Welcome to our monthly trawl for developmental biology (and related) preprints. 

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The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and use these links to get to the section you want:

 

Developmental biology

| Patterning & signalling

| Morphogenesis & mechanics

| Genes & genomes

| Stem cells, regeneration & disease modelling

| Plant development

Evo-devo & evo

Cell biology

Modelling

Tools & resources

Research practice & education

Why not…

 

 

Developmental biology

| Patterning & signalling

In vivo lineage conversion of vertebrate muscle into early endoderm-like cells
Clyde Campbell, Joseph J. Lancman, Raquel Espin Palazon, Jonatan Matalonga, Jiaye He, Alyssa Graves, Xin-Xin I. Zeng, Rashmi Mishra, Jan Huisken, David Traver, P. Duc Si Dong

 

Emergence and patterning dynamics of mouse definitive endoderm
Maayan Pour, Abhishek Sampath Kumar, Maria Walther, Lars Wittler, Alexander Meissner, Iftach Nachman

 

A Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation
Alexander Guzzetta, Mervenaz Koska, Megan Rowton, Junghun Kweon, Hunter Hidalgo, Heather Eckhart, Rebecca Back, Stephanie Lozano, Anne M. Moon, Anindita Basu, Michael Bressan, Sebastian Pott, Ivan P. Moskowitz

 

The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components
Machiko Teramoto, Ryo Sugawara, Katsura Minegishi, Masanori Uchikawa, Tatsuya Takemoto, Atsushi Kuroiwa, Yasuo Ishii, Hisato Kondoh

 

NRL- and CRX-guided gene network modulates photoreceptor presynapse size and positioning during retinal development
D. Thad Whitaker, Anupam K. Mondal, Hannah Fann, Passley Hargrove, Matthew J. Brooks, Vijender Chaitankar, Wenhan Yu, Zhijian Wu, Soo-Young Kim, Anand Swaroop

 

 

Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal
Koray D. Kaya, Holly Y. Chen, Matthew J. Brooks, Ryan A. Kelley, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Charles T. Drinnan, Linn Gieser, Kamil Kruczek, Slaven Erceg, Tiansen Li, Dunja Lukovic, Yogita K. Adlakha, Emily Welby, Anand Swaroop

 

Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migration
Ed Zandro M. Taroc, Ankana Naik, Jennifer M. Lin, Nicolas B. Peterson, David L. Keefe Jr., Elizabet Genis, Gabriele Fuchs, Ravikumar Balasubramanian, Paolo E. Forni

 

 

GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling
Rachel K. Lex, Zhicheng Ji, Kristin N. Falkenstein, Weiqiang Zhou, Joanna L. Henry, Hongkai Ji, Steven A. Vokes

 

A SMAD1/5-YAP signaling module drives radial glial cell expansion and growth of the developing cerebral cortex
Sonia Najas, Isabel Pijuan, Anna Esteve-Codina, Susana Usieto, Juan D. Martinez, An Zwijsen, Mariona L. Arbonés, Elisa Martí, Gwenvael Le Dréau

 

Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy
Taren Ong, Niraj Trivedi, Randall Wakefield, Sharon Frase, David J. Solecki

 

 

Modulation of β-catenin levels is critical for cranial neural crest patterning and dispersal into first pharyngeal arch
Alok Javali, Vairavan Laxmanan, Dasaradhi Palakodeti, Ramkumar Sambasivan

 

 

Early neuronal processes interact with glia to establish a scaffold for orderly innervation of the cochlea
Noah R Druckenbrod, Evan B Hale, Olubusola O Olukoya, Wynn E Shatzer, Lisa V Goodrich

 

Directed robust generation of functional retinal ganglion cells from Müller glia
Dongchang Xiao, Suo Qiu, Xiuting Huang, Rong Zhang, Qiannan Lei, Wanjing Huang, Haiqiao Chen, Bin Gou, Xiaoxiu Tie, Sheng Liu, Yizhi Liu, Kangxin Jin, Mengqing Xiang

 

NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina
Isabella Palazzo, Kyle Deistler, Thanh V. Hoang, Seth Blackshaw, Andy J. Fischer

 

Multipotent radial glia progenitors and fate-restricted intermediate progenitors sequentially generate diverse cortical interneuron types
Sean M. Kelly, Ricardo Raudales, Monika Moissidis, Gukham Kim, Z. Josh Huang

 

Experience-dependent structural plasticity at pre- and postsynaptic sites of layer 2/3 cells in developing visual cortex
Yujiao Jennifer Sun, J. Sebastian Espinosa, Mahmood S. Hoseini, Michael P. Stryker

 

Sex differences in maturation and attrition rate of adult born neurons in the hippocampus of rats
Shunya Yagi, Jared E.J. Splinter, Daria Tai, Sarah Wong, Liisa A.M. Galea

 

Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis
Stephanie Fore, Mehmet Ilyas Cosacak, Carmen Diaz Verdugo, Caghan Kizil, Emre Yaksi

 

LSD1-mediated enhancer silencing enables endocrine cell development through attenuation of retinoic acid signalling
Nicholas K. Vinckier, Nisha A. Patel, Allen Wang, Jinzhao Wang, Hung-Ping Shih, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Maike Sander

 

CYLD, a Mechanosensitive Deubiquitinase, Regulates TGFβ Signaling in Load-Induced Bone Formation
Jacqueline Nguyen, Ramin Massoumi, Tamara Alliston

 

 

Chemokine receptors CCR1 and ACKR2 coordinate mammary gland development
Gillian J Wilson, Ayumi Fukuoka, Samantha R Love, Jiwon Kim, Marieke Pingen, Alan J Hayes, Gerry Graham

 

Essential role of Bone morphogenetic protein 15 in porcine ovarian and follicular development and ovulation
Yufeng Qin, Tao Tang, Wei Li, Zhiguo Liu, Xiaoliang Yang, Xuan Shi, Guanjie Sun, Xiaofeng Liu, Min Wang, Xinyu Liang, Peiqing Cong, Delin Mo, Xiaohong Liu, Yaosheng Chen, Zuyong He

 

Neural tube development depends on notochord-derived Sonic hedgehog released into the sclerotome
Nitza Kahane, Chaya Kalcheim

 

