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Catch Me if You Can: An elusive underpinning for Arx(GCG)10+7-mediated apoptosis in X-linked infantile spasms syndrome

Posted by , on 3 June 2020

This post highlights the approach and finding of a new research article published by Disease Models and Mechanisms (DMM). This feature is written by Olivia Howell as apart of a ...
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Stripe by stripe, zebrafish model provides transparent look into Fibrolamellar Carcinoma mechanism

Posted by , on 3 June 2020

This post highlights the approach and finding of a new research article published by Disease Models and Mechanisms (DMM). This feature is written by Joseph I. Kaluzny as apart of ...
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May in preprints

Posted by , on 1 June 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.    A real monster of a month, May, with masses of preprints uploaded by scientists in various stages of ...
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Research Highlight #4: Macrophages in human development

Posted by , on 1 June 2020

Today we return our interest to human development, focusing on a special blood cell: the macrophage. Produced in multiple, stem cell-independent waves, macrophages colonize the developing foetus early on, forming ...
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Research Highlight #3: IL-1 regulates haematopoietic stem cell pool size via PU.1

Posted by , on 25 May 2020

Today, we move to mouse adult haematopoiesis, with an elegant work on inflammation and stem cell biology. As always, feedback is more than welcome! Chronic inflammation is one of the ...
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Research Highlight #2: Blood stem cells heterogeneity arises from accessible chromatin

Posted by , on 18 May 2020

Hi there! Today’s highlight is focusing on a major question for the haematology community: what is causing blood stem cell heterogeneity? Please do not hesitate to let me know your ...
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Shaping the embryo towards gastrulation

Posted by , on 13 May 2020

Kyprianou, C., Christodoulou, N., Hamilton, R.S. et al. Basement membrane remodelling regulates mouse embryogenesis. Nature (2020). doi.org/10.1038/s41586-020-2264-2 Morphogenesis is a complicated network of processes that involve cell shape changes, cell movements ...
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Research Highlight #1: Inhibition of cell cycle regulators alters the EHT

Posted by , on 12 May 2020

Hello everyone! My name is Alessandro, I am a postdoc in love with science, stem cells and blood! I am also a big fan of the Node, The Company of ...
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Birds take flight with help from Sonic hedgehog

Posted by , on 6 May 2020

A Press Release from Development Flight feathers are amazing evolutionary innovations that allowed birds to conquer the sky. A study led by Matthew Towers (University of Sheffield, UK) and Marian ...
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April in preprints

Posted by , on 4 May 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.  With COVID-19 having shuttered labs around the world, it might be a surprise that April saw the highest ever ...
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