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Postdoctoral Position (development biology/ cell biology) m/w/d

Posted by on January 16th, 2020

The Department of Systemic Cell Biology (Prof. Dr. Bastiaens) at the Max Planck Institute for Molecular Physiology in Dortmund is offering a postdoctoral position (developmental biology/cell biology) to work in an interdisciplinary team of cell biologists and physicists studying mechanisms of tumorigenesis in intestinal organoids. We are investigating fundamental mechanisms of oncoprotein induced tumor development by[…]

Stowers Research Conferences: Developmental Cell Biology

Posted by on September 12th, 2019

SRC DevBio Poster http://www.stowers.org/conferences Stowers Research Conferences are biennial meetings that bring together researchers, faculty, and graduate students to inspire creative thought and collaboration in the basic sciences. The Developmental Cell Biology meeting will include 11 speakers with 13 talks chosen from abstracts, 2 poster sessions and a conference party to close the meeting. April 22-24,[…]

Embryonic development inspires regenerative medicine

Posted by on November 27th, 2017

The European Molecular Biology Lab (EMBL) in Barcelona and IRB Barcelona bring together leading scientists in the conference “Morphogenetic Engineering”, an event supported by the BBVA Foundation. The merge of various disciplines of developmental biology is key to enhancing our knowledge of tissue development and repair, processes that find their most direct applications in regenerative[…]

The people behind the papers – David Turner & Peter Baillie-Johnson

Posted by on November 6th, 2017

Embryonic patterning is dependent on the establishment of the anteroposterior (AP) and dorsoventral axes early in development. In mammals this occurs by a breaking of symmetry in the epiblast, however the molecular mechanisms controlling this process are still not fully understood. This week we feature a paper published in the latest issue of Development that[…]

The people behind the papers: Holly Voges, Enzo Porrello & James Hudson

Posted by on March 15th, 2017

The use of organoids – which can be defined as artificially grown masses of cells or tissue that resemble organs – in basic and clinical research has snowballed in recent years, providing insight into fundamental developmental processes and disease etiology. Today’s paper comes from the new Special Issue of Development devoted entirely to organoids, and reports the use of human[…]

YEN does it again

Posted by on June 29th, 2016

Last month saw the return of the Young Embryologist Network annual meeting held this year at the UCL Institute of Child Health. To settle into the long weekend, a number of us from the Briscoe Lab at the Crick Mill Hill site headed on down to central London to spend the day being inspired by[…]

Question of the month- brain organoids

Posted by on March 21st, 2016

Last week, Development announced a special issue on organoids. In vitro organogenesis is a burgeoning new field, with applications in the study of human development, drug testing and ultimately the possibility of producing functional organs in the dish that could be used for transplantation. Every new technological advance brings with it a new set of ethical issues, and[…]

Special Issue on Organoids

Posted by on March 15th, 2016

In vitro organogenesis has exploded onto the stem cell and developmental biology scene. It is now possible to make  miniaturised approximations of many different organs – known as organoids – entirely in vitro, using either pluripotent stem cells or adult tissue stem cells as starting material. Coaxed towards their fate by various signalling molecules and growth factors,[…]

An interview with Melissa Little

Posted by on March 15th, 2016

This interview first appeared in Development.   Melissa Little is a Senior Principal Research Fellow at the Murdoch Childrens Research Institute in Melbourne, Australia. Her lab has studied kidney development and regeneration for over 20 years, recently making notable advances in the generation of kidney organoids from human iPSCs. We chatted with Melissa about her career,[…]

Editorial- Closing the circle: from organoids back to development

Posted by on March 15th, 2016

This editorial was written by Melissa Little and first appeared in Development.   Organogenesis is an inherently fascinating developmental process. It requires the creation of complex form and function from a collection of distinct cell types, all of which come together without a template. To achieve this, cells within the developing organ undergo differentiation, migration,[…]