The community site for and by
developmental and stem cell biologists

PhD position on Molecular mechanisms of muscle lineage reprogramming

Posted by , on 24 August 2017

Closing Date: 15 March 2021

The Division of Developmental Biology at the FAU Erlangen-Nürnberg, invites applications for a

 

PhD student position (Salary Scale E13 TV-L/65%) on

 

Molecular mechanisms of muscle lineage reprogramming

 

in the group of Dr. Christoph Schaub. The position will start at the earliest possible date and will be limited to three years with a possible extension.

 

The Schaub group is interested in the molecular mechanisms that regulate syncytial muscle cell lineage commitment, maintenance and plasticity using the Drosophila embryonic and adult musculature as a model. The PhD project will focus on the molecular mechanisms that guide a naturally occurring direct lineage reprogramming process during the metamorphosis of the Drosophila musculature. In particular, the project will define the molecular processes that initiate and execute the dedifferentiation of syncytial embryonic muscles into mononucleate myoblasts which in turn are reprogrammed into the progenitors of adult heart associated muscles (Schaub et al. 2015, Curr Biol (25), 488-494). The PhD student will use a broad spectrum of state of the art techniques ranging from genome editing to modern live imaging approaches to analyse these questions.

 

We are looking for a highly motivated candidate with experience in Drosophila genetics and/or cell and molecular biology. Experience in microscopic tissue dissections is an advantage but not a requirement. We offer an exciting project utilizing our combined expertise in muscle cell biology and Drosophila genetics in a well-equipped lab. The project is embedded in an interdisciplinary scientific landscape in association with the Muscle Research Center Erlangen (MURCE, http://www.murce.fau.de/) and the Optical Imaging Center Erlangen (OICE, http://www.oice.uni-erlangen.de/) and will have access to high end imaging microscopes (Confocal, Spinning disk and Light-sheet microscopy).

 

If you are interested in the position please send a cover letter stating your motivation, your curriculum vitae, copies of Bachelor/Masters certificate (or equivalent) and two letters of recommendation or contact information for two scientific references in a single PDF to christoph.schaub@fau.de.

 

Thumbs up (No Ratings Yet)
Loading...

Categories: Jobs

One thought on “PhD position on Molecular mechanisms of muscle lineage reprogramming”

Leave a Reply

Your email address will not be published. Required fields are marked *

Get involved

Create an account or log in to post your story on the Node.

Sign up for emails

Subscribe to our mailing lists.

Most-read posts in May

Do you have any news to share?

Our ‘Developing news’ posts celebrate the various achievements of the people in the developmental and stem cell biology community. Let us know if you would like to share some news.