Tilleman, Guy T’Sjoen, Yoni Baert, Ellen Goossens

Harnessing the regenerative potential of interleukin11 to enhance heart repair

Kwangdeok Shin, Anjelica Rodriguez-Parks, Yu Xia, Chenyang Dong, Sunduz Kelles, Jingli Cao, Junsu Kang

Human stem cell model of neural crest cell differentiation reveals a requirement of SF3B4 in survival, maintenance, and differentiation

Casey Griffin, Jean-Pierre Saint-Jeannet

A β-catenin:MSI2 axis regulates the expression of LEF1 and subsequent human haematopoietic stem/progenitor cell proliferation

Rhys G Morgan, Megan Wagstaff, Diu T Nguyen, Allison Blair, Benjamin P Towler, Sarah F Newbury

Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

Uxia Gurriaran-Rodriguez, Kasun Kodippili, David Datzkiw, Ehsan Javandoost, Fan Xiao, Maria Teresa Rejas, Michael A Rudnicki

| Plant development

Conserved auxin signalling synergism through the canonical and ETT-mediated pathways promotes gynoecium development in members of the Brassicaceae

Heather Marie McLaughlin, Tian-Feng Lü, Bhavani Natarajan, Lars Østergaard, Yang Dong

Unraveling wheat endosperm development: epigenetic regulation and novel regulators for enhanced yield and quality

Long Zhao, Jinchao Chen, Zhaoheng Zhang, Wenying Wu, Xuelei Lin, Mingxiang Gao, Yiman Yang, Peng Zhao, Yingyin Yao, Aiming Zhang, Dongcheng Liu, Dongzhi Wang, Jun Xiao

Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1

Devang Mehta, Sabine Scandola, Curtis Kennedy, Christina Lummer, Maria Camila Rodriguez Gallo, Lauren E. Grubb, Maryalle Tan, Enrico Scarpella, R. Glen Uhrig

A temporal map of division, chromatin modification, and identity specification in the regenerating Arabidopsis root.

Ramin Rahni, Bruno Guillotin, Laura Rose Lee, Kenneth David Birnbaum

The mitochondrial orf117Sha gene desynchronizes pollen development and causes pollen abortion in the Arabidopsis Sha CMS

Noémie Dehaene, Clément Boussardon, Philippe Andrey, Delphine Charif, Dennis Brandt, Clémence Gilouppe Taillefer, Thomas Nietzel, Anthony Ricou, Matthieu Simon, Joseph Tran, Daniel Vezon, Christine Camilleri, Shin-ichi Arimura, Markus Schwarzländer, Françoise Budar

The endophytic fungus Serendipita indica alters auxin distribution in Arabidopsis thaliana roots through alteration of auxin transport and conjugation to promote plant growth

Adrián González Ortega-Villaizán, Eoghan King, Manish K. Patel, Marta-Marina Pérez- Alonso, Sandra S. Scholz, Hitoshi Sakakibara, Takatoshi Kiba, Mikiko Kojima, Yumiko Takebayashi, Patricio Ramos, Luis Morales-Quintana, Sarah Breitenbach, Ana Smolko, Branka Salopek-Sondi, Nataša Bauer, Jutta Ludwig-Müller, Anne Krapp, Ralf Oelmüller, Jesús Vicente-Carbajosa, Stephan Pollmann

Morphological and genetic analysis of inflorescence and flower development in hemp (Cannabis sativa L.)

Jiaqi Shi, Susanne Schilling, Rainer Melzer

Expression-based machine learning models for predicting plant tissue identity

Sourabh Palande, Jeremy Arsenault, Patricia Basurto-Lozada, Andrew Bleich, Brianna N. I. Brown, Sophia F. Buysse, Noelle A. Connors, Sikta Das Adhikari, Kara C. Dobson, Francisco Xavier Guerra-Castillo, Maria F. Guerrero-Carrillo, Sophia Harlow, Héctor Herrera-Orozco, Asia T. Hightower, Paulo Izquierdo, MacKenzie Jacobs, Nicholas A. Johnson, Wendy Leuenberger, Alessandro Lopez-Hernandez, Alicia Luckie-Duque, Camila Martínez-Avila, Eddy J. Mendoza-Galindo, David Plancarte, Jenny M. Schuster, Harry Shomer, Sidney C. Sitar, Anne K. Steensma, Joanne Elise Thomson, Damián Villaseñor-Amador, Robin Waterman, Brandon M. Webster, Madison Whyte, Sofía Zorilla-Azcué, Beronda L. Montgomery, Aman Y. Husbands, Arjun Krishnan, Sarah Percival, Elizabeth Munch, Robert VanBuren, Daniel H. Chitwood, Alejandra Rougon-Cardoso

