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Basic Scientist – Assistant, Associate, or Professor

Posted by on January 18th, 2012

 

 

OHNS Logo 2010 Red Master 1

 

 

BASIC SCIENTIST


ASSISTANT, ASSOCIATE, or PROFESSOR


DEPARTMENT OF OTOLARYNGOLOGY / HEAD AND NECK SURGERY


STANFORD UNIVERSITY SCHOOL OF MEDICINE


 


 

Faculty Position in the University Tenure Line- Basic Sciences

Stanford SOM

 

 

The Department of OHNS (http://med.stanford.edu/ohns/) is recruiting for a basic science tenure-track faculty position.  The successful candidate will be appointed at the level of assistant, associate, or full professor.

 

Scientists from a wide variety of disciplines are welcome to apply as long as their research relates to issues relevant to otolaryngology.  A few illustrative fields include developmental biology, genetics, molecular and cellular biology, biophysics, cancer, auditory physiology, voice physiology, auditory and vestibular prosthesis development, bioengineering, stem cell and gene therapy.  Collaborations with academic clinicians is encouraged.  The successful researcher will be part of an interdisciplinary and collaborative team in a lab close to Stanford campus with ample opportunity for interaction with a broad spectrum of scientists including world-class programs in neuroscience, genetics, biomedical engineering, and bioinformatics, to name a few.

 

Resources available include substantial funds for equipment acquisition and program initiation, as well as appropriate laboratory facilities.

 

The predominant criterion for appointment in the University Tenure Line is a major commitment to research and teaching.

 

Stanford University is an equal opportunity employer and is committed to increasing the diversity of its faculty.  It welcomes nominations of and applications from women and members of minority groups, as well as others who would bring additional dimensions to the university’s research, teaching and clinical missions.

 

Letters of inquiry and curriculum vitae as well as the names and addresses of five references should be sent to:

 

Stefan Heller, PhD – Chair of Basic Science Search Committee

Department of Otolaryngology – Head & Neck Surgery

801 Welch Road, Stanford, CA 94305-5739

sheller@ohns.stanford.edu

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Some of the things we have done during these two weeks

Posted by on October 27th, 2011

We have now finished the first two weeks of the course. Over these two weeks the students have learned about Drosophila as a model organism and how to set-up a Drosophila lab. They have learn about the genetics of Drosophila, which took quite some time, but now I am sure it is almost like their mother tongue. They have also learned basics concepts in neuroscience, such as the nature of neural impulse, and basic concepts on how neurons work to produce adaptive behaviors. During the practicals among other things they have learned  how to do muscle recordings of neuronal activity with inexpensive amplifiers. They have recorded from the legs and wing muscles of grasshoppers (see picture 1)! and observed under the microscope a multitude of different insects, which all together helped them to appreciate in the practice the nature of the neural impulse and the diversity of sensory and motor systems used by insects.



The students also now know how to collect virgins for their fly crosses, and how to dissect brains out of Drosophila larvae, and look at them under the fluorescent microscope.  We have managed to install a webcam on the fluorescent microscope, so that the students can take pictures of the fluorescent preparations that they look under the microscope. The images resulting from this system are actually much better than we expected (see picture 2).



The students have learned about mechanosensory, chemosensory, visual and motor systems during the theoretical lectures, and they have looked at the wild type behaviours of flies and other big insects during the practical sessions (see picture 3).



They have also performed inexpensive cutting-edge neurogenetic experiments on genetically modified larvae. It is being intense but the effort is worthwhile, now they are ready for the lab work of the last week, during which they will need to apply everything they have learned!

 
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My journey to scientific editing

Posted by on May 24th, 2011

Although I’m no longer working at the bench, I still think of myself as a scientist. During grad school and much of my post-doc, I assumed that I would follow the “grad student to post-doc to professor track” so that I could continue to be paid to learn for the rest of my life. I’ve come to find out that many alternatives to the traditional academic path, like my current job as a scientific editor at Cell, enable life-long scientific learning.

For as long as I can remember, I’ve always loved learning about the natural world. When I went to college, I thought I wanted to be a medical doctor, but several summers working in labs and one summer studying animal behaviour changed my mind. I was bitten by the basic science research bug. My PhD thesis work focused on mitochondrial morphology and inheritance, but I also pushed myself beyond my cell biology and genetics comfort zone into areas like biophysics, biochemistry, and computational biology. Six years and three first author papers later, the Damon Runyon Cancer Research Foundation awarded me an opportunity of a lifetime. They funded my post-doc fellowship proposal on dissecting the connections between cell proliferation and differentiation in the zebrafish retina.

My post-doc was challenging – it stretched me emotionally, culturally, and intellectually. The transition from yeast cell biology and genetics to zebrafish developmental biology was more difficult than I had anticipated, but my lab mates, husband, and friends provided the support I needed to succeed. Deciding to leave the lab – my projects, my colleagues, and my friends – was one of the most difficult decisions I’ve ever made. When I talked with my advisor about the possibility of working as a scientific editor, he tried his best to be supportive but also tried to convince me to stay on in his lab. Unlike other post-docs who had moved onto non-academic positions, he (and many of my peers and colleagues) told me that I “have what it takes to be an academic researcher”.

Were they wrong? No. I actually agree with them. Intellectually and emotionally, I am suited to academic research. I delight in thinking and discussing biological questions; I enjoy working collaboratively as well as individually; and I am keen to share my knowledge with others by teaching and mentoring. I am, however, not well suited to the uncertainty that comes with tight funding and shrinking university budgets.