Hedgehog signaling regulates neurogenesis in the larval and adult zebrafish hypothalamus
Ira Male, A. Tuba Ozacar, Rita R. Fagan, Matthew Loring, Meng-Chieh Shen, Veronica Pace, Chris Devine, Alyssa Lutservitz, Rolf O. Karlstrom

 

 

Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain
Jonathan M. Werner, Maraki Y. Negesse, Dominique L. Brooks, Allyson R. Caldwell, Jafira M. Johnson, Rachel Brewster

 

Smad4 signaling establishes the somatosensory map of basal vomeronasal sensory neurons
Ankana S. Naik, Jennifer M. Lin, Ed Zandro M. Taroc, Raghu R. Katreddi, Jesus A. Frias, Morgan Sammons, Paolo E. Forni

 

Crumbs2 mediates ventricular layer remodelling to form the adult spinal cord central canal
Christine Tait, Kavitha Chinnaiya, Mariyam Murtaza, John-Paul Ashton, Nicholas Furley, Chris J. Hill, C Henrique Alves, Jan Wijnholds, Kai S. Erdmann, Raman M. Das, Penny Rashbass, Kate G. Storey, Marysia Placzek

 

Haploinsufficient maternal effect of Epidermal Growth Factor Receptor A mutation in zebrafish
Margherita Ciano, Paul R. Kemp, S. Amanda Sathyapala, Simon M. Hughes

 

Developmental stage-specific distribution of macrophages in mouse mammary gland
Teneale A. Stewart, Katherine Hughes, David A. Hume, Felicity M. Davis

 

 

Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation
Ranjith Viswanathan, Aleksandar Necakov, Mateusz Trylinski, Rohit Krishnan Harish, Daniel Krueger, Emilia Esposito, Francois Schweisguth, Pierre Neveu, Stefano De Renzis

 

BMP-signalling inhibition in Drosophila secondary cells remodels the seminal proteome, and self and rival ejaculate functions
Ben R. Hopkins, Irem Sepil, Sarah Bonham, Thomas Miller, Philip D. Charles, Roman Fischer, Benedikt M. Kessler, Clive Wilson, Stuart Wigby

 

Notch signaling coordinates ommatidial rotation in the Drosophila eye via transcriptional regulation of the EGF-Receptor ligand Argos
Yildiz Koca, Benjamin E. Housden, William J. Gault, Sarah J. Bray, Marek Mlodzik

 

Constraints and limitations on decoding positional information: the Bicoid case-study
Huy Tran, Aleksandra M. Walczak, Nathalie Dostatni

 

Shuttling of Dorsal by Cactus: mechanism and implications
Allison E. Schloop, Sophia Carrell-Noel, Gregory T. Reeves

 

Robustness of the Dorsal morphogen gradient with respect to morphogen dosage
Hadel Y. Al Asafen, Prasad U. Bandodkar, Sophia Carrell-Noel, Gregory T. Reeves

 

 

Caspase-dependent activation of Hedgehog-signalling sustains proliferation and differentiation of ovarian somatic stem cells
Alessia Galasso, Daria Iakovleva, Luis Alberto Baena-Lopez

 

A Canal-Associated Neuron cAMP signalling pathway that regulates C. elegans larval development
Jason Chien, Fred W. Wolf, Sarah Grosche, Nebeyu Yosef, Gian Garriga, Catarina Mörck

 

 

| Morphogenesis & mechanics

The plakin domain of C. elegans VAB-10/plectin acts as a hub in a mechanotransduction pathway to promote morphogenesis
Shashi Kumar Suman, Csaba Daday, Teresa Ferraro, Thanh Vuong-Brender, Saurabh Tak, Sophie Quintin, François Robin, Frauke Gräter, Michel Labouesse

 

 

Mechanical Feedback and Robustness of Apical Constrictions in Drosophila Embryo Ventral Furrow Formation
Michael C. Holcomb, Guo-Jie Jason Gao, Mahsa Servati, Dylan Schneider, Presley K. McNeely, Jeffrey H. Thomas, Jerzy Blawzdziewicz

 

 

Regionalized tissue fluidization by an actomyosin cable is required for epithelial gap closure during insect gastrulation
A. Jain, V. Ulman, A. Mukherjee, M. Prakash, L. Pimpale, S. Muenster, K.A. Panfilio, F. Jug, S.W. Grill, P. Tomancak, A. Pavlopoulos

 

Fascin regulates protrusions and delamination to mediate invasive, collective cell migration in vivo
Maureen C. Lamb, Kelsey K. Anliker, Tina L. Tootle

 

Morphogenesis is transcriptionally coupled to neurogenesis during olfactory placode development
Raphaël Aguillon, Romain Madelaine, Harendra Guturu, Sandra Link, Pascale Dufourcq, Virginie Lecaudey, Gill Bejerano, Patrick Blader, Julie Batut

 

 

Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development
Kristin M. Ates, Tong Wang, Trevor Moreland, Rajalakshmi Veeranan-Karmegam, Priya Anand, Wolfgang Wenzel, Hyung-Goo Kim, Lynne A. Wolfe, Joshi Stephen, David R. Adams, Thomas Markello, Cynthia J. Tifft, William A. Gahl, Graydon B. Gonsalvez, May Christine Malicdan, Heather Flanagan-Steet, Y. Albert Pan

 

The desmosomal cadherin Desmogon is necessary for the structural integrity of the Medaka notochord
Ali Seleit, Karen Groß, Michaela Wölk, Camilla Autorino, Lazaro Centanin, Jasmin Onistschenko

 

mRNA compartmentalisation spatially orients tissue morphogenesis
Guilherme Costa, Joshua Bradbury, Nawseen Tarannum, Shane P. Herbert

 

Cytokinetic abscission dynamics in neuroepithelial stem cells during brain development
Katrina C. McNeely, Jessica Neville Little, Noelle D. Dwyer

 

Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow
Laura Taberner, Aitor Bañón, Berta Alsina

 

Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1
Takehiko Ichikawa, Carsten Stuckenholz, Lance A. Davidson

 

Head Mesoderm Tissue Growth, Dynamics and Neural Crest Cell Migration
Mary Cathleen McKinney, Rebecca McLennan, Rasa Giniunaite, Ruth E. Baker, Philip K. Maini, Hans G. Othmer, Paul M Kulesa

 

ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth
Tingting Ji, Kai Wang, Jiale Fan, Jichang Huang, Mengqing Wang, Xiaohua Dong, Yanjun Shi, Laura Manning, Xumin Zhang, Zhiyong Shao, Daniel A. Colón-Ramos

