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PhD position: Chromosome Dynamics During Spermatogenesis in Drosophila, University of Zurich, Switzerland

Posted by on April 19th, 2018

We seek candidates interested in completing a PhD thesis within the framework of a research project (46 months) funded by the Swiss National Science Foundation (SNF). Chromosome reorganization during spermatogenesis is dramatic. Beyond meiosis, it includes chromosome compaction into an elongated sperm nucleus which is accompanied by an almost complete exchange of histones with sperm[…]

Spindle asymmetry drives non-Mendelian chromosome segregation

Posted by on December 20th, 2017

I studied molecular mechanisms of faithful chromosome segregation in mitosis and meiosis during my PhD and wanted to continue studying chromosome segregation but from a different angle. While looking for a postdoc lab, I learned about a phenomenon called meiotic drive where the selfish genetic element preferentially segregates into the egg during female meiosis in[…]

The people behind the papers – Simon Lane & Keith Jones

Posted by on October 4th, 2017

Checkpoints ensure that mouse oocytes with DNA damage arrest in meiosis I, preventing non-viable embryo formation, however the mechanisms which activate this checkpoint have so far eluded researchers. This week we feature a paper published in the latest issue of Development that reveals that the unique ability of mouse oocytes to sense DNA damage by[…]

An interview with Melina Schuh

Posted by on January 14th, 2016

This interview first featured in the Journal of Cell Science and is part of their interview series Cell Scientists to Watch.   Melina Schuh received her diploma degree in biochemistry from the University of Bayreuth, Germany, where she completed her Diploma thesis with Stefan Heidmann and Christian Lehner. She went on to do her PhD with[…]

From our sister journals- October 2015

Posted by on October 21st, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.             Modelling Alzheimer’s Disease in vitro Hall and colleagues established an in vitro model of Alzheimer’s Disease by culturing and differentiating embryonic stem cells isolated from the APPsw transgenic minipig. They use this system to[…]

From our sister journals- July 2015

Posted by on July 28th, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.         Drosophila helps to elucidate the effects of radiation therapy Children who are exposed to cranial radiation therapy (CRT) to treat brain tumours are at increased risk later in life for neurocognitive, motor and seizure disorders.[…]