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François Guillemot joins the Development team

Posted by on January 10th, 2013

Here at Development, we’re delighted to welcome François Guillemot to the team of academic editors. François will be replacing Alexandra Joyner, who is soon to step down as our neurodevelopment expert. François heads up the Division of Molecular Neurobiology at the National Institute for Medical Research in London, and his research focuses on the regulation of neurogenesis in the mouse forebrain.

I’d like to take this opportunity to thank Alex for her dedication to and enthusiasm for the journal over the last five years, and to welcome François on board. Given that they used to work together, it should be a seamless transition!
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Editorial opportunities at the Company of Biologists

Posted by on November 6th, 2012

Here at Development, and at our sister journal Disease Models and Mechanisms, we are currently advertising two editorial positions.

Within the Development team, we are seeking to recruit a new Associate Reviews Editor with special responsibility for the stem cell field - reflecting the journal’s increasing visibility in that area. Further details on this exciting opportunity are available on the jobs page.

DMM also have a position for a Scientific Editor, and you can find more information on this opening here. Applicants with previous editorial experience are particularly encouraged.

Both jobs will be based at the Company of Biologists’ office in Cambridge, UK, and both provide a fantastic opportunity to work with a small not-for-profit publisher at the heart of the scientific community.
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Scientific Editor Disease Models and Mechanisms

Posted by on November 6th, 2012

Scientific Editor Disease Models & Mechanisms
Based in Cambridge, UK

Joining a young journal in an expanding and important area of research, this is an exciting opportunity for a promising scientific editor to make a significant contribution to a growing open access journal serving a major new biomedical community.

The journal is entering the next phase of its development with the appointment of a team of academic editors, having been managed previously by a professional editor. As part of this evolution of the journal model, we will require the new scientific editor to be flexible in their areas of responsibility. Disease Models & Mechanisms publishes both primary research articles and commissioned front section material and we expect the scientific editor to take a role in both of these areas.

Since the journal serves both basic biomedical researchers and clinicians, applicants will have a PhD or MD with some relevant research experience, and a broad knowledge of model organisms and disease issues, and will ideally already hold an editorial role (we also provide on-the-job training).

Core responsibilities are expected to include:
• Support for the academic editors in their assessment and handling of primary research articles
• Commissioning, handling peer review and developmental editing of material for the front section of the journal
• Writing pieces for the journal, conducting interviews and preparing press releases
• Representing the journal at international conferences and within the wider scientific community
• Creative involvement in the journal’s development and marketing

The Scientific Editor will work alongside an experienced in-house team, and additional responsibilities may be provided for the right candidate.

Essential requirements for the job are enthusiasm, commitment, judgement, integrity and a mature attitude. Candidates should have excellent interpersonal skills, excellent oral and written communication skills, and a broad interest in research and the research community.

The position represents a unique opportunity to gain experience on an exciting new biomedical research journal and offers an attractive salary and benefits.

The Company of Biologists (www.biologists.com) is a not-for-profit organisation, publishing five journals in the biological sciences: Disease Models & Mechanisms, Development, Journal of Cell Science, The Journal of Experimental Biology and Biology Open. The organisation has an active programme of charitable giving for the further advancement of biological research, including travelling fellowships for junior scientists, contributions to academic societies and conferences, and a series of scientific workshops.

Applicants should send a CV along with a covering letter that states their salary expectations and summarises their relevant experience and why they are enthusiastic about this opportunity.
Applicants must be able to provide confirmation of entitlement to work in the UK.

Applications should be sent by email no later than 18th November 2012 to miriam@thecob.co.uk
Informal queries to Miriam Ganczkowski on +44 (0)1223 426 164.
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New Reviews Editor at Development

Posted by on November 6th, 2012

Associate Reviews Editor (Stem Cells) Development
Based in Cambridge, UK

Applications are sought for a new role of Associate Reviews Editor for the stem cell field at Development.