 

In-silico definition of the Drosophila melanogaster matrisome
Martin N. Davis, Sally Horne-Badovinac, Alexandra Naba

 

The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ precursors in vasculogenesis and primitive hematopoiesis
Sumeda Nandadasa, Anna O’Donnell, Ronald J Midura, Suneel S Apte

 

Mechanically activated Piezo channels modulate outflow tract valve development through Yap1 and Klf2-Notch signaling axis
Anne Laure Duchemin, Hélène Vignes, Julien Vermot

 

| Genes & genomes

 

 

A Single-Cell Transcriptome Atlas for Zebrafish Development
Dylan R. Farnsworth, Lauren Saunders, Adam C. Miller

 

A single cell transcriptome atlas of the developing zebrafish hindbrain
Monica Tambalo, Richard Mitter, David G. Wilkinson

 

A single cell atlas of the developing Drosophila ovary identifies follicle stem cell progenitors
Maija Slaidina, Torsten U. Banisch, Selena Gupta, Ruth Lehmann

 

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation
Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, Oana Kubinyecz, Fátima Santos, Mélanie A. Eckersley-Maslin, Oliver Stegle, Wolf Reik

 

The enteric nervous system of the human and mouse colon at a single-cell resolution
Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, Maria Ericsson, Gabriel K. Griffin, Danielle Dionne, Michael S. Cuoco, Max N. Goder-Reiser, Tatyana Sharova, Andrew J. Aguirre, Genevieve M. Boland, Daniel Graham, Orit Rozenblatt-Rosen, Ramnik J. Xavier, Aviv Regev

 

 

The molecular anatomy of mouse skin during hair growth and rest
Simon Joost, Karl Annusver, Tina Jacob, Xiaoyan Sun, Unnikrishnan Sivan, Tim Dalessandri, Inês Sequeira, Rickard Sandberg, Maria Kasper

 

Development of the Mouse and Human Cochlea at Single Cell Resolution
Kevin Shengyang Yu, Stacey M. Frumm, Jason S. Park, Katharine Lee, Daniel M. Wong, Lauren Byrnes, Sarah M. Knox, Julie B. Sneddon, Aaron D. Tward

 

A molecular cell atlas of the human lung from single cell RNA sequencing
Kyle J. Travaglini, Ahmad N. Nabhan, Lolita Penland, Rahul Sinha, Astrid Gillich, Rene V. Sit, Stephen Chang, Stephanie D. Conley, Yasuo Mori, Jun Seita, Gerald J. Berry, Joseph B. Shrager, Ross J. Metzger, Christin S. Kuo, Norma Neff, Irving L. Weissman, Stephen R. Quake, Mark A. Krasnow

 

Single Cell RNAseq Reveals A Critical Role of Chloride Channels in Airway Development
Mu He, Bing Wu, Daniel D. Le, Wenlei Ye, Adriane W. Sinclair, Valeria Padovano, Yuzhang Chen, Kexin Li, Rene Sit, Michelle Tan, Michael J. Caplan, Norma Neff, Yuh Nung Jan, Spyros Darmanis, Lily Y. Jan

 

Generation of human neural retina transcriptome atlas by single cell RNA sequencing
Samuel W. Lukowski, Camden Y. Lo, Alexei Sharov, Quan H. Nguyen, Lyujie Fang, Sandy S.C. Hung, Ling Zhu, Ting Zhang, Tu Nguyen, Anne Senabouth, Jafar S. Jabbari, Emily Welby, Jane C. Sowden, Hayley S. Waugh, Adrienne Mackey, Graeme Pollock, Trevor D. Lamb, Peng-Yuan Wang, Alex W. Hewitt, Mark Gillies, Joseph E. Powell, Raymond C.B. Wong

 

Single-cell transcriptomics reveals temporal dynamics of critical regulators of germ cell fate during mouse sex determination
Chloé Mayère, Yasmine Neirijnck, Pauline Sararols, Isabelle Stévant, Françoise Kühne, Anne Amandine Chassot, Marie-Christine Chaboissier, Emmanouil T. Dermitzakis, Serge Nef

 

Integrated single-cell transcriptomics and chromatin accessibility analysis reveals novel regulators of mammary epithelial cell identity
Nicholas Pervolarakis, Quy Nguyen, Guadalupe Gutierrez, Peng Sun, Darisha Jhutty, Grace XY Zheng, Corey M Nemec, Xing Dai, Kazuhide Watanabe, Kai Kessenbrock

 

The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice
Sumantra Chatterjee, Priyanka Nandakumar, Dallas R. Auer, Stacey B. Gabriel, Aravinda Chakravarti

 

Developmental gene expression differences between humans and mammalian models
Margarida Cardoso-Moreira, Britta Velten, Matthew Mort, David N. Cooper, Wolfgang Huber, Henrik Kaessmann

 

Transcriptional control of cardiac neural crest cells condensation and outflow tract septation by the Smad1/5/8 inhibitor Dullard
Jean-François Darrigrand, Mariana Valente, Pauline Martinez, Glenda Comai, Maxime Petit, Ryuichi Nishinakamura, Daniel S. Osorio, Vanessa Ribes, Bruno Cadot

 

MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation in Mice
Fan Zhao, Xiaoli Ma, Wuxia Qiu, Pai Wang, Ru Zhang, Zhihao Chen, Peihong Su, Yan Zhang, Dijie Li, Jianhua Ma, Chaofei Yang, Lei Chen, Chong Yin, Ye Tian, Lifang Hu, Yu Li, Ge Zhang, Xiaoyang Wu, Airong Qian

 

MIR3607 regulates cerebral cortex development via activation of Wnt/βCat signaling
Kaviya Chinnappa, Ángel Márquez-Galera, Anna Prieto-Colomina, Yuki Nomura, Adrián Cárdenas, José P. López-Atalaya, Víctor Borrell

 

The homeoprotein ENGRAILED-1 promotes motoneuron survival and sustains motor functions
Stephanie E. Vargas Abonce, Mélanie Lebœuf, Kenneth L. Moya, Alain Prochiantz

 

Role of the imprinted allele of the p57Kip2 gene in mouse neocortical development
Yui Imaizumi, Shohei Furutachi, Tomoyuki Watanabe, Hiroaki Miya, Daichi Kawaguchi, Yukiko Gotoh

