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developmental and stem cell biologists
Posted by the Node Interviews, on 4 October 2017
Checkpoints ensure that mouse oocytes with DNA damage arrest in meiosis I, preventing non-viable embryo formation, however the mechanisms which activate this checkpoint have so far eluded researchers. This week ...Posted by DMDD, on 8 August 2017
Deciphering the Mechanisms of Developmental Disorders (DMDD) is a large-scale imaging and phenotyping programme for genetically modified mouse embryos. For embryos at E14.5, the key imaging technique is High Resolution ...Posted by DMDD, on 20 July 2017
A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of ...Posted by Alana Mendelsohn, on 24 February 2017
Comment on “Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles” Neuron 93, 1–14, February 22, 2017. Alana I. Mendelsohn, Departments of Neuroscience and Biochemistry ...Posted by DMDD, on 21 February 2017
A new paper published in Journal of Anatomy shows that measuring the amount of inter-digital webbing in mouse embryos between 14 and 15 days gestation is the best way to find ...Posted by DMDD, on 1 December 2016
This post originally appeared on Annotations, the DMDD blog. New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made ...Posted by Gregg Duester, on 25 October 2016
Postdoctoral Position open at: Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California An NIH-funded postdoctoral position is available to investigate the signaling functions of retinoic acid (RA) during ...Posted by DMDD, on 4 October 2016
This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a ...Posted by DMDD, on 29 September 2016
This article was originally posted on the DMDD website dmdd.org.uk Knowing the ‘normal’ expression of genes during embryo development is key to understanding the differences that occur due to genetic ...Posted by Natalie Butterfield, on 28 September 2016
ROLE of THYROID HORMONE in MOUSE INTESTINAL DEVELOPMENT and REGENERATION. Thyroid hormone (T3) is known to be critical for postembryonic development in mammals (around birth). This laboratory has been taking a multi-faceted approach ...