Joining an experienced, expanding and successful team, this is an exciting opportunity for a promising scientific editor to make a significant contribution to one of the major journals in the field of developmental biology. Development publishes primary research articles, reviews and other front section content. The journal is expanding its focus in the stem cell field, and is seeking to appoint a specialist editor to cover this growing area.

Applicants will hold a PhD, ideally in stem cell biology, although outstanding candidates with experience in other areas of developmental biology and with a strong interest in the stem cell field will be considered. Post-doctoral and/or previous editorial experience are highly desirable, although we will provide on-the-job training. The successful candidate will have a broad interest in science, the scientific community and publishing. Excellent interpersonal and literary skills, enthusiasm and commitment are also essential requirements for the position.

Core responsibilities:
• Commissioning, handling peer review and developmental editing of material for the front section of the journal
• Writing press releases, article highlights and material for Development’s community website ‘the Node’
• Representation of the journal at international conferences and within the wider scientific community
• Creative involvement in the journal’s development

The new Associate Reviews Editor will work alongside an experienced in-house team, including the Executive Editor and current Reviews Editor, as well as with our international team of academic editors. Additional responsibilities may be provided for the right candidate.

The position represents a unique opportunity to gain experience on a highly successful life-science journal and offers an attractive salary and benefits. The position will be based in our office in Cambridge, and the contract will be for a three-year period.

The Company of Biologists (www.biologists.com) is a not-for-profit organisation, publishing five journals in the biological sciences: the three established journals Development, Journal of Cell Science and The Journal of Experimental Biology, as well as two newer Open Access journals, Disease Models & Mechanisms and Biology Open. The organisation has an active programme of charitable giving for the further advancement of biological research, including travelling fellowships for junior scientists and contributions to academic societies and conferences.

Applicants should send a CV along with a covering letter that summarises their relevant experience and why they are enthusiastic about this opportunity, and states their salary expectations.

Applications should be sent by email no later than November 26th to miriam@thecob.co.uk
Informal queries to Miriam Ganczkowski on +44 (0)1223 426 164

Applicants must be eligible to work in the UK.
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New Development editor

Posted by on February 1st, 2012

As of today, a new face has joined the team of Development editors, and a familiar one is soon to be leaving us. After 6 very successful years at the journal, Ken Zaret has decided to step down: we will miss him, but we’re sure the extra time he’ll have will be put to great use – both for his research and his other activities. Replacing Ken, and complementing particularly his expertise in epigenetics, we are delighted to have recruited Professor Haruhiko Koseki to the Development editorial team. Haruhiko is Group Director at the RIKEN Center for Allergy and Immunology in Yokohama, Japan. His lab is interested in understanding the molecular basis of epigenetic inheritance, and its consequences on haematopoiesis, stem cell identity and various other aspects of development. We’re excited to have Haruhiko on board, and we wish him luck for his first days and weeks in his new job!
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Development: New Executive Editor

Posted by on November 30th, 2011

I’m the new Executive Editor at Development, taking over after Jane Alfred’s eight years at the journal, and I’d like to take this opportunity to introduce myself. I’m starting here fresh off the plane from Heidelberg, Germany, where I have been working as a scientific editor at The EMBO Journal for the last three years, handling manuscripts in the fields of developmental and cell biology. Before then, my research life is probably best described as “trying to understand how to make an eye”: firstly during my PhD with Matthew Freeman at the Laboratory of Molecular Biology in Cambridge working with Drosophila (where I published my first ever paper in Development!), and subsequently studying morphogenesis of the fish retina in Jochen Wittbrodt’s lab at EMBL Heidelberg.

While I’m no longer in the lab, I’m still fascinated by the subject, and am excited to be getting back to my developmental biologist roots here at the journal. To me, Development is all about publishing by and for the community, and The Node is a big part of that: I’ve been reading it since its inception last year, and I look forward to playing a more active role from now on – I’m sure you’ll be hearing more from me in the future. I also hope to be meeting many of you in person over the coming months and years. For now, though, all that remains is for me to thank Jane for the fantastic job she’s done here: I have big boots to fill, but I hope I’m up to the challenge!
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An Interview With Ottoline Leyser

Posted by on October 25th, 2011

(This interview originally appeared in Development.)