 

 

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4
Andrew M Garrett, Peter J Bosch, David M Steffen, Leah C Fuller, Charles G Marcucci, Alexis A Koch, Preeti Bais, Joshua A Weiner, Robert W Burgess

 

The transcription factor E2A drives neural differentiation in pluripotent cells
Chandrika Rao, Mattias Malaguti, John O. Mason, Sally Lowell

 

DUX4 regulates oocyte to embryo transition in human
Sanna Vuoristo, Christel Hydén-Granskog, Masahito Yoshihara, Lisa Gawriyski, Anastassius Damdimopoulos, Shruti Bhagat, Kosuke Hashimoto, Kaarel Krjutškov, Sini Ezer, Priit Paluoja, Karolina Lundin, Pauliina Paloviita, Gaëlle Recher, Vipin Ranga, Tomi Airenne, Mahlet Tamirat, Eeva-Mari Jouhilahti, Timo Otonkoski, Juha S. Tapanainen, Hideya Kawaji, Yasuhiro Murakawa, Thomas R. Bürglin, Markku Varjosalo, Mark S. Johnson, Timo Tuuri, Shintaro Katayama, Juha Kere

 

Developmental Genome-Wide DNA Methylation Asymmetry Between Mouse Placenta and Embryo
LM Legault, K Doiron, A Lemieux, M Caron, D Chan, FL Lopes, G Bourque, D Sinnett, S McGraw

 

Cables2 Is a Novel Smad2-Regulatory Factor Essential for Early Embryonic Development in Mice
Tra Thi Huong Dinh, Hiroyoshi Iseki, Seiya Mizuno, Saori Iijima-Mizuno, Yoko Tanimoto, Yoko Daitoku, Kanako Kato, Yuko Hamada, Ammar Shaker Hamed Hasan, Hayate Suzuki, Kazuya Murata, Masafumi Muratani, Masatsugu Ema, Jun-dal Kim, Junji Ishida, Akiyoshi Fukamizu, Mitsuyasu Kato, Satoru Takahashi, Ken-ichi Yagami, Valerie Wilson, Ruth M. Arkell, Fumihiro Sugiyama

 

Nf1 deletion results in depletion of the Lhx6 transcription factor and a specific loss of parvalbumin+ cortical interneurons
Kartik Angara, Emily Ling-Lin Pai, Stephanie M Bilinovich, April M Stafford, Julie T Nguyen, Anirban Paul, John L Rubenstein, Daniel Vogt

 

Screening and identification of MicroRNAs expressed in perirenal adipose tissue during rabbit growth
Guoze Wang, Guo Guo, Xueting Tian, Shenqiang Hu, Kun Du, Jingxin Mao, Xianbo Jia, Shiyi Chen, Jie Wang, Songjia Lai

 

Developmental regulation of Canonical and small ORF translation from mRNA
Pedro Patraquim, Jose I. Pueyo, M. Ali Mumtaz, Julie Aspden, J.P. Couso

 

Identification of genes involved in the differentiation of R7y and R7p photoreceptor cells in Drosophila
James B Earl, Lauren A Vanderlinden, Laura M Saba, Steven G Britt

 

Low Affinity Binding Sites in an Activating CRM Mediate Negative Autoregulation of the Drosophila Hox Gene Ultrabithorax
Rebecca K Delker, Vikram Ranade, Ryan Loker, Roumen Voutev, Richard S Mann

 

Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism
Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Joseph Salomone, Ian Campbell, FearGod V. Okwubido-Williams, Matthew R. Hass, Natanel Eafergan, Kenneth H. Moberg, Rhett A. Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein

 

The Impact of Genetic Background and Cell Lineage on the Level and Pattern of Position Effect Variegation
Sidney H. Wang, Sarah C.R. Elgin

 

 

Reduced function of the RNA export factor, Nxt1, in Drosophila causes muscle degeneration and lowers expression of genes with long introns and circular RNA
Kevin van der Graaf, Katia Jindrich, Robert Mitchell, Helen White-Cooper

 

Dynamics of activating and repressive histone modifications in Drosophila neural stem cell lineages and brain tumors
Merve Deniz Abdusselamoglu, Lisa Landskron, Sarah K. Bowman, Elif Eroglu, Thomas Burkard, Robert E. Kingston, Juergen A. Knoblich

 

 

| Stem cells, regeneration & disease modelling

Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability
Tamsin J Samuels, Aino I Järvelin, David Ish-Horowicz, Ilan Davis

 

IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis
Alexei Arnaoutov, Hangnoh Lee, Karen Plevock Haase, Vasilisa Aksenova, Michal Jarnik, Brian Oliver, Mihaela Serpe, Mary Dasso

 

Ureteric Bud Cells Programmed from Embryonic Stem Cells Obtain Competence for Secondary Induction in the Kidney
Zenglai Tan, Aleksandra Rak-Raszewska, Ilya Skovorodkin, Seppo J. Vainio

 

Release of stem cells from quiescence reveals multiple gliogenic domains in the adult brain
Ana C. Delgado, Angel R. Maldonado-Soto, Violeta Silva-Vargas, Dogukan Mizrak, Thomas von Känel, Alex Paul, Aviv Madar, Henar Cuervo, Jan Kitajewski, Chyuan-Sheng Lin, Fiona Doetsch

 

CHD8 regulates the balance between proliferation and differentiation of human iPSCs in neural development
Wenzhong Liu, Weilai Dong, Ellen J. Hoffman, Thomas V. Fernandez, Abha R. Gupta

 

Aging induces aberrant state transition kinetics in murine muscle stem cells
Jacob C. Kimmel, Ara B. Hwang, Wallace F. Marshall, Andrew S. Brack

 

Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm
Adam Stevens, Helen Smith, Terence Garner, Ben Minogue, Sharon Sneddon, Lisa Shaw, Maria Keramari, Rachel Oldershaw, Nicola Bates, Daniel R Brison, Susan J Kimber

 

Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of mouse hematopoietic cells
Ross C. Hardison, Yu Zhang, Cheryl A. Keller, Guanjue Xiang, Elisabeth Heuston, Lin An, Jens Lichtenberg, Belinda M. Giardine, David Bodine, Shaun Mahony, Qunhua Li, Feng Yue, Mitchell J. Weiss, Gerd Blobel, James Taylor, Jim Hughes, Doug Higgs, Berthold Gottgens