Amphicarpic development in the emerging model organism Cardamine chenopodiifolia

Aurelia Emonet, Miguel Perez-Anton, Ulla Neumann, Sonja Dunemann, Bruno Huettel, Robert Koller, Angela Hay

| Evo-devo

Genomic signatures of the evolution of loss of egg yolk in parasitoid wasps

Xianxin Zhao, Yuanyuan Liu, Yi Yang, Chun He, Kevin C. Chan, Haiwei Lin, Qi Fang, Gongyin Ye, Xinhai Ye

Evo-devo dynamics of hominin brain size

Mauricio González-Forero

Ascidian embryonic cells with properties of neural-crest cells and neuromesodermal progenitors of vertebrates

Tasuku Ishida, Yutaka Satou

Development and patterning of a highly versatile visual system in spiders

Luis Baudouin Gonzalez, Anna Schoenauer, Amber Harper, Saad Arif, Daniel J Leite, Philip O. M. Steinhoff, Matthias Pechmann, Valeriia Telizhenko, Atal Pande, Carolin Kosiol, Alistair P McGregor, Lauren Sumner-Rooney

Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head

Anna Markos, Jan Kubovciak, Simona Mikula Mrstakova, Anna Zitova, Jan Paces, Simona Machacova, Zbynek Kozmik -Jr, Zbynek Kozmik, Iryna Kozmikova

Developmental tinkering of gene regulation facilitated super rapid adaptive radiation

Anna Duenser, Pooja Singh, Ehsan Pashay Ahi, Marija Durdevic, Sylvia Schaeffer, Wolfgang Gessl, Ole Seehausen, Christian Sturmbauer

Sexually discordant selection is associated with trait specific morphological changes and a complex genomic response

Tyler Audet, Joelle Krol, Katie Pelletier, Andrew D Stewart, Ian Dworkin

Variation in Neural Crest Development and Functional Divergence of sox10 Paralogs Contribute to Morphological Diversification in Cichlid Fishes

Aleksandra Marconi, Grégoire Vernaz, Achira Karunaratna, Maxon J Ngochera, Richard Durbin, M. Emília Santos

Cell Biology

Premature endocycling of Drosophila follicle cells causes pleiotropic defects in oogenesis

Hunter C. Herriage, Brian R. Calvi

Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors

Weihua Wang, Junqiao Xing, Xiqi Zhang, Hongni Liu, Haochen Jiang, Cheng Xu, Xue Zhao, Zhangfeng Hu

Dynamic cytoophidia during Drosophila late oogenesis

Shi-Qi Zhang, Ji-Long Liu

An inappropriate decline in ribosome levels drives a diverse set of neurodevelopmental disorders

Chunyang Ni, Leqian Yu, Barbara Vona, Dayea Park, Yulei Wei, Daniel A Schmitz, Yudong Wei, Yi Ding, Masahiro Sakurai, Emily Ballard, Yan Liu, Ashwani Kumar, Chao Xing, Hyung-Goo Kim, Cumhur Ekmekci, Ehsan Ghayoor Karimiani, Shima Imannezhad, Fatemeh Eghbal, Reza Shervin Badv, Eva Maria Christina Schwaibold, Mohammadreza Dehghani, Mohammad Yahya Vahidi Mehrjardi, Zahra Metanat, Hosein Eslamiyeh, Ebtissal Khouj, Saleh Mohammed Nasser Alhajj, Aziza Chedrawi, César Augusto Pinheiro Ferreira Alves, Henry Houlden, Michael Kruer, Fowzan S. Alkuraya, Can Cenik, Reza Maroofian, Jun Wu, Michael Buszczak

Discovery of a multipotent cell type from the term human placenta

Sangeetha Vadakke-Madathil, Bingyan Wang, Micayla Oniskey, Fumiko Dekio, Rachel Brody, Shari Gelber, Rhoda Sperling, Hina W. Chaudhry

Endoplasmic reticulum stress delays choroid development in the HCAR1 knock-out mouse

