Post-doctoral Fellow, Molecular Determinants of Glioma Initiation and Progression

Apply your developmental biology / molecular biology / neurobiology skills to the problem of brain cancer.

The lab of Dr. Jennifer Chan seeks to recruit a motivated postdoctoral fellow to investigate cell fate decisions during the process of brain tumour development and progression.  Research in the lab focuses on growth factor signalling and transcriptional regulation as determinants of neural precursor identity and fate. We use models that include patient-derived glioma cultures, xenografts, and engineered mouse models generated from in utero and postnatal electroporation to address our research questions.

The successful candidate will collaborate with investigators in bioinformatics to apply tools of genomics, epigenomics, and transcriptomics to further define key alterations during neoplastic transformation, and will collaborate with medicinal chemists to determine if identified alterations may be potential therapeutic targets. Early-stage postdocs (within 3 years of receiving PhD or equivalent) with experience in advanced immunohistochemistry, fluorescence microscopy, gene editing, and molecular biology; and/or experience in genomic approaches like RNA-seq, ChIP-seq, ATAC-seq will be preferentially considered.

The position is available immediately.

Other information

Located in Calgary, Alberta, Canada, the Chan Lab is part of the Charbonneau Cancer Institute at the University of Calgary’s Cumming School of Medicine. Within the Charbonneau Institute, we are part vibrant multidisciplinary research groups focused on childhood cancers and brain cancers. Calgary is a very livable and family-friendly city located less than an hour’s drive from the Canadian Rocky Mountains – a haven for outdoor enthusiasts.

Application details

Submit a brief letter of interest, your academic CV, and the names and contact information of at least three references.

Applications should be submitted as a single PDF file and sent as an email with the subject line “Post-Doctoral Fellowship, Glioma Biology” to: jawchan@ucalgary.ca

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