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two postdoc positions at UCL, London

Posted by , on 20 June 2016

Closing Date: 15 March 2021

Epithelial Cell and Developmental Biology – Mechanotransduction at tight junctions

Applications are invited for the posts of two postdoctoral research fellows. One will be based in the Laboratory for Epithelial Cell Biology (with Karl Matter and Maria Balda) of the UCL Institute of Ophthalmology and the other in the Zebrafish Group of the Department of Cell & Developmental Biology (with Masazumi Tada).

The successful applicants will join a collaborative research programme that focuses on the role of mechanotransduction at epithelial tight junctions in epithelial differentiation and dynamics, and early development. The aim is to analyze the molecular mechanisms of how tension at tight junctions is transmitted between adhesion proteins and the cytoskeleton, and the roles such processes play during epithelial cell dynamics and differentiation in vitro and during zebrafish gastrulation. (J Cell Biol 208, 821-838, 2015; J Cell Biol 204, 111-127, 2014; Nat Cell Biol 13, 150-166, 2011; Development 136, 383-392, 2009; Development 139, 3897-3904, 2012; Nat Rev Mol Cell Biol 2016).

The positions are funded by the BBSRC and require a PhD in Cell/Molecular/ Developmental Biology, Biophysics, or another related discipline. The persons appointed will have experience in developmental biology, biophysical approaches, molecular cell biology and/or advanced microscopy. Good communication skills and interest in collaborative research are essential.

Informal enquiries about the posts may be made to Karl Matter (email: or Masazumi Tada (
Applications can be be submitted at:
Ref No: 1559085 and 1557441
Closing date: July 15, 2016

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