Closing Date: 15 March 2021
A Postdoctoral position is available in the Spagnoli lab. in the Centre for Stem Cell and Regenerative Medicine at King’s College, London. Our team uses interdisciplinary approaches to study pancreas development and stem cells. The candidate will be part of an exciting EU-funded FET-Open consortium aiming at bioengineering pancreatic tissue.
Developing therapies for pancreatic diseases, such as diabetes and pancreatic cancer, is hampered by a limited access to pancreatic tissue in vivo. Engineering three-dimensional (3D) tissue models, which accurately mimic the native organ, have great potential in biomedical applications, providing powerful platforms for studying tissue development and homeostasis and for modeling diseases. We have established a multi-disciplinary FET European consortium with the ambitious goal of developing an innovative bio-printing approach for generating pancreatic tissue. Tissues and organs comprise multiple cell types with specific biological functions that must be recapitulated in the printed tissue. We will biomimic developmental processes to fabricate 3D bio-printed pancreatic tissue units that allow sustained cell viability, expansion and functional differentiation ex vivo.
The Spagnoli lab. is coordinating the Consortium and will be primarily responsible for establishing a 3D-imaging and transcriptome atlas of pancreatic cells and defining cellular sources for engineering pancreatic tissue units. The candidate will be part of a young dynamic team and help in developing this ambitious research program. Moreover, the lab. is based at the Centre for Stem Cells & Regenerative Medicine (CSCRM) at King’s College London, which acts as the nucleus for a vibrant and collaborative stem cell research community, being an ideal environment for a successful postdoc experience.
Applicants should have a recent Ph.D. degree or M.D./Ph.D. degree. Candidates with experience in stem cell and developmental biology, confocal microscopy, image acquisition and analysis will be preferred. This position seeks a highly motivated individual with a strong interest in developmental biology.
The position is open starting from October 2018 but later entry dates are possible. The initial contract is for one year and can be renewed until a maximum of three years.
A CV and a statement of research interests along with names of 2 referees should be sent via e-mail to the address below.
Dr. Francesca M. Spagnoli, Centre for Stem Cell and Regenerative Medicine, KCL, London, UK
Pancreas, Imaging, 3D cell engineering, ex vivo disease model, ex vivo organogenesis