Senior Laboratory Research Scientist at the Crick Institute

We are looking for a highly motivated Senior Laboratory Scientist to join the quantitative cell biology laboratory headed by Dr Silvia Santos. The lab is a new addition to The Francis Crick Institute in London and focuses on understanding control principles in cell decision-making. Current areas of research include understanding control of cell division and differentiation, using human embryonic stem cells as a model system. There is a strong focus on single cell analysis and live cell imaging approaches. The team is currently composed of three PhD students and two post-doctoral fellows.

For more information please see

https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/silvia-santos/

and quantcellbio.wordpress.com

THE CANDIDATE

The successful post holder is expected to drive his/her own research, help with lab management and training and support on-going research projects. The ideal candidate is likely to be an energetic, focused and productive individual with a desire to work on interesting biological problems in a collegial and collaborative work environment. Excellent time management and organisation skills are essential.

PROJECT SCOPE
The decision to divide is a fundamental cellular decision and the conserved networks that trigger cell division adapt and remodel in a variety of biological contexts including developmental transitions and malignancy. We have been exploring spatio-temporal control of cell division in mammalian cells and remodelling of cell cycle networks during developmental transitions, using embryonic stem cells as a model system.
Embryonic stem cells have the propensity to differentiate into the three germ layers. The switch between pluripotency and differentiation in these cells has been our paradigm of choice to understand how protein and gene networks decode cellular signals and thereby encode irreversible commitment to different cell fates.
The molecular basis of these decisions is of fundamental biological importance and have significant clinical applications.

Informal enquires can be sent to Silvia Santos at: silvia.santos@crick.ac.uk

If interested please apply here with a cover letter stating your background and motivation, CV and names of two referees.

https://jobs.crick.ac.uk/pls/corehrrecruit//erq_jobspec_version_4.display_form?p_company=1&p_internal_external=E&p_display_in_irish=N&p_applicant_no=&p_recruitment_id=006424&p_process_type=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y

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