Postdoctoral position in breast stem cell biology and cancer biology

A postdoctoral position is available in the Briegel Lab in the Department of Surgery – Molecular Oncology Program at the University of Miami Miller School of Medicine – Miami, Florida. We study WNT transcriptional/epigenetic mechanisms in normal and malignant breast epithelial stem cell development. Our lab is affiliated with the NCI-designated Sylvester Comprehensive Cancer Center (SCCC) with access to state-of-the art facilities. The SCCC has a vibrant Tumor Biology and Epigenetics Research Program that offer trainee research awards and career development opportunities for Postdocs to foster their transition to an independent career. https://umiamihealth.org/en/sylvester-comprehensive-cancer-center/research/research-areas/research-programs

Applicants with prior experience in any of the following areas are highly encouraged to apply –genomic high-throughput analysis (ChIP-seq, CUT & RUN, HiC-seq), single cell transcriptomics, protein-protein interaction, gene knockout and transgenic expression, stem cells, cancer biology, organoid cultures, mouse model, and/or tumor immunology.

Projects:

– Reprogramming of stem cell/differentiation states and lineage identity during malignant breast development.

– Crosstalk between cancer stem cells and the immune system.

The long-term goal of the Briegel lab is to identify molecular determinants that can be developed into cancer stem cell-targeted interventions to prevent and reduce the mortality from metastatic breast cancer.

Profile required:

– Recent Ph.D. in molecular/cell biology, biochemistry, stem cell biology, cancer biology and/or immunology

– Demonstrated expertise in genome sequencing approaches, protein-protein interaction studies, gene regulation, epigenetics and/or tumor immunology

– Record of publications in peer-reviewed journals

– Excellent oral and written communication skills

– Self-motivated

– Ability to work in an international and interdisciplinary team

Information on how to apply:

Please send your CV with a cover letter stating your scientific background and interest, and the contact details of your advisors to kbriegel@med.miami.edu

or apply here:

https://umiami.wd1.myworkdayjobs.com/UMCareerStaff/job/Miami-FL/Post-Doctoral-Associate_R100070010