Post Doctoral Associate in the Rieger Lab

The Rieger lab is searching for a postdoctoral scholar in the Biology Department at the University of Miami.
The postdoctoral scholar will be working on mechanisms of chemotherapy-induced peripheral neuropathy using primarily zebrafish as a model system. Chemotherapy-induced peripheral neuropathy is a side effect of chemotherapy that affects 60-70% of patients for which currently no cures exist. The Rieger lab has developed a zebrafish model with which to study the mechanisms underlying sensory axon degeneration due to one particular chemotherapeutic agent, paclitaxel. Studies in this model identified a target, MMP-13, which when inhibited alleviates neuropathy. The goal is to analyze the role of paclitaxel in MMP-13 dysregulation and axon degeneration. This project involves in vivo imaging of zebrafish. A second goal is to collaborate with medicinal chemists to develop new inhibitors and test them in zebrafish and rodents in preparation for clinical studies in collaboration with the University of Miami Medical School.

Requirements:

Candidates must have a Ph.D. in Biology, Neurobiology, or a related discipline, and experience in conducting research with zebrafish, molecular biology and confocal imaging. Other important qualifications are a background in statistical methods, strong work ethic and strong organizational and time management skills. Other qualifications include problem-solving skills, experience in manuscript writing, a track record of publications, and independent research experience. Knowledge of medicinal chemistry or drug development are preferred.

Apply online at:

https://umiami.wd1.myworkdayjobs.com/en-US/UMCareerStaff/job/Campus—Coral-Gables/Post-Doctoral-Associate_R100025704-1

Position # P100041395

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