 

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis
Guanjue Xiang, Cheryl A. Keller, Elisabeth Heuston, Belinda M. Giardine, Lin An, Alexander Q. Wixom, Amber Miller, April Cockburn, Jens Lichtenberg, Berthold Göttgens, Qunhua Li, David Bodine, Shaun Mahony, James Taylor, Gerd A. Blobel, Mitchell J. Weiss, Yong Cheng, Feng Yue, Jim Hughes, Douglas R. Higgs, Yu Zhang, Ross C. Hardison

 

Single-cell tracing of the first hematopoietic stem cell generation in human embryos
Yang Zeng, Jian He, Zhijie Bai, Zongcheng Li, Yandong Gong, Chen Liu, Yanli Ni, Junjie Du, Chunyu Ma, Lihong Bian, Yu Lan, Bing Liu

 

Proliferative behavior of hematopoietic stem cells revisited: No evidence for mitotic memory
Mina N. F. Morcos, Thomas Zerjatke, Ingmar Glauche, Clara M. Munz, Yan Ge, Andreas Petzold, Susanne Reinhardt, Andreas Dahl, Natasha Anstee, Ruzhica Bogeska, Michael Milsom, Petter Säwén, Haixia Wan, David Bryder, Axel Roers, Alexander Gerbaulet

 

Function of Pumilio Genes in Human Embryonic Stem Cells and Their Effect in Stemness and Cardiomyogenesis
Isabelle Leticia Zaboroski Silva, Anny Waloski Robert, Guillermo Cabrera Cabo, Lucia Spangenberg, Marco Augusto Stimamiglio, Bruno Dallagiovanna, Daniela Fiori Gradia, Patrícia Shigunov

 

NCOR1 and OCT4 Facilitate Early Reprogramming by Co-Suppressing Fibroblast Gene Expression
Georgina Peñalosa-Ruiz, Klaas W. Mulder, Gert Jan C. Veenstra

 

Distinct features of nucleolus-associated domains in mouse embryonic stem cells
Aizhan Bizhanova, Aimin Yan, Jun Yu, Lihua Julie Zhu, Paul D. Kaufman

 

Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production
Ningbo Wu, Hongxiang Sun, Xiaoyun Zhao, Lei Chen, Yuanyuan Qi, Yuheng Han, Xianan Liu, Caixia Gao, Qun Wang, Lingjuan He, Xiaoyin Niu, Zhiduo Liu, Hua-Bing Li, Yi Arial Zeng, Manolis Roulis, Dou Liu, Zhengfeng Yang, Bin Zhou, Richard A. Flavell, Bing Su

 

Short and long TNF-alpha exposure recapitulates canonical astrogliosis events in human induced pluripotent stem cells-derived astrocytes
Pablo Trindade, Erick Correia Loiola, Juciano Gasparotto, Camila Tiefensee Ribeiro, Pablo Leal Cardozo, Sylvie Devalle, José Alexandre Salerno, Isis Moraes Ornelas, Pitia Flores Ledur, Fabiola Mara Ribeiro, Ana Lucia Marques Ventura, José Claudio Fonseca Moreira, Daniel Pens Gelain, Lisiane Oliveira Porciúncula, Stevens Kastrup Rehen

 

 

Ephrin-B1 blocks adult cardiomyocyte proliferation and heart regeneration
Marie Cauquil, Céline Mias, Céline Guilbeau-Frugier, Clément Karsenty, Marie-Hélène Seguelas, Gaël Genet, Edith Renaud-Gabardos, Anne-Catherine Prats, Véronique Pons, Maxime Branchereau, Christophe Heymes, Denis Calise, Olivier Lairez, Danièle Daviaud, Benjamin Honton, Céline Frongia, Bernard Ducommun, Marie-Bernadette Delisle, Dina N. Arvanitis, Atul Pathak, Jean-Michel Sénard, Céline Galés

 

 

Regenerative neurogenesis is induced from glia by Ia-2 driven neuron-glia communication
Neale Harrison, Elizabeth Connolly, Alicia Gascón Gubieda, Zidan Yang, Benjamin Altenhein, Maria Losada-Perez, Marta Moreira, Alicia Hidalgo

 

ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration
Vanisha Lakhina, Melanie McReynolds, Daniel T. Grimes, Joshua D. Rabinowitz, Rebecca D. Burdine, Coleen T. Murphy

 

Signaling gradients in surface dynamics as basis for planarian regeneration
Arnd Scheel, Angela Stevens, Christoph Tenbrock

 

TRiC activates the unfolded protein response and protects starved stem cells by modulating energy and lipid metabolism during planarian regeneration
Óscar Gutiérrez-Gutiérrez, Daniel A. Felix, Alessandra Salvetti, Anne Thems, Stefan Pietsch, Andreas Koeberle, K. Lenhard Rudolph, Cristina González-Estévez

 

Cellular heterogeneity and lineage restriction during mouse digit tip regeneration at single cell resolution
Gemma L. Johnson, Erick J. Masias, Jessica A. Lehoczky

 

Regeneration in the absence of a blastema requires cell division but is not tied to wound healing in the ctenophore Mnemiopsis leidyi
Julia Ramon-Mateu, Tori Ellison, Thomas E. Angelini, Mark Q. Martindale

 

Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors
Sumona P. Dhara, Andrea Rau, Michael J. Flister, Nicole M. Recka, Michael D. Laiosa, Paul L. Auer, Ava J. Udvadia

 

Transcriptional profiling of non-injured nociceptors after spinal cord injury reveals diverse molecular changes
Jessica R. Yasko, Isaac L. Moss, Richard E. Mains

 

Catecholaminergic axons in the neocortex of adult mice regrow following brain injury
Sarah E. Dougherty, Tymoteusz J. Kajstura, Yunju Jin, Michelle H. Chan-Cortés, Akhil Kota, David J. Linden

 

Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment
Virginie Mournetas, Emmanuelle Massouridès, Jean-Baptiste Dupont, Etienne Kornobis, Hélène Polvèche, Margot Jarrige, Maxime Gosselin, Spiros D. Garbis, Dariusz C. Górecki, Christian Pinset

 

Primary cilia deficiency in neural crest cells causes Anterior Segment Dysgenesis
Céline Portal, Peter Lwigale, Panteleimon Rompolas, Carlo Iomini

 

