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How mechanical signals orchestrate stem cell fate

Posted by , on 23 August 2016

Controlling differentiation using biophysical cues from development Embryonic stem cells have the potential to become any cell type in the adult organism, but coaxing them to a specific fate continues ...
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Forgotten classics: Tracing the heart

Posted by , on 17 August 2016

de la Cruz, M.V., Sánchez-Gómez, C. & Palomino, M.A. (1989) The primitive cardiac regions in the straight tube heart (Stage 9–) and their anatomical expression in the mature heart: an ...
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FaceBase: An online resource for craniofacial research

Posted by , on 16 August 2016

In 2009, FaceBase was launched in response to the need for more comprehensive analysis of craniofacial development: with so much craniofacial data being generated, there is a danger of relevant datasets ...
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A new role of an insect steroid hormone: The link between mating and germline stem cells

Posted by , on 11 August 2016

Tomotsune Ameku, Ryusuke Niwa’s lab, University of Tsukuba, Japan.   Steroid hormones have crucial roles in regulating a broad range of biological processes in most multicellular organisms. They are produced ...
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How many and which genes for multicellularity?

Posted by , on 9 August 2016

My research interest is the evolution of multicellularity. How did cells ‘learn’ to communicate with each other to build a structure that is more complex than its parts and shows ...
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MBL Embryology Course 2016

Posted by , on 1 August 2016

“My dear, here we must run as fast as we can, just to stay in place. And if you wish to go anywhere you must run twice as fast as ...
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How fish grew limbs and moved onto land

Posted by , on 25 July 2016

Fin to limb transition was a crucial evolutionary adaptation necessary for the vertebrate land invasion in the late Devonian around 400 MY ago. Without this key event, I would not ...
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From our sister journals - July 2016

Posted by , on 25 July 2016

Here we highlight some developmental biology related content from other journals published by The Company of Biologists.         Aging zebrafish an ideal model Mice have been the traditional model ...
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The dynamics of chromatin when life begins

Posted by , on 20 July 2016

Fertilization marks the start of life. This is followed by highly coordinated epigenetic reprogramming that allows protamine-histone exchange, zygotic genome activation, and the generation of a totipotent embryo. However, the ...
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In Development this week (Vol. 143, Issue 14)

Posted by , on 19 July 2016

Here are the highlights from the current issue of Development:   Gestational stress: at the heart of birth defects Congenital heart disease (CHD) is the most common form of human ...
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