The Sainsbury Laboratory at the University of Cambridge is a new research institute that aims to achieve an integrated understanding of plant development. Its Associate Director is the new plant Editor of Development, Ottoline Leyser, who is also Professor of Plant Development at the University of Cambridge. We recently caught up with Professor Leyser and asked her about the Sainsbury Laboratory and about her own research interests.

When did you first become interested in plant development?


To me, plant development has always been much more interesting than animal development, because of its plasticity. In plants, the body plan is incredibly flexible: one genotype can occupy an extraordinary range of phenotype space. I’ve always thought that was just amazing.


I did my undergraduate degree here in Cambridge, in the Genetics Department, not in plant science. We had this absolutely fantastic interdepartmental development course that was taught by John Gurdon, Peter Lawrence and many other wonderful people. It was very striking, the contrast between what was happening in animal development, which was being transformed by Drosophila genetics, by Christiane Nüsslein-Volhard, Eric Wieschaus and others, and what was happening in plants: despite the long tradition of genetics in plants, developmental genetics somehow hadn’t really taken off. But in the final year of my undergraduate degree, there were the first hints of Arabidopsis as a model organism, driven at least in part by Elliot Meyerowitz, who is now the inaugural director here at the Sainsbury Laboratory. So, there was suddenly a very exciting opportunity to push things ahead in plant development using developmental genetics. I started looking for a PhD position in an Arabidopsis lab and, fortunately for me, Ian Furner had just arrived back from the USA clutching some Arabidopsis seed in a tube, so I stayed in Cambridge and did my PhD with him, studying meristem mutants in Arabidopsis.


What are you working on at the moment?


I’m working on the role of plant hormones in integration of the endogenous and environmental signals that control the plant body plan. We’re looking principally at shoot branching control and are trying to understand how every individual axillary bud on the plant makes a decision about whether to activate or not, depending on multiple inputs. It’s really a question of signal integration.


You’ve recently moved your lab from York to Cambridge to set up the new Sainsbury Laboratory. How did the lab move go?


It’s still an ongoing process. We’re pioneers down here, who have had to deal with a very fabulous but nonetheless brand new and, at the time, unfinished building. But now that the first results from experiments carried out in the new lab are coming in it’s very exciting. Meanwhile, there’s still a core of people in York, partly because some people didn’t want to move and partly because we’re in the middle of a rather long-term ten-generation Arabidopsis experiment, which I didn’t want to move.



Read the rest of this entry »

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A career as editor

Posted by on May 19th, 2011

I was a PhD student with Peter Walter, studying protein translocation across the endoplasmic reticulum. I did very well as a student, publishing six research papers during that time. After that, I was a postdoc with Christiane Nüsslein-Volhard and then with Yuh-Nung Jan, studying oogenesis and pattern formation in Drosophila. Throughout my training, people handed me their papers to read and asked me to attend their practice qualifying exams because I was always looking for the big picture, always needing to know why they were doing the experiments in the first place. Time and again, friends suggested I become an editor. I mostly laughed at them, in part because I wasn’t really sure what an editor did, and in part because there seemed to be so few jobs for editors that I never thought I’d get one. Anyway, I was good at the bench and I couldn’t imagine disappointing my father by not taking a job in academia.

In 1993-4, I went on the job market, looking at standard faculty positions. I received some offers, including one from Vanderbilt University, where I am now. But I was resisting accepting a position, and some friends – who were also on the job market at the time – sent me to a career counselor. The counselor’s husband was a bench scientist, so she had some sense of my career until that point, and asked me a very simple question, one that I had never asked myself: “If you didn’t have to worry about how much money you made, or what anyone else thought of you, what would you do?” What surprised me was that I knew the answer to that question: I’d be a student for the rest of my life.

