the community site for and by developmental biologists

Displaying posts with the tag: hair-follicle [Clear Filter]

Layered patterning systems in hair development

Posted by on September 28th, 2017

The story behind our recent paper  ‘Hierarchical patterning modes orchestrate hair follicle morphogenesis‘ , finding that distinct patterning mechanisms can co-exist during embryonic organ formation.   From the spots of a leopard and stripes on a zebra to the pigmentation of sea shells and arrangement of sand dunes in a desert, repeating patterns are present[…]

Gone today, hair tomorrow? Changes in dermal papilla cell number drive hair thinning and loss.

Posted by on May 28th, 2013

  Over the course of a lifetime, each hair follicle makes a series of new hairs, temporarily ceasing hair production before beginning again anew.  This has focused attention on the epithelial stem cells that periodically renew the follicle and regenerate the progenitor cells that form the hair shaft.  Between the cachet of stem cells and[…]

In Development This Week (Vol. 138, Issue 22)

Posted by on October 25th, 2011

Here are the highlights from the current issue of Development: The skin-healing touch of Lhx2 Skin repair after injury involves the recruitment of undifferentiated progenitor cells from nearby hair follicles (HFs) into the regenerating epidermis. The bulge and the secondary hair germ of HFs contain distinct populations of epithelial stem cells, and now Vladimir Botchkarev[…]

In Development this week (Vol. 137, Issue 23)

Posted by on November 9th, 2010

The current issue of Development is now online! Here are the research highlights: Klf5: a multifaceted regulator of cell fate Kruppel-like transcription factors (Klfs) induce and maintain pluripotency in embryonic stem cells (ESCs), and Klf4 is one of the factors used to create reprogrammed iPS cells. The role of Klfs in the specification of the[…]