Postdoctoral Research Associate endothelial-to-haematopoietic transition, development of HSC, YAP / TAZ mechanosignalling
Posted by Alexander Medvinsky, on 22 June 2023
Job type: Postdoctoral Research Associate
Location: Centre for Regenerative Medicine, University of Edinburgh
Closing Date: 26 June 2023
A postdoctoral research associate position is available to work on analysis of mechanisms underlying the endothelial-to-haematopoietic transition (EHT) and generation of haematopoietic stem cells. You will use embryonic aorta-gonad-mesonephros (AGM) cultures and ES cells to explore effects of mechanical cues and signalling microenvironment. The study is built on long-standing expertise of Medvinsky’s group in the area of developmental haematopoiesis (https://www.ed.ac.uk/regenerative-medicine/research/alexander-medvinsky). Micropatterned substrates will be employed to enhance precision and manipulation of culture conditions (collaboration with Dr G. Blin’ group “Quantitative Biology of Pattern Formation”, https://www.ed.ac.uk/regenerative-medicine/research/guillaume-blin).
You are encouraged to apply if you have expertise in developmental biology, cell signalling, cell culture and imaging. The position is available until 28/02/2026. For enquires, please email Alexander Medvinsky (a.medvinsky{a}ed.ac.uk) including motivation letter and your CV.
Salary: UE07 £36,333 Per Annum (can be higher depending on experience)
Start date: 1 July 2023
Closing Date: 26 June 2023
Scientific fields: Cell fate control and differentiation, Gene regulation, Stem cells, Haematopoiesis, Signalling, Tissue engineering and organoids
Model systems: Mouse, Human
Duration: Fixed term
Minimum qualifications: PhD