When I said that, I realized that what I loved about being in science was knowing something today that no one knew yesterday, and that it didn’t matter so much if I learned it by my own hands, or over coffee with a friend. This calmed me down a lot about the idea of starting up a lab, as I had been worrying about going around claiming other people’s work as my own.

When I got back to the lab that afternoon, I went into our lunch room and opened an issue of Cell. Near the front cover, there was an ad for an editor, and they were looking for someone with expertise either in cell biology (my graduate training) or developmental biology (my postdoctoral training) – and I thought to myself that it seemed an awful lot like being a student, so I applied for the position. The short version of this story is that I got the job, and I was a full time professional editor for about a dozen years, including a few very exciting years as the Executive Director of Public Library of Science, before returning to academia to my current position at Vanderbilt University. I still spend most of my time as an editor, most notably as the Editor-in-Chief of Development’s newest sister, Disease Models & Mechanisms.

Being an editor is really very much like being a student. You encounter lots of interesting and new science every day in a broad range of fields. But, at least for those of us who decide which research papers to publish in high profile journals such as Cell, it is also about being able to judge science. As an editor, you will have to turn away most of the papers you receive, and explain your reasoning. I think that editorial decisions need to be timely, constructive, transparent, and fair – or at least as much as they can be, given the need to turn complicated issues and shades of gray into stochastic decisions, and the need to keep confidential information confidential.

Editors and journals can be important partners to science. Through editorial policy they can help scientists do the right thing, such as sharing information and reagents; and through publishing policies, such as leaving copyright with the author or providing free access to published work, they can contribute to accelerating science itself. Editors are both gatekeepers and guardians of our treasury of scientific information, and editors need to behave responsibly and ethically. Thankfully, the Committee on Publication Ethics, of which Company of Biologists is a member, helps editors know and do the right thing.

For any trainees interested in being an editor at a journal like Cell, I encourage that you participate in journal clubs. A lot of the work of an editor is to assume the best of all possible worlds – that the conclusions are justified by the data and the interpretations are reasonable – and then assess how important the conclusions are to and beyond the field. Journal clubs are great ways to practice this – but be careful not to miss the forest for the trees, and to get too focused on the weakest part of the paper, which may be tangential to the overall conclusions. Also, take the time to go to seminars and meetings and talk to scientists in other fields and at other institutions. A scientist too buried in his own experiments to pay attention to the exciting discoveries around him is unlikely to enjoy or succeed at an editorial career.

Oh, and when I told my father, he was delighted. You see, he’d wanted me to be a writer, and considered this an enlightened combination of my twinned loves of science and language. And he was right.
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A career in publishing: a developing story

Posted by on January 25th, 2011

In a follow up to Eva’s first post in our alternative careers series about how a research background in developmental biology can lead to a career path that lies outside of research, I hope that my description here of how I made the move from a PhD in developmental genetics to a career in publishing will be of use to anyone else out there in the community who is considering making a similar move.

My journey in science began with an undergraduate degree, not in genetics, but in pharmacology at King’s College, London, where the most important thing I learned was that I was much more interested in genetics and development than I was in pharmacology, interests that led me to a PhD with Ian Jackson and Cathy Abbott at the MRC Human Genetics Unit in Edinburgh. From there, I became a post doc in Val Wilson’s lab.

At the time of my PhD, Ian was a regular contributor to the journal club section of Trends in Genetics, and when short on time, he would ask me to write these brief pieces on a paper of interest in his place. I came to enjoy this writing exercise and, as a result of it, was offered other writing opportunities, such as summarizing new mouse knockout phenotypes for a knock out database then under development at BioMedCentral. (In fact, one of the journals I had to check every month for new knock out papers was Development.)