Hyperactive MEK1 signaling in cortical GABAergic interneurons causes embryonic parvalbumin-neuron death and deficits in behavioral inhibition
Michael C. Holter, Lauren T. Hewitt, Kenji J. Nishimura, George R. Bjorklund, Shiv Shah, Noah R. Fry, Katherina P. Rees, Tanya A. Gupta, Carter W. Daniels, Guohui Li, Steven Marsh, David M. Treiman, M. Foster Olive, Trent R. Anderson, Federico Sanabria, William D. Snider, Jason M. Newbern

 

Human cerebral organoids capture the spatiotemporal complexity and disease dynamics of UBE3A
Dilara Sen, Alexis Voulgaropoulos, Zuzana Drobna, Albert J. Keung

 

 

Modeling and treating GRIN2A developmental and epileptic encephalopathy in mice
Ariadna Amador, Christopher D. Bostick, Heather Olson, Jurrian Peters, Chad R. Camp, Daniel Krizay, Wenjuan Chen, Wei Han, Weiting Tang, Ayla Kanber, Sukhan Kim, Jia Jie Teoh, Sabrina Petri, Hunki Paek, Ana Kim, Cathleen M. Lutz, Mu Yang, Scott J. Myers, Subhrajit Bhattacharya, Hongjie Yuan, David B. Goldstein, Annapurna Poduri, Michael J. Boland, Stephen F. Traynelis, Wayne N. Frankel

 

scribble abrogation induces tumor growth through JNK-Wnt pathways depending on cellular-microenvironment in Drosophila wing imaginal tissue
Amarish Kumar Yadav, Roshan Fatima, Saripella Srikrishna

 

| Plant development

Dual function of HYPONASTIC LEAVES 1 during early skotomorphogenic growth in Arabidopsis
Juan Manuel Sacnun, Roberta Crespo, Javier Palatnik, Rodolfo Rasia, Nahuel González-Schain

 

 

PDK1 has a pleiotropic PINOID-independent role in Arabidopsis development
Yao Xiao, Remko Offringa

 

Auxin-induced nanoclustering of membrane signaling complexes underlies cell polarity establishment in Arabidopsis
Xue Pan, Linjing Fang, Jianfeng Liu, Betul Senay-Aras, Wenwei Lin, Shuan Zheng, Tong Zhang, Uri Manor, Weitao Chen, Zhenbiao Yang

 

Coordination of Tissue Cell Polarity by Auxin Transport and Signaling
Carla Verna, Sree Janani Ravichandran, Megan G. Sawchuk, Nguyen Manh Linh, Enrico Scarpella

 

Sugar availability suppresses the auxin-induced strigolactone pathway to promote bud outgrowth
Jessica Bertheloot, François Barbier, Frédéric Boudon, Maria Dolores Perez-Garcia, Thomas Péron, Sylvie Citerne, Elizabeth Dun, Christine Beveridge, Christophe Godin, Soulaiman Sakr

 

Trehalose 6-phosphate Controls Seed Filling by Inducing Auxin Biosynthesis
Tobias Meitzel, Ruslana Radchuk, Erin L. McAdam, Ina Thormählen, Regina Feil, Eberhard Munz, Alexander Hilo, Peter Geigenberger, John J. Ross, John E. Lunn, Ljudmilla Borisjuk

 

Arabidopsis ERF109 regulates auxin transport-related genes in root development
Rui Liu, Xiao-Teng Cai, Ping-Xia Zhao, Ping Xu, Cheng-Bin Xiang

 

Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells
Eleazar Rodriguez, Jonathan Chevalier, Jakob Olsen, Jeppe Ansbøl, Vaitsa Kapousidou, Zhangli Zuo, Steingrim Svenning, Christian Loefke, Stefanie Koemeda, Pedro Serrano Drozdowskyj, Jakub Jez, Gerhard Durnberger, Fabian Kuenzl, Michael Schutzbier, Karl Mechtler, Signe Lolle, Yasin Dagdas, Morten Petersen

 

Integrated Multi-omic Framework of the Plant Response to Jasmonic Acid
Mark Zander, Mathew G. Lewsey, Natalie M. Clark, Lingling Yin, Anna Bartlett, J. Paola Saldierna Guzmán, Elizabeth Hann, Amber E. Langford, Bruce Jow, Aaron Wise, Joseph R. Nery, Huaming Chen, Ziv Bar-Joseph, Justin W. Walley, Roberto Solano, Joseph R. Ecker

 

Cut and paste – Efficient cotyledon micrografting for Arabidopsis thaliana seedlings
Kai Bartusch, Jana Trenner, Marcel Quint

 

Identification of nitrogen-dependent QTL and underlying genes for root system architecture in hexaploid wheat
Marcus Griffiths, Jonathan A. Atkinson, Laura-Jayne Gardiner, Ranjan Swarup, Michael P. Pound, Michael H. Wilson, Malcolm J. Bennett, Darren M. Wells

 

The maize Hairy Sheath Frayed1 (Hsf1) mutant alters leaf patterning through increased cytokinin signaling
Michael G. Muszynski, Lindsay Moss-Taylor, Sivanandan Chudalayandi, James Cahill, Angel R. Del Valle-Echevarria, Ignacio Alvarez, Abby Petefish, Nobue Makita, Hitoshi Sakakibara, Dmitry M. Krivosheev, Sergey N. Lomin, Georgy A. Romanov, Subbiah Thamotharan, Thao Dam, Bailin Li, Norbert Brugière

 

Natural genetic variation underlying tiller development in barley (Hordeum vulgare L)
Allison M. Haaning, Kevin P. Smith, Gina L. Brown-Guedira, Shiaoman Chao, Priyanka Tyagi, Gary J. Muehlbauer

 

 

NbCycB2 represses Nbwo activity via a negative feedback loop in the tobacco trichome developmemt
Minliang Wu, Yuchao Cui, Li Ge, Lipeng Cui, Zhichao Xu, Hongying Zhang, Zhaojun Wang, Dan Zhou, Shuang Wu, Liang Chen, Hong Cui

 

Genome-wide analysis of GATA factors in moso bamboo (Phyllostachys edulis) unveils that PeGATAs regulate shoot rapid-growth and rhizome development
Taotao Wang, Yong Yang, Shuaitong Lou, Wei Wei, Zhixin Zhao, Chentao Lin, Liuyin Ma

 

