Research associate: lung development and disease

The Rawlins lab studies lung development and lung stem cells with a particular focus on using human organoid models to study cellular and molecular mechanisms controlling development and repair. We have recently developed a series of innovative human lung organoid models and accompanying CRISPR tools which will further enable the study of human lung disease.

This position is part of a Wellcome-funded highly collaborative UK-based project which brings together human geneticists, lung cell biologists and clinicians to define the genetics and cell biology underlying chronic human lung disease. The specific project will focus initially on the use of CRISPR tools to model human genetic variation in organoids. There will be excellent scope for innovation and direction-setting, focusing on the long-term aim of identifying and testing potential disease-modifying pathways.

You should be passionate about developmental/stem cell biology, be willing to tackle difficult problems and be able to develop novel experimental approaches to answer outstanding questions. While prior experience with organoid culture, CRISPR genome editing, flow cytometry and next-generation sequencing would be advantageous, an eagerness to learn and to exploit and develop innovative methods is the critical requirement. You will play a key role in a highly collaborative research programme, so a friendly and collegial attitude is crucial.

You should have a PhD in a relevant subject, or be close to completion of your degree.