The Musculoskeletal Extracellular Matrix Laboratory (MEML) in the Department of Mechanical Engineering at the University of Colorado – Boulder is seeking an exceptionally creative postdoctoral researcher to investigate the mechanistic basis for how extracellular matrix (ECM) remodeling directs regeneration in mammals. The project is a collaborative effort using spiny mice, an emerging model for mammalian musculoskeletal regeneration developed in the Seifert Lab in the Department of Biology at the University of Kentucky. As such, the selected candidate will work with both groups, but will based at CU-Boulder. The selected candidate will be trained to leverage cutting edge imaging and proteomic tools employed in the MEML to label, isolate and visualize newly generated ECM. Using this methodology, in combination with in vitro and in vivo approaches in spiny mice and lab mice, the selected candidate will investigate how ECM production, composition and force generation regulate regenerative healing.
Ideal candidates will have a strong background in at least two of the following areas (and a drive to learn and master the others): biomechanics of soft tissues, developmental biology, 3D/4D visualization of biological tissues, protein engineering and quantitative bioinformatics. Successful applicants will initially join an NIH funded project. While this is a funded position, postdocs in the MEML are strongly encouraged to develop their own projects and external funding portfolios as a pathway toward independence. Salary follows NIH guidelines for postdoctoral researchers. Informal inquiries by email are strongly encouraged. For additional information visit: https://www.colorado.edu/mechanical/sarah-calve.
Review of applications will begin on a rolling basis and will continue until the position has been filled. Ideal start date is Fall 2019/Winter 2020. Candidates will have completed their Ph.D. prior to starting the position but need not have defended their dissertation prior to applying. Applicants should send a single pdf document to Sarah Calve (email@example.com) that includes their CV, names of three references, and a 1-2-page synopsis of their current research interests and how these complement our overall research program.
The Department of Mechanical Engineering at CU-Boulder houses a strong group of research labs interested in biomedical engineering, materials science, imaging, robotics and micro/nanoscale engineering. Together, these labs create a vibrant atmosphere to leverage engineering principles and tools to clarify unanswered questions in biology.
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