the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by Andreas Prokop on October 27th, 2020
Application Deadline: 22 January 2021 Supervisors: Andreas Prokop, Matthew Ronshaugen, Karl Kadler Project details How to apply To develop remedial strategies for neurodegeneration in age and disease, we need to improve our understanding of the cell biology of neurons – in particular their axons. Axons are the cable-like, up-to-meter long processes of neurons that wire[…]
Posted by luxen on May 25th, 2020
The group of Chen Luxenburg at the Faculty of Medicine, Tel Aviv University, invites applications for a PhD student position. Our laboratory is looking for excellent and highly motivated PhD students to study the role of the actin cytoskeleton in skin development. Our goal is to understand how cytoskeleton derived signals regulate stem cell[…]
Posted by the Node Interviews on May 21st, 2018
Intrahepatic bile ducts (IHBDs) are epithelial tubular structures that transport bile from the liver to the intestine, but the molecules and mechanisms controlling IHBD morphogenesis have remained largely unclear. A a recent paper in Development reports an investigation into IHBD development and the role the tumour suppressor and cytoskeletal regulator Merlin plays in the process. We caught[…]
Posted by the Node Interviews on March 12th, 2018
Neuronal migration is critical for mammalian brain development. In many migrating neurons, the nucleus translocates from the trailing to the leading edge of the cell in a manner dependent on the actin and microtubule cytoskeletons, but how these cytoskeletons interact and their relative contribution to the forces that move the nucleus has remained unclear. This[…]
Posted by Shyi-Chyi on February 17th, 2018
The key results of our recent paper in Nature Cell Biology Cell polarization defines the spatial biological specificities in a cell. During the first cell cycle of a C. elegans zygote, its symmetry is broken by local remodeling of the cortical actomyosin network. This leads to a segregation of the dedicated polarity regulators, the PAR[…]
Posted by Andreas Prokop on October 17th, 2017
The University of Manchester, 2018/19 BBSRC DTP PhD Project Understanding tubulin regulation during neuronal development, ageing and degeneration Axons are slender, up-to-a-meter long, cable-like extensions of neurons which form the nerves and nerve tracts that wire our bodies and brain. These delicate cellular structures have to be maintained for an organism’s life time and are[…]
Posted by the Node Interviews on September 20th, 2017
Development often involves the asymmetric partitioning of cellular components to daughters, and this process is crucial for successful gametogenesis. Today’s paper, published in the current issue of Development, explores the cytoskeletal mechanisms of spermatogenesis in different nematode species. We met the multi-lab team behind the work, starting with Diane Shakes (The College of William and Mary in[…]
Posted by kjchalut on June 17th, 2014
Once upon a time, physicists got curious about the cytoskeleton. They characterised the cytoskeleton – using tools of soft matter, statistical and polymer physics – as a mesoscale material whose physical properties govern its dynamics. They showed that the cytoskeleton is an interconnected scaffold that, depending on the time scale, can behave like a shape-morphing[…]
Posted by andreas on April 9th, 2014
The “Nuit Blanche” in Paris. A city wide exposition of contemporary arts from dusk till dawn. Performances, light shows, dance, installations. Along the Canal Saint-Martin the visitors stroll from one exhibition to the next or sit down and take a break, chatting and drinking. A bit further up Boulevard Avenue Richerand the south-west entrance to[…]