Near the end of the third year of my post-doc, with fellowship money running out, I began to worry that my research, while important and interesting to me, wasn’t likely to make into the high-profile journals (this is something that I never really thought about before; I always just wanted to do the best research in an area that interested me). I applied for several research/teaching assistant professorships back in the US, and I received very nice rejection letters. Around this time, I also began to notice that many scientists whom I respected were struggling to secure funding and spending much of their time carrying out administrative duties. Together, these events motivated me to think about what I was really doing in academic science. Was there something besides being a professor that would satisfy my desire to learn and share my enthusiasm for scientific discovery?

Throughout grad school and my post-doc, I participated in scientific outreach events – hosting high school students in the lab during the summer, working with non-scientists to explain our work to the public (you can listen to the result of one of my favorite collaborations, “Fish Eye/Fix Me”), visiting local schools and science fairs, and even starting my own blog called post-doc perspective. After participating in the 2010 Santa Fe science writers workshop, where I met fantastic people interested in learning about the best ways to communicate scientific knowledge and scientific discoveries, I thought I might use my talents to become a science editor/writer. When the job offer from Cell came, it was a no-brainer.

Some people were happy when I told them I would be starting a job as a scientific editor of Cell, a few of them even tried to become my new best friend. Others were horrified, asking how I could dream of leaving science. I explained that I didn’t see it as leaving science at all, simply as participating in a different aspect of the scientific process.

I began my scientific editing career with the hope that I would be able to facilitate the communication of scientific breakthroughs with integrity, honesty, and fairness. I’ve been an editor for less than a year, and in that time I’ve come to appreciate that scientific editing is a very challenging job; it comes with great responsibility, but it is also a lot of fun, especially for someone like me who loves to learn. At this stage of my career, I can say with confidence that this is the right place for me. I love the intellectual challenges that come with being an editor at Cell, and my husband is thankful that I’m no longer frustrated by experiments not working. I enjoy working with authors and reviewers to ensure that the scientific studies we publish are accurate and at the forefront of their respective fields, and I am thrilled to be part of a team of scientists, writers, and illustrators who work hard to communicate scientific discoveries in the best way possible. If you enjoy reading and writing and learning about biology from reading papers and attending journal clubs, scientific editing might be a good fit for you.

For those who are interested, my undergraduate degrees in biology and chemistry (and summer research experiences) are from at Duke University. I earned my PhD in biochemistry, cell and molecular biology from Johns Hopkins Medical School, and I carried out my post-doctoral research at the University College London.
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SfN meeting: a 21st century event

Posted by on November 3rd, 2010

conference venue: the San Diego Convention CenterThe annual meeting of the Society for Neuroscience kicks off in San Diego at the end of next week, and there are a lot of interesting updates even for people who, like me, are sadly *not* attending.

First of all, if you’re planning to go but haven’t yet registered, you can register on site, but it’s cheaper to register online, even this close to the actual event.

The SfN has also once again selected dedicated “Neurobloggers” to cover the meeting, so you can follow their blogs for updates during the entire conference. For the “development” track of the meeting, the official SfN bloggers are Anahita Hamidi at Genetic Expressions, and Jason Snyder at Functional Neurogenesis. Big congrats to Anahita and Jason. I’ll be following their updates and will be sure to highlight them on our Twitter account once in a while.

Speaking of Twitter, the SfN is also encouraging attendees to use Twitter to talk about the meeting, using the official #sfn10 hashtag, and they have their own account as well. This is truly 21st century conferencing!

In an independent effort, two members of Labspaces have planned a get-together for Twitter-using attendees of the SfN meeting. They’ve called it B.A.N.T.E.R. (“Bloggers and Neuro-Tweeps Engaging Recreationally” - you can always spot biologists by their propensity for far-fetched acronyms…) and it will occur on the evening of November 15, right in the middle of the conference period. More info here.

It seems that, even though I can’t be there, I’ll still be able to follow the entire meeting online, down to the social events! If you are there, don’t forget to drop by the Company of Biologists’ booth to say hello. (A helpful insider tip: our best swag always runs out on day one at big meetings, so visit early!)

And if any Node readers applied to be an SfN blogger but didn’t get selected, remember that you can always write for the Node if you want to reach a large audience of scientists!
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Pleiades Promoter Project

Posted by on September 27th, 2010

ResearchBlogging.orgA recent paper in PNAS describes the development of MiniPromoters: human DNA promoters of less than 4 kb, designed to drive gene expression in specific areas of the brain. The initiative is called the Pleiades Promoter Project, and so far they have confirmed brain-region specific activity in knockin mice for 27 of their MiniPromoters. The final goal is to produce 160 fully characterized MiniPromoters to drive gene expression in defined brain regions.

The project is a spin-off of the Mouse Atlas Project (hence the name “Pleiades”: in Greek mythology, the Pleiades were the daughters of Atlas). To create the MiniPromoters, the researchers have computationally identified regulatory regions associated with brain-region or cell-type enriched gene expressions. Information about region-specific expression came from the Mouse Atlas Project as well as from the Allen Brain Atlas, which maps the human brain.


Several MiniPromoters driving LacZ in different areas of the mouse brain. (Part of Figure 5 from PNAS paper)

The MiniPromoters are designed to work in both mouse and human brains. While the Pleiades website emphasizes the ultimate goal of selective target delivery in gene therapy, the MiniPromoters can also be used to drive reporter expression in cell types of interest, for example to follow development of particular areas of the brain.
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