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Displaying posts with the tag: biomechanics [Clear Filter]

Gaining traction: What Hippos can teach us about vertebrate embryonic morphogenesis

Posted by on January 19th, 2018

In our recently published paper, we discovered that the Hippo pathway transcription factors have an unexpected role in creating the conditions for the zebrafish body to extend posteriorly during embryogenesis, as well to form the precursors of the dorsal and ventral fins. Here is the backstory of the twists and turns that lead to these[…]

The forces that shape us: Mechanics of mammalian neural tube morphogenesis

Posted by on July 7th, 2017

Introduction to the biomechanics of neurulation Those of us who go to the gym are accustomed to thinking of mechanical forces shaping our bodies. Physiological (e.g. determination of bone mass and architecture), pathological (e.g. aneurysm rupture) and even socio-cultural (e.g. lip plates of the Mursi tribe) examples come to mind. The form of most of[…]

The Third USNCB Symposium on Frontiers in Biomechanics: Mechanics of Development

Posted by on March 8th, 2011

The Third USNCB Symposium on Frontiers in Biomechanics: Mechanics of Development June 21, 2011, Nemacolin Woodlands Resort, Farmington, PA In the fields of tissue engineering, synthetic biology, and regenerative medicine, much can be learned by studying how nature creates tissues and organs in the embryo. Accordingly, the last decade has seen rapidly expanding interest among[…]