Monir Modaresinejad, Xiaojuan Yang, Mohammad Ali Mohammad Nezhady, Tang Zhu, Emmanuel Bajon, Xin Hou, Houda Tahiri, Pierre Hardy, Jose Carlos Rivera, Pierre Lachapelle, Sylvain Chemtob

Perturbing nuclear glycosylation in the mouse preimplantation embryo slows down embryonic growth

Sara Formichetti, Urvashi Chitnavis, Agnieszka Sadowska, Na Liu, Ana Boskovic, Matthieu Boulard

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

Joan Chang, Adam Pickard, Jeremy A. Herrera, Sarah O’Keefe, Matthew Hartshorn, Richa Garva, Anna Hoyle, Lewis Dingle, Cédric Zeltz, Jason Wong, Adam Reid, Rajamiyer V. Venkateswaran, Yinhui Lu, Patrick Caswell, Stephen High, Donald Gullberg, Karl E. Kadler

Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice

Alexandra V. Bruter, Ekaterina A. Varlamova, Nina I. Stavskaya, Zoia G. Antysheva, Vasily N. Manskikh, Anna V. Tvorogova, D. S. Korshunova, Alvina I. Khamidullina, Marina V. Utkina, Viktor P. Bogdanov, Alyona I. Nikiforova, Eugene A. Albert, Denis O. Maksimov, Jing Li, Mengqian Chen, Alexander A. Shtil, Igor B. Roninson, Vladislav A. Mogila, Yulia Y. Silaeva, Victor V. Tatarskiy

An important role for triglyceride in regulating spermatogenesis

Charlotte F Chao, Yanina-Yasmin Pesch, Huaxu Yu, Chenjingyi Wang, Maria J Aristizabal, Tao Huan, Guy Tanentzapf, Elizabeth Rideout

IDENTIFICATION OF AN EARLY SUBSET OF CEREBELLAR NUCLEI NEURONS IN MICE

Maryam Rahimi-Balaei, Shayan Amiri, Thomas Lamonerie, Sih-Rong Wu, Huda Y Zoghbi, G. Giacomo Consalez, Daniel Goldowitz, Hassan Marzban

Gap junction and amino acid import in somatic cells promote germ cell growth

Caroline Vachias, Camille Tourlonias, Louis Grelée, Nathalie Gueguen, Yoan Renaud, Parvathy Venugopal, Graziella Richard, Pierre Pouchin, Émilie Brasset, Vincent Mirouse

Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53

Abhishiktha Godthi, Sehee Min, Srijit Das, Johnny Cruz-Corchado, Andrew Deonarine, Kara Misel-Wuchter, Priya D. Issuree, Veena Prahlad

Turnover of RNA-binding Proteins and MicroRNAs by intrinsically disordered region-directed ZSWIM8 ubiquitin ligase during brain development

Jing Lei, Siming Zhong, Rong Fan, Xin Shu, Guan Wang, Jiansheng Guo, Shuting Xue, Luqian Zheng, Aiming Ren, Junfang Ji, Bing Yang, Shumin Duan, Zhiping Wang, Xing Guo

Hepatoblast iterative apicobasal polarization is regulated by extracellular matrix remodeling

Julien Delpierre, Jose Ignacio Valenzuela, Matthew Bovyn, Nuno Pimpao Martins, Lenka Belicova, Urska Repnik, Maarten Bebelman, Sarah Seifert, Pierre A Haas, Yannis L Kalaidzidis, Marino Zerial

Modelling

Discovery of Waddington’s developmental canals elucidates the embryogenesis stability in Caenorhabditis elegans

Jianguo Wang, Long Xiao, Zeqi Yao, Shanjun Deng, Jianrong Yang, Chung-I Wu, Zhuo Du, Xionglei He

An adaptive numerical method for multi-cellular simulations of organ development and disease

James M. Osborne

Modularity of the segmentation clock and morphogenesis

James E. Hammond, Ruth Baker, Berta Verd

A Clock and Wavefront Self-Organizing Model Recreates the Dynamics of Mouse Somitogenesis in-vivo and in-vitro

Julie Klepstad, Luciano Marcon

Occurrence of non-apical mitoses at the primitive streak, induced by relaxation of actomyosin and acceleration of the cell cycle, contributes to cell delamination during mouse gastrulation.

