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Displaying posts in the category: Research

In Development this week (Vol. 138, Issue 12)

Posted by , on 24 May 2011

Here are the highlights from the current issue of Development: How transcriptional silencing goes into reverse The Polycomb group (PcG) machinery silences terminal differentiation genes in stem cell lineages. Reversal ...

Development of electroreceptors: a “sixth sense”

Posted by , on 23 May 2011

Hi there! My name is Melinda, and I’m a postdoctoral researcher at Cambridge University in the UK in the lab of Dr. Clare Baker (http://www.pdn.cam.ac.uk/staff/baker/). I’ve just wrapped up my ...

A deep breath to kick off the BSCB-BSDB Spring Meeting 2011

Posted by , on 20 May 2011

BSCB-BSDB Spring meeting April 27 – 30, 2011 Canterbury University Since I very much enjoyed last year’s joint conference of the British Societies for Developmental Biology (BSDB) and Cell Biology ...

Imaging stem cells in the Drosophila ovary

Posted by , on 12 May 2011

To accompany our paper “Long-term live imaging provides new insight into stem cell regulation and germline-soma coordination in the Drosophila ovary” I have been asked by staff at the Node ...

When F-actin dynamics and Hippo signalling activity meet to regulate tissue growth.

Posted by , on 11 May 2011

Genetic screens in flies brought me by chance to have a look at one of the basic apparatus of the cell: the actin cytoskeleton. At that time, I remembered my ...

In Development this week (Vol. 138, Issue 11)

Posted by , on 10 May 2011

Here are the highlights from the current issue of Development: Dronc regulates Numb and neuroblast formation The ability of stem cells to maintain a balance between self-renewal and differentiation is ...

Zinc Finger Nucleases targeting genes in a frog near you!

Posted by , on 9 May 2011

Loss-of-function studies in Xenopus have been, until recently, limited to transient knockdowns by injection of morpholino antisense oligonucleotides.  In part because of X. laevis’ complex allotetraploid genome, the system lacked ...

The story behind the screen - flashbacks from the first RNAi screen in a whole vertebrate

Posted by , on 9 May 2011

The story of our recently released Development paper ‘FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools’ (http://dev.biologists.org/content/138/10/1893.full) involves hundreds of dozens ...

Healing an injured heart

Posted by , on 5 May 2011

Regenerative medicine and stem cell research go hand-in-hand when it comes to dreaming up future strategies for treating disease and injury in humans.  Today’s image is from a recent Development ...

March of Dimes Prize Announced

Posted by , on 4 May 2011

The March of Dimes Prize in Developmental Biology was jointly awarded this April to David Page, Director of the Whitehead Institute, and Patricia Ann Jacobs, professor of human genetics at ...

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