Temperature dependent sex-biased gene expression in the gametophytes of the kelp Saccharina latissima
Cátia Monteiro, Sandra Heinrich, Inka Bartsch, Klaus Ulrich Valentin, Erwan Corre, Jonas Collén, Lars Harms, Gernot Glöckner, Kai Bischof

 

Developing a rapid and highly efficient cowpea regeneration and transformation system using embryonic axis explants
Ping Che, Shujun Chang, Marissa K. Simon, Zhifen Zhang, Ahmed Shaharyar, Jesse Ourada, Dennis O’Neill, Mijael Torres-Mendoza, Yinping Guo, Kathleen M. Marasigan, Jean-Philippe Vielle-Calzada, Peggy Ozias-Akins, Marc C. Albertsen, Todd J. Jones

 

Evo-devo & evo

 

 

 

Interspecies transcriptome analyses identify genes that control the development and evolution of limb skeletal proportion
Aditya Saxena, Virag Sharma, Mai P Tran, Haydee L Gutierrez, Joel M Erberich, Amanda Birmingham, Michael Hiller, Kimberly L Cooper

 

Mosaic heterochrony in neural progenitors sustains accelerated brain growth and neurogenesis in the juvenile killifish N. furzeri
Marion Coolen, Miriam Labusch, Abdelkrim Mannioui, Beate Hoppe, Mario Baumgart, Laure Bally-Cuif

 

Characterization of neurogenic niches in the telencephalon of juvenile and adult sharks
A Docampo-Seara, S Pereira-Guldrís, N Sánchez-Farías, S Mazan, MA Rodríguez, E Candal

 

Evolved differences in cis and trans regulation between the maternal and zygotic mRNA complements in the Drosophila embryo
Emily L. Cartwright, Susan E. Lott

 

PIWI-piRNA pathway-mediated transposable element repression in Hydra somatic stem cells
Bryan B. Teefy, Stefan Siebert, Jack F. Cazet, Haifan Lin, Celina E. Juliano

 

 

Chytrid rhizoid morphogenesis is adaptive and resembles hyphal development in ‘higher’ fungi
Davis Laundon, Nathan Chrismas, Glen Wheeler, Michael Cunliffe

 

Laboratory biases hinder Eco-Evo-Devo integration: hints from the microworld
Natsuko Rivera-Yoshida, Alejandra Hernandez-Teran, Ana E. Escalante, Mariana Benitez

 

The crustacean Armadillidium vulgare, a new promising model for the study of cellular senescence
Charlotte Depeux, Ascel Samba-Louaka, Thomas Becking, Christine Braquart-Varnier, Jérôme Moreau, Jean-François Lemaître, Tiffany Laverre, Hélène Paulhac, François-Xavier Dechaume-Moncharmont, Jean-Michel Gaillard, Sophie Beltran-Bech

 

Mutation accumulation in chromosomal inversions maintains wing pattern polymorphism in a butterfly
Paul Jay, Mathieu Chouteau, Annabel Whibley, Héloïse Bastide, Violaine Llaurens, Hugues Parrinello, Mathieu Joron

 

A chronology of multicellularity evolution in cyanobacteria
Katrin Hammerschmidt, Giddy Landan, Fernando Domingues Kümmel Tria, Tal Dagan

 

Evolution of imprinting via lineage-specific insertion of retroviral promoters
Aaron B. Bogutz, Julie Brind’Amour, Hisato Kobayashi, Kristoffer N. Jensen, Kazuhiko Nakabayashi, Hiroo Imai, Matthew C. Lorincz, Louis Lefebvre

 

 

Cell biology

Isolation of an archaeon at the prokaryote-eukaryote interface
Hiroyuki Imachi, Masaru K. Nobu, Nozomi Nakahara, Yuki Morono, Miyuki Ogawara, Yoshihiro Takaki, Yoshinori Takano, Katsuyuki Uematsu, Tetsuro Ikuta, Motoo Ito, Yohei Matsui, Masayuki Miyazaki, Kazuyoshi Murata, Yumi Saito, Sanae Sakai, Chihong Song, Eiji Tasumi, Yuko Yamanaka, Takashi Yamaguchi, Yoichi Kamagata, Hideyuki Tamaki, Ken Takai

 

 

Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
Adriana Golding, Ilaria Visco, Peter Bieling, William Bement

 

Transient primary cilia mediate robust Hedgehog pathway-dependent cell cycle control
Emily K. Ho, Anaïs E. Tsai, Tim Stearns

 

Recruitment of mRNAs to P granules by gelation with intrinsically-disordered proteins
Chih-Yung S. Lee, Andrea Putnam, Tu Lu, Shuaixin He, John Paul T. Ouyang, Geraldine Seydoux

 

Chemotaxis and topotaxis add vectorially for amoeboid cell migration
Joeri A. J. Wondergem, Maria Mytiliniou, Falko C. H. de Wit, Thom G. A. Reuvers, David Holcman, Doris Heinrich

 

 

In vivo characterisation of endogenous cardiovascular extracellular vesicles in larval and adult zebrafish
Aaron Scott, Lorena Sueiro Ballesteros, Marston Bradshaw, Ann Power, John Love, Danielle Paul, Andrew Herman, Costanza Emanueli, Rebecca J. Richardson

 

Cep97 Is Required For Centriole Structural Integrity And Cilia Formation In Drosophila
Jeroen Dobbelaere, Marketa Schmidt-Cernohorska, Martina Huranova, Dea Slade, Alexander Dammermann

 

A G1 sizer mechanism coordinates growth and division in the mouse epidermis
Shicong Xie, Jan M Skotheim

 

Traction forces control cell-edge dynamics and mediate distance-sensitivity during cell polarization
Zeno Messi, Alicia Bornert, Franck Raynaud, Alexander Verkhovsky

 

Cell culture dimensionality influences mesenchymal stem cell fate through cadherin-2 and cadherin-11
Fiona R Passanha, Thomas Geuens, Simon Konig, Clemens A van Blitterswijk, Vanessa LS LaPointe

 

Intra-Nuclear Tensile Strain Mediates Reorganization of Epigenetically Marked Chromatin During Cardiac Development and Disease
Benjamin Seelbinder, Soham Ghosh, Alycia G. Berman, Stephanie E. Schneider, Craig J. Goergen, Sarah Calve, Corey P. Neu

 

