the community site for and by developmental biologists

A Crumby affair: Cell ingression during gastrulation

Posted by on January 31st, 2017

Comment on “Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation” Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV. Nat Cell Biol. 2016 Dec;18(12):1281-1291   “It is not birth, marriage, or death, but gastrulation, which is truly the most important time in your life.” Lewis Wolpert (1986)   Aptly stated by Wolpert, gastrulation is the fundamental process[…]

In Development this week (Vol. 144, Issue 3)

Posted by on January 31st, 2017

Here are the highlights from the current issue of Development:   Evolving an atypical developmental programme with IMM The brown alga Ectocarpus has alternating haploid (gametophyte) and diploid (sporophyte) generations. Morphologically, these are distinguished by a more complex system of basal filaments in the sporophyte, initiated via symmetric divisions before the apical-basal axis is defined[…]

Lifemap: a zoomable interface for exploring the entire Tree of Life

Posted by on January 30th, 2017

“Nothing in biology makes sense except in the light of evolution” (Dobzansky, 1973). Our knowledge of the evolutionary relationships between all known organisms, the so-called Tree of Life (ToL), is crucial in all fields of biology. Many researchers in evolutionary biology are working on improving the quality and the comprehensiveness of this ToL. This implies[…]

Research Associate/Assistant post at University College London

Posted by on January 30th, 2017

Applications are invited for a Research Assistant/Associate within the Division of Infection & Immunity at University College London in Dr Gillian Tomlinson’s laboratory. We are seeking a highly motivated individual interested in integrating cutting-edge human and zebrafish models to study the immunopathogenesis of tuberculosis. The post is funded by a Medical Research Council Clinician Scientist[…]

BSDB Gurdon Summer Studentship Report (11)

Posted by on January 27th, 2017

Established  by the British Society for Developmental Biology (BSDB) in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the[…]

Let’s move to 4D-biology: building the embryonic inner ear!

Posted by on January 26th, 2017

Comment on Distribution of neurosensory progenitor pools during inner ear morphogenesis unveiled by cell lineage reconstruction, eLife 2017; 6:e22268 Sylvia Dyballa and Cristina Pujades Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain   Reconstructing the lineage relationships and dynamic event histories of individual cells within their native context is central to understanding how the[…]

BSDB Gurdon Summer Studentship Report (10)

Posted by on January 26th, 2017

Established  by the British Society for Developmental Biology (BSDB) in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the[…]

Postdoc position – near Washington DC

Posted by on January 25th, 2017

A position (#121670) is available immediately for a Postdoc Associate to contribute to our studies in neural crest and placodes. The Postdoc Associate will conduct independent research and assist in the training of students in the laboratory of Dr. Lisa Taneyhill at the University of Maryland. Laboratory skills should include the ability to perform various[…]

The people behind the papers: Ehsan Pourkarimi & Iestyn Whitehouse

Posted by on January 25th, 2017

How does a developing embryo coordinate DNA replication with gene transcription? This fundamental question is the focus of today’s paper, recently published in eLife. We caught up with lead author Ehsan Pourkarimi and his supervisor Iestyn Whitehouse, Assistant Professor in the Sloan Kettering Institute’s Molecular Biology programme, to hear the story behind the work.     Iestyn, can you[…]

BSDB Gurdon Summer Studentship Report (9)

Posted by on January 25th, 2017

Established  by the British Society for Developmental Biology (BSDB) in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the[…]