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Posted by jingyi, on 20 July 2016
Fertilization marks the start of life. This is followed by highly coordinated epigenetic reprogramming that allows protamine-histone exchange, zygotic genome activation, and the generation of a totipotent embryo. However, the ...Posted by Abcam Events, on 13 July 2016
Stem cells have the unique properties of both self renewal and differentiation into various lineages. In the last few years, chromatin architecture and noncoding RNAs are emerging as major players in both gene ...Posted by cdemers, on 5 July 2016
Unraveling Development Embryonic development is a complex and regulated spatiotemporal ensemble of signaling cues that control cell differentiation. Most of what we now know comes from experimenting directly on embryos. ...Posted by Elizabeth Rideout, on 27 May 2016
Bruno Hudry and Elizabeth J. Rideout Male and female fruit flies differ in many aspects of development and physiology. For example, males and females differ in abdominal pigmentation, sex comb ...Posted by Disease Models and Mechanisms, on 4 May 2016
This post highlights the approach and findings of a new research article published in Disease Models & Mechanisms: ‘Stem cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila’. This ...Posted by the Node, on 18 March 2016
Here is some developmental biology related content from other journals published by The Company of Biologists. Drosophila as a model to study human disease The latest ...Posted by Caroline Hendry, on 15 March 2016
In vitro organogenesis has exploded onto the stem cell and developmental biology scene. It is now possible to make miniaturised approximations of many different organs – known as organoids – entirely ...Posted by the Node, on 15 March 2016
This interview first appeared in Development. Melissa Little is a Senior Principal Research Fellow at the Murdoch Childrens Research Institute in Melbourne, Australia. Her lab has studied kidney development ...Posted by Katherine Brown, on 15 March 2016
This editorial was written by Melissa Little and first appeared in Development. Organogenesis is an inherently fascinating developmental process. It requires the creation of complex form and function from ...Posted by Caroline Hendry, on 14 March 2016
It’s been 10 years since induced pluripotent stem cells (iPSCs) were first reported from the lab of Prof. Shinya Yamanaka. Since then, the field of direct reprogramming has grown immensely, ...