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Journey to the East: from San Diego to Singapore

Posted by , on 18 July 2016

Axons in mature nervous systems regenerate poorly after injury, creating a major obstacle for recovery from neuronal injury. We know, however, that their regenerative capabilities are affected by both cell-extrinsic ...
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Research without boundaries - I remain an optimist

Posted by , on 16 July 2016

This week I attended a meeting with Paul Nurse, director of the The Francis Crick Institute, who spoke about the potential implications of the pending Brexit on scientific research at the ...
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3D retinas made from patient stem cells shed light on mechanisms of inherited blindness

Posted by , on 15 July 2016

Amelia Lane, David A. Parfitt, Conor M. Ramsden, Peter J. Coffey, Michael E. Cheetham   Parfitt et al. Cell Stem Cell 1–13 (2016)   Making eyes Methods to differentiate human ...
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Stem Cell & Higher-Order Chromatin Structure: Official meeting reporter wanted

Posted by , on 13 July 2016

Stem cells have the unique properties of both self renewal and differentiation into various lineages. In the last few years, chromatin architecture and noncoding RNAs are emerging as major players in both gene ...
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Revisiting the classics: coupling embryology with genomics to alter cell fate

Posted by , on 13 July 2016

Comment on “Reprogramming of avian neural crest axial identity and cell fate“, Science 352, 1570-1573, (2016). Marcos Simoes-Costa, Department of Molecular Biology and Genetics, Cornell University Marianne Bronner, Division of ...
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Deep into the developmental origins of neural tumours with Drosophila

Posted by , on 12 July 2016

Caroline Dillard and Cédric Maurange (Aix-Marseille University, CNRS, IBDM, Marseille)   Drosophila neural stem cells as a cancer model Transformation of a cell into a cancer cell is a complex ...
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Patterning in scale: a lesson from avian embryos

Posted by , on 7 July 2016

A fundamental property of all organisms is the remarkable consistency within the formation of the body plan during development. A handful of conserved molecular pathways are responsible for morphological patterning in ...
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June in preprints

Posted by , on 6 July 2016

In this new feature, we conduct a trawl for preprints to find the latest developmental biology and related research from the previous month. Scientists are increasingly using preprints as a way of ...
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In Development this week (Vol. 143, Issue 13)

Posted by , on 5 July 2016

Here are the highlights from the current issue of Development:   A pioneer role for PBX1 in neurogenesis The adult rodent subventricular zone (SVZ) is a neurogenic niche that provides ...
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Replicating spinal cord development with microfluidics

Posted by , on 5 July 2016

Unraveling Development Embryonic development is a complex and regulated spatiotemporal ensemble of signaling cues that control cell differentiation. Most of what we now know comes from experimenting directly on embryos. ...
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