Evangeline Despin-Guitard, Steffen Plunder, Navrita Mathiah, ERIC THEVENEAU, Isabelle Migeotte

Somatic epigenetic drift during shoot branching: a cell lineage-based model

Yifan Chen, Agata Burian, Frank Johannes

Tools & Resources

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

Kseniya Petrova, Maksym Tretiakov, Aleksandr Kotov, Anne H. Monsoro-Burq, Leonid Peshkin

Fast and lightweight cell atlas approximations across organs and organisms

Ying Xu, Joanna Ahn, Fabio Zanini

Integrated analysis and systematic characterization of the regulatory network for human germline development

Yashi Gu, Jiayao Chen, Ziqi Wang, Zhekai Li, Xia Xiao, Qizhe Shao, Yitian Xiao, Wenyang Liu, Sisi Xie, Yaxuan Ye, Jin Jiang, Xiaoying Xiao, Ya Yu, Min Jin, Robert Young, Lei Hou, Di Chen

High-parametric protein maps reveal the spatial organization in early-developing human lung

Sanem Sariyar, Alexandros Sountoulidis, Jan Niklas Hansen, Sergio Marco Salas, Mariya Mardamshina, Anna Martinez Sacals, Frederic Ballllosera Navarro, Zaneta Andrusivova, Xiaofei Li, Paulo Czarnewski, Joakim Lundeberg, Sten Linnarsson, Mats Nilsson, Erik Sundstrom, Christos Samakovlis, Emma Lundberg, Burcu Ayoglu

A new genetically tractable non-vertebrate system to study complete camera-type eye regeneration

Alice Accorsi, Brenda Pardo, Eric Ross, Timothy J. Corbin, Melainia McClain, Kyle Weaver, Kym Delventhal, Jason A. Morrison, Mary Cathleen McKinney, Sean A. McKinney, Alejandro Sánchez Alvarado

Improved mRNA electroporation into immature oocytes to examine protein dynamics during development

Yuhkoh Satouh, Emiko Suzuki, Keisuke Sasaki, Ken Sato

A feather star is born: embryonic development and nervous system organization in the crinoid Antedon mediterranea

Silvia Mercurio, Giacomo Gattoni, Giorgio Scarí, Miriam Ascagni, Benedetta Barzaghi, Maurice R Elphick, Elia Benito-Gutièrrez, Roberta Pennati

PCP Auto Count: A Novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting

Kendra L. Stansak, Luke D. Baum, Sumana Ghosh, Punam Thapa, Vineel Vanga, Bradley J. Walters

Research practice & education

Effectiveness of a network Open House model to recruit trainees to post-baccalaureate STEM programs

Scott Takeo Aoki, Lindsay Lewellyn, Sarah Justice, Sarah Mordan-McCombs, Neetu Tewari, Jorge Cantu, Robert Seiser, Ahmed Lakhani, Jennifer R. Kowalski

Scientific civility and academic performance

Emma Camacho, Quigly Dragotakes, Isabella Hartshorn, Arturo Casadevall, Daniel L Buccino

Nationwide Inclusive Facilitator Training: Mindsets, Practices and Growth

Diane Codding, Alexandria H. Yen, Haley Lewis, Vanessa Johnson-Ojeda, Regina F. Frey, Sarah Chobot Hokanson, Bennett B. Goldberg

An Examination of the Use of Large Language Models to Aid Analysis of Textual Data

Robert H. Tai, Lillian R. Bentley, Xin Xia, Jason M. Sitt, Sarah C. Fankhauser, Ana M. Chicas-Mosier, Barnas G. Monteith

Phase 1 of the National Institutes of Health Preprint Pilot: Testing the viability of making preprints discoverable in PubMed Central and PubMed

Kathryn Funk, Teresa Zayas-Cabán, Jeffrey Beck

Limited Diffusion of Scientific Knowledge Forecasts Collapse

Donghyun Kang, Robert S. Danziger, Jalees Rehman, James A. Evans

Experts fail to reliably detect AI-generated histological data

Jan Hartung, Stefanie Reuter, Vera Anna Kulow, Michael Fähling, Cord Spreckelsen, Ralf Mrowka

More than a token photo: humanizing scientists enhances student engagement

Robin A Costello, Emily P Driessen, Melissa K Kjelvik, Elizabeth H Schultheis, Rachel M Youngblood, Ash T Zemenick, Marjorie G Weber, Cissy J Ballen

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