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Displaying posts with the tag: zebrafish [Clear Filter]

Sex-reversal in adult fish

Posted by on July 27th, 2013

Dranow DB, Tucker RP and Draper BW. Germ cells are required to maintain a stable sexual phenotype in adult zebrafish. Developmental Biology 376: 43-50. Adult sex-reversal  –  the change of primary sex (gonadal sex) and secondary sex characteristics and  to another sex during adulthood, occurs in many fish species and is triggered by social or[…]

Fish, pharma & flamenco: highlights of the 6th Zebrafish Disease Models workshop

Posted by on July 24th, 2013

Set against a beautiful backdrop of baroque architecture and cobbled streets in Murcia, Spain, the 6th Zebrafish Disease Models workshop (ZDM6) kicked off with an awe-inspiring keynote talk on developing therapeutics using zebrafish, given by Leonard Zon. Regaling the audience with the stories behind two approaches that have shown concrete clinical promise since their discovery[…]

“Working with Zebrafish Genome Resources” Workshop during the 8th European Zebrafish Meeting

Posted by on July 18th, 2013

This was my first time in lovely Barcelona. I travelled from London the day before the zebrafish meeting kicked-off (in order to be well rested and alert for all the talks and posters!). I attended the “Working with Zebrafish Genome Resources” workshop and I have to say it was absolutely helpful for any scientist working[…]

My first encounter with the fish community

Posted by on July 15th, 2013

I was really looking forward to attending the European Zebrafish Meeting. The fact that it took place in the amazing Barcelona was, of course, a bonus point, but the main reason why I was looking forward to it was that it was a fish conference. Before I was the Node community manager, I was a Drosophila[…]

The Node at the Zebrafish meeting in Barcelona

Posted by on July 5th, 2013

Next week will see the 8th european zebrafish meeting happening in Barcelona, Spain. The Node will be there, and (if there is internet available) we will be tweeting from the conference using the hashtag #ezfish2013. So follow us on Twitter to find out what is happening! In addition, we have a group of Node zebrafish[…]

From Sequence to Function

Posted by on May 17th, 2013

  It took longer than the human genome, if by only a few years, but it has finally arrived. The sequencing of the zebrafish (Danio rerio) genome reported in Howe et al. is one of two zebrafish publications to recently appear in  the journal Nature.  The second article, Kettleborough et al., makes use of this[…]

Stripes and Stem Cells

Posted by on March 7th, 2013

You didn’t stop developing once you were born (or hatched).  Our infant selves barely resemble ourselves as adults, thankfully, and stem cells play an important role in this continued development.  A recent paper describes the identification of a stem cell niche that generates the melanophores that are responsible for the color patterning in adult zebrafish.[…]

Post-Doctoral Research Associate position at University College London

Posted by on November 23rd, 2012

Post-Doctoral Research Associate position at University College London Cancer Institute The group is based at the Cancer Institute at UCL and works on modelling inherited and acquired haematopoietic diseases using the zebrafish. The goal is to generate relevant models to study the genetics of these disorders and perform chemical screens to identify novel therapeutic targets[…]

Piecing together the squint puzzle

Posted by on July 27th, 2012

Here is the backdrop for our recent paper in Development, “Dorsal activity of maternal squint is mediated by a non-coding function of the RNA”:  This work follows up a previous publication from my laboratory where we showed that knock-down of maternal squint (sqt) or ablation of sqt-containing cells led to loss of dorsal structures in[…]

Loving zebrafish with all my heart

Posted by on June 8th, 2012

I would have thought that all organisms heal a broken heart the same way humans do (bad movies and cheap wine), but I was wrong.  Some organisms, such as zebrafish and newts, are able to regenerate heart tissue where injury, such as myocardial infarction, occurs.  Understanding tissue regeneration is a necessary leap in generating successful[…]