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Postdoctoral Training Fellow – Niakan Laboratory

Posted by , on 2 October 2019

Closing Date: 15 March 2021

Job title:          Postdoctoral Training Fellow

Location:         The Francis Crick Institute, Midland Road, London

Contract:         Fixed-term, 4 years, full time

Salary:             Competitive with benefits, subject to skills and experience

Vacancy ID:     12287

Short summary

Dr Niakan’s laboratory focuses on understanding the mechanisms of lineage specification in human embryos and the derivation of novel human stem cells. Details of research projects currently being undertaken can be seen at:

Research techniques used in the laboratory include: molecular biology, advanced microscopy and image quantification, human and mouse preimplantation embryo culture and micromanipulation, genome modification, genome-wide techniques including single-cell RNA-sequencing, multi-omics analysis and human embryonic and induced pluripotent stem cell derivation.

We seek candidates who are energetic, focused, motivated, productive and collaborative with a desire to work in a congenial, dynamic, and collaborative research environment. Good organisational, analytical, and communication skills are essential.

Project scope

The aim of the project is to characterise early lineage specification in human preimplantation embryos. We aim to generate reporter embryos to perform in vivo lineage tracing to elucidate developmental trajectories of individual cells. The project will explore a range of single cell, imaging and genome editing techniques to understand early lineage specification mechanisms in human embryos. This knowledge will provide fundamental insights into human biology.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute is world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

  • If you are interested in applying for this role, please apply via our website.
  • The closing date for applications is 01 November 2019 at 23:45.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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