As my fondness for writing grew, another opportunity arose towards the end of my PhD that helped me to choose between the different career paths I was starting to consider: research, science journalism, or a job in science publishing. This opportunity took the form of a Media Fellowship from the British Science Association. These fellowships place British scientists with a media organisation for a couple of months, where they learn to work within the constraints of the media to produce interesting stories about science. I was placed with the Guardian, a national daily newspaper in the UK, where I spent several weeks under the tutelage of Tim Radford,  who was its science editor at the time. Under the guidance of Tim’s red pen, I wrote science-related stories covering a wide range of topics, from archaeological discoveries (see picture), to cancer, and even about why Mozart had such a foul tongue (he had Tourette’s, so the story went). I also had many a story ‘spiked’ by the news desk editor, when it failed to pass the “so what?’ barrier that most science-related stories have to pass. This experience taught me several important things: how to write concisely and engagingly about science; about the constraints that journalists work under; and about the importance of scientists learning to communicate clearly and succinctly with the media about their work. But it also left me a little disheartened about the difficulties of getting good science stories covered, even by a reputable newspaper such as the Guardian, when they have to compete for space with stories about politics, crime and celebrity gossip, all of which have a more tangible ‘human interest’ angle for most news desk editors.



As a BSA media fellow, you write about whatever story is sent your way

As a result, I returned to the lab knowing that a career in science journalism was probably not for me while suspecting that my scientific interests were too broad to remain in research. But first I needed to give research a proper chance because to leave it felt like an irreversible decision not to be taken lightly. I have never regretted my time as a post doc; I learned much about embryology from Val, which has stood me in good stead to this day. My postdoc also broadened my scientific horizons and contacts, while giving me time to learn more about career options in publishing.

In time, I successfully applied for the job of assistant editor at Trends in Molecular Medicine (TMM), having heard good things about the Trends journals while writing for them as a student. I joined the office in Cambridge, which became a training ground for a generation of British editors, many of whom still work in publishing today. From feedback on my application, it became clear that I was offered this post because my CV showed that I was demonstrably interested in writing and in science communication; skills that complemented my role on TMM, where I assisted with developmentally editing reviews and was responsible for copyediting the content of the journal, while occasionally writing news stories for its front section and being dispatched to do live conference reporting for BioMedNet. It was a great first job in publishing, but not, as I subsequently discovered, what I really wanted to be, which was a commissioning editor. And so within a year of being recruited to TMM, I successfully applied for the role of Editor of Trends in Genetics, where I began to learn properly, for the first time, the job of a commissioning editor.

I have at heart been a commissioning editor ever since. In science publishing, a commissioning editor’s job is to determine the content of a journal, book or journal section and then to invite people - such as scientists, science writers and commentators, to write for their publication. The commissioning part of the job requires an editor to travel widely to conferences and to keep in close contact with their field, so that they can identify the topics that are the hottest and most interesting to commission articles on. The editorial part of the job comes in developmentally editing articles to improve their focus, structure, scientific content and accessibility and in making editorial decisions about whether a manuscript should be revised, accepted or rejected in response to the reviewers’ and your own editorial assessment of it.

My own experience as a commissioning reviews editor was further strengthened when I moved from Trends in Genetics to Nature Reviews Genetics,where I joined Mark Patterson and Tanita Casci to launch NRG as one of the first Nature Reviews journals. Launching NRG was a hugely exciting project that taught me not only a fantastic amount about genetics from working with Mark and Tanita and our many great authors, but also how to launch a journal from scratch. When Mark stood down as Editor in Chief of NRG, I successfully applied for this role and from this position moved to Development: my first experience at managing a primary research (and not-for-profit) journal.



My signed copy of the launch issue of NRG


As Executive Editor of Development, I wear many hats: I manage the in house journal team, and commission and handle reviews and other front section articles, together with Seema Grewal, the journal’s associate reviews editor. I also work closely with Development’s Editor in Chief, first Jim Smith and now Olivier Pourquie, and our team of dedicated scientific editors in handling papers and author queries, and in developing the journal editorially. I am also responsible for the journal’s online presence. And in response to a Development readers’ survey in 2009, I kick started another new and exciting launch project that, once we had Eva on board, came to fruition as this: the Node, which I had the honour of naming.