The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells
Andrea Haag, Michael Walser, Adrian Henggeler, Alex Hajnal

 

LINC complexes are mechanotransducers that discriminate Epithelial-Mesenchymal Transition programs
Théophile Déjardin, Pietro Salvatore Carollo, Patricia M. Davidson, Cynthia Seiler, Damien Cuvelier, Bruno Cadot, Cecile Sykes, Edgar R. Gomes, Nicolas Borghi

 

Live cell imaging of nuclear actin filaments and heterochromatic repair foci in Drosophila and mouse cells
Colby See​, Deepak Arya​, Emily Lin, Irene Chiolo​

 

Radial contractility of Actomyosin-II rings facilitates cargo trafficking and maintains axonal structural stability following cargo-induced transient axonal expansion
Tong Wang, Wei Li, Sally Martin, Andreas Papadopulos, Anmin Jiang, Golnoosh Shamsollahi, Rumelo Amor, Vanessa Lanoue, Pranesh Padmanabhan, Frederic A. Meunier

 

mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation
Yuqi Zhang, Krista M. Pettee, Kathryn N. Becker, Kathryn M. Eisenmann

 

Modelling

Reconstruction of the phase dynamics of the somitogenesis clock oscillator
Lucas J. Morales Moya, J. Kim Dale, Philip J. Murray

 

A geometry-based model describes lumen stability in epithelial cells
Claudia G. Vasquez, Vipul T. Vachharajani, Carlos Garzon-Coral, Alexander R. Dunn

 

Signaling gradients in surface dynamics as basis for planarian regeneration
Arnd Scheel, Angela Stevens, Christoph Tenbrock

 

A simple model for pattern formation in clonal-growth plants
Daniel Ruiz-Reynés, Francesca Schönsberg, Emilio Hernández-García, Damià Gomila

 

Swarm Intelligence for Morphogenetic Engineering
Bruce J. MacLennan, Allen C. McBride

 

Model to link cell shape and polarity with organogenesis
Bjarke Frost Nielsen, Silas Boye Nissen, Kim Sneppen, Ala Trusina, Joachim Mathiesen

 

The basal level of gene expression associated with chromatin loosening shapes Waddington landscapes and controls cell differentiation
Gilles Flouriot, Charly Jehanno, Yann le Page, Pascale le Goff, Benjamin Boutin, Denis Michel

 

Tools & resources

 

Derivation of endometrial gland organoids from term post-partum placenta
Mirna Marinic, Vincent J Lynch

 

 

Long-term in vivo imaging of Drosophila larvae
Parisa Kakanj, Sabine A. Eming, Linda Partridge, Maria Leptin

 

Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila
Leslie Ann Jaramillo Koyama, Andrés Aranda-Díaz, Yu-Han Su, Shruthi Balachandra, Judy Lisette Martin, William B. Ludington, Kerwyn Casey Huang, Lucy Erin O’Brien

 

Labeling proteins within Drosophila embryos by combining FRET reporters, position-specific genomic integration, and GAL4-reponsive expression
Tzyy-Chyn Deng, Chia-Jung Hsieh, Michael De Freitas, Maria Boulina, Nima Sharifai, Hasitha Samarajeewa, Tatsumi Yanaba, James D. Baker, Michael D. Kim, Susan Zusman, Kenneth H. Wan, Charles Yu, Susan E. Celniker, Akira Chiba

 

Targeted cell ablation in zebrafish using optogenetic transcriptional control
Karen Mruk, Paulina Ciepla, Patrick A. Piza, Mohammad A. Alnaqib, James K. Chen

 

High-performance chemical and light-inducible recombinases in mammalian cells and mice
Benjamin H. Weinberg, Jang Hwan Cho, Yash Agarwal, N. T. Hang Pham, Leidy D. Caraballo, Maciej Walkosz, Charina Ortega, Micaela Trexler, Nathan Tague, Billy Law, William K. J. Benman, Justin Letendre, Jacob Beal, Wilson W. Wong

 

Chromosome-level hybrid de novo genome assemblies as an attainable option for non-model organisms
Coline C. Jaworski, Carson W. Allan, Luciano M. Matzkin

 

Sequencing smart: De novo sequencing and assembly approaches for non-model mammals
Graham J Etherington, Darren Heavens, David Baker, Ashleigh Lister, Rose McNelly, Gonzalo Garcia, Bernardo Clavijo, Iain Macaulay, Wilfried Haerty, Federica Di Palma

 

A single CRISPR base editor to induce simultaneous C-to-T and A-to-G mutations
Rina C. Sakata, Soh Ishiguro, Hideto Mori, Mamoru Tanaka, Motoaki Seki, Nanami Masuyama, Keiji Nishida, Hiroshi Nishimasu, Akihiko Kondo, Osamu Nureki, Masaru Tomita, Hiroyuki Aburatani, Nozomu Yachie

 

Spatial and temporal control of CRISPR/Cas9-mediated gene editing delivered via a light-triggered liposome system
Yagiz Alp Aksoy, Wenjie Chen, Ewa M Goldys, Wei Deng

 

Compressed sensing for imaging transcriptomics
Brian Cleary, Evan Murray, Shahul Alam, Anubhav Sinha, Ehsan Habibi, Brooke Simonton, Jon Bezney, Jamie Marshall, Eric S. Lander, Fei Chen, Aviv Regev

 

A curated database reveals trends in single cell transcriptomics
Valentine Svensson, Eduardo da Veiga Beltrame

 

Research practice & education

What difference do retractions make? An estimate of the epistemic impact of retractions on recent meta-analyses
Daniele Fanelli, David Moher

 

From intent to implementation: Factors affecting public involvement in life science research
John. A. Burns, Kora Korzec, Emma R. Dorris

 

Gender bias in research teams and the underrepresentation of women in science
Roslyn Dakin, T. Brandt Ryder

 

The state of discovery-driven neuroscience research and experimental organism usage in the United States
Sarah M. Farris

 

Author-Reviewer Homophily in Peer Review
Dakota Murray, Kyle Siler, Vincent Larivière, Wei Mun Chan, Andrew M. Collings, Jennifer Raymond, Cassidy R. Sugimoto

 

 

Why not…

Genomic and phenotypic characterization of Burkholderia isolates from the potable water system of the International Space Station
Aubrie O’Rourke, Michael D Lee, William C Nierman, Chris L Dupont

 

 

 

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