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Displaying posts with the tag: actin [Clear Filter]

Staying in shape

Posted by on October 5th, 2018

If you’re into developmental biology, chances are you’ve spent some time in your life thinking about how cells change the shapes of tissues. What would cells need to do in order to prevent change of tissue shape, though? In the text below, I summarize my thoughts on why the question of not changing shape during[…]

Camelid antibodies go fishing

Posted by on May 18th, 2015

Figure 1. “Cytoplasm”, illustration by David S. Goodsell, the Scripps Research Institute.   When contemplating the illustrations by David S. Goodsell (Figure 1), the first thing that stands out is how cells are packed full with those wonderful little machines we call proteins. They move, interact and change shape to produce cellular functions, so our ability[…]

Schwann cells and N-WASp: it always comes down to actin

Posted by on April 22nd, 2011

Axons have such important jobs to do that they require their own support staff.  Schwann cells are responsible for ensheathing axons of the peripheral nervous system with myelin, which allows rapid conduction of action potentials.  The process by which Schwann cells do this was understood to involve cytoskeletal regulators, and a recent paper in Development[…]

In Development, Vol 137 (Issue 14)

Posted by on June 23rd, 2010

Here are the research highlights from the current issue of Development. You can find these on the Development site but we thought it would be useful to have them posted on the Node, too. Brainy signals for actin dynamics During brain development, neurite outgrowth and neuronal migration establish the brain architecture needed for brain function.[…]