Being a managing and commissioning editor is a highly interesting and rewarding role. As an editor, you learn about new scientific findings every day and have to assimilate a lot of new information quickly, and you work within a wider community, building sometimes long-standing relationships with researchers, authors and reviewers. I’m particularly fortunate in having the developmental community to work with, a community I’ve found to be tremendously collegial. And, occasionally, I’m asked to do other fun things, such as speaking at meetings about publishing and interviewing speakers at the CSHL symposia.

Getting that first foothold in publishing is by far the hardest, most competitive step of all. I was successful in making this initial move by being able to demonstrate my enthusiasm for writing about and communicating science, and by having gained experience while still in research that significantly strengthened my application for my first editorial job. Other Editors, particularly primary manuscript editors who mainly handle research papers, may  have taken different paths from research to publishing, and it’s our hope that they will also share those different career paths and their experience with you here on the Node.
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An interview with Patrick Tam

Posted by on November 25th, 2010

(This interview by Kathryn Senior originally appeared in Development on November 23, 2010)

Patrick Tam’s research is focused on the cellular and molecular mechanisms of body patterning during mouse development. He agreed to be interviewed by Development to talk about his interest in mouse development, new concepts in gastrulation, X-linked diseases and his dream of an African safari.

Did you always intend to have a career in developmental biology?

I was lured into science at high school as I listened to my biology teacher reminiscing about his romance with plant biochemistry during his university days. It was really no surprise that I chose biology over medicine as my degree and then headed onto postgraduate research without a second thought. It might sound incredible but there was not a proper course on developmental biology (or embryology, as it was known) in the entire Bachelor of Science curriculum of my university in those days. To fill this gap in my education, I made a definite decision to study rodent embryo development – first in Hong Kong, and later in London with Michael Snow. This was a time when research in mouse development was taking off in a big way in the UK and so the rest, as they say, is history.

What has influenced your decisions about institutions and locations?


Before I finished my PhD, I had already accepted a faculty position in the newly founded Medical School at the Chinese University in Hong Kong. Luckily, I did manage to squeeze in one year of postdoctoral training at the University of Texas at Austin. This proved to be critical for broadening my research experience and I learned a great deal more before taking on the job back home.

Joining a young institute happened to be a good decision: there were ample start-up resources and also the flexibility that I needed to be able to run the laboratory the way I wanted it. The academic appointment offered relatively stable support for my research during this formative phase of my career. The downside was coping with the demand of teaching commitments, and being the only laboratory working on mouse development made it quite hard to maintain research momentum. My next move to a research institute in Australia was a very positive one as it allowed me to develop further in a research-intensive and intellectually stimulating environment. Having access to first-rate facilities and interacting and networking with a larger community of developmental biologists enabled me to focus and move forwards much faster.

You have been a great pioneer in applying micromanipulation and embryo culture research for investigating early mouse development: how did you get into this originally?

My PhD project was to characterise the developmental fate of an active multiplying population of cells in the epiblast of the gastrulating mouse embryo. I had little idea how challenging this would turn out to be! Initially, we focused our efforts on developing a reliable whole-embryo culture method by tweaking the protocol established by Dennis New for culturing rat embryos. We then tried to apply the conventional `slash and burn’ and `cut and paste’ techniques to study cell fate and tissue differentiation. I owe Rosa Beddington an enormous debt of gratitude for introducing me to the art of embryo manipulation during my sabbatical at Oxford University in the mid 80s: my collaboration with her has had a lasting impact on my career. Ultimately, my postgraduate project evolved into a consuming exercise of fate-mapping all three germ layers and their immediate derivatives. The work took three decades but realizing that I had completed my original objective to the best of my ability was a very satisfying moment in my scientific career. Read the rest of this entry »
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