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Pregenerate GmbH is hiring an Imaging Specialist and a Research technician in Vienna

Posted by , on 4 August 2020

Closing Date: 15 March 2021

Pregenerate GmbH is hiring in Vienna

#Biotechnology #Imaging #Arthritis research # Drug discovery # Vienna # Machine learning #Cell differentiation assay #Organ-on-a-chip #Biotechnology #Microfluidic #EVOS7000 #personalized medicine #Automation #Liquid Handling #cell biology #Molecularbiology

 

Pregenerate is a young startup based on the lively Vienna Biocenter Campus surrounded by 12 other start up companies. At Pregenerate we are revolutionizing arthritis treatment with our organ-on-a-chip platform. This technology will ultimately allow us to stratify patients into targeted treatment subgroups, and even to tell each clinical patient what the best treatment is for their specific arthritis needs directly. Our device is also poised to save pharmaceutical companies billions of dollars and improve the success rates of their drugs to market, partly because we can use human cells to replace animal testing in pharmaceutical research for arthritis treatments.

www.pregenerate.net

 

Relevant publications:

Rosser, J. et al. Microfluidic nutrient gradient-based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model. Mater Today Bio 4, 100023, doi:10.1016/j.mtbio.2019.100023 (2019).

 

Vinatier, C. & Guicheux, J. Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments. Ann Phys Rehabil Med 59, 139-144, doi:10.1016/j.rehab.2016.03.002 (2016).

 

Haltmayer, E. et al. Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis. PLoS One 14, e0214709, doi:10.1371/journal.pone.0214709 (2019).

Please send the application with CV, academic record and coverletter to faheem@pregenerate.net

 

Molecular Biologist – technician

 

Establishment of Gene expression analysis at Pregenerate. Your aim will be to establish robust pipeline for analyzing responses to various medications to indicate the best treatment for arthritis on an individual patient level. Future work will include automating the system using a liquid handler.

 

Your talents and abilities:

M. Sc. in Life Sciences

Strong expertise in molecular biology (RNA extraction, qPCRs, Immunohistochemistry,…)

Tissue Culture experience

Skills in Excel and R programming would be advantageous

Good organizational skills

Enthusiasm for personalized medicine

Preferred starting date is 1st September, 2020

Imaging specialist

Leading the development of image analysis section at Pregenerate using Organ-on a chip technology. Your aim will be to establish and automated image analysis system to visualize the response of various medication in a 3D microfluidic system.

 

Your talents and abilities:

PhD in Life Sciences (M Sc. considered)

Strong expertise in imaging and imaging analysis

Image J programming a significant advantage

Experience with Confocal imaging and EVOS 7000

Image automation experience

Experience with microfluidics would advantageous

Skills in Excel and R programming would be advantageous

Project management

Enthusiasm for personalized medicine

Preferred starting time is September / October 2020

Industry experience is preferred

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