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Displaying posts in the category: Research

C. elegans Development, Cell Biology and Gene Expression and 2018 European Worm Meeting report

Posted by , on 9 July 2018

I recently attended the biennial Development, Cell Biology and Gene Expression C. elegans Meeting, this time in combination with the 2018 European Worm Meeting, in Barcelona. C. elegans meetings are ...

Stem cell makes its own niche: the story behind the paper

Posted by , on 7 July 2018

In our recent paper published in Nature, we unravel a new mechanism of an extracellular matrix protein secreted by muscle satellite (stem) cells, thereby playing the unusual role of acting ...

It’s alive! But what is it?

Posted by , on 5 July 2018

Iain Martyn & Tatiane Kanno share their experiences of the discovery of the human organizer   “It’s alive!”     Iain’s first impressions   “Hybrid human chicken embryos: HALF HUMAN – ...

How do pigment cells wander around?

Posted by , on 29 June 2018

The story behind melanocyte BACE2, posted by Yan Zhang and Richard White. You can read our recently published full article at Developmental Cell using this link.   Our story began six ...

Adult Neurogenesis 2018: Highlights -By Zubair Ahmed Nizamudeen

Posted by , on 29 June 2018

4WH Neurogenesis: What Where Why When and How? Neurogenesis is understood as the process by which neural stem cells (NSCs) produce new neurons. In the adult mammalian brain, this process ...

Towards understanding the quirks of human brain evolution

Posted by , on 28 June 2018

In early June, a group of 30 world-leading experts came together thanks to an invitation by the Company of Biologists to Wiston House (Sussex, UK) to discuss our current understanding ...

Blastoid: the backstory of the formation of blastocyst-like structure solely from stem cells.

Posted by , on 27 June 2018

In our recently published paper1, we showed that mouse stem cells self-organize into blastocyst-like structures, that we termed blastoids. Because blastoids can be generated in large numbers, can be finely ...

Visualizing data with R/ggplot2 - One more time

Posted by , on 26 June 2018

Experiments are rarely performed in isolation. Usually, several conditions are compared in parallel or sequential experiments. This experimental strategy also applies to time-dependent data, e.g. from timelapse imaging. So, naturally, ...

Unraveling tissue interactions coordinating neuromuscular morphogenesis: a journey through serendipity

Posted by , on 20 June 2018

An emerging trend in developmental biology focuses on the role of cell adhesion in modulating tissue morphogenesis. Spectacular advances have shed light on how modulation of adhesion between equivalent cells ...

Lighting Up the Central Dogma in Development

Posted by , on 19 June 2018

We recently published a manuscript in Cell that describes a method to image transcription factor concentration dynamics in real time, in living embryos, using a nanobody-based protein tag that we ...

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