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Displaying posts in the category: Research

Untangling developmentally programmed obesity: role of the serotonin system

Posted by , on 27 April 2016

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM): ‘5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in ...

Scratching the surface of a rainbow

Posted by , on 26 April 2016

  Why some vertebrates like salamanders and zebrafish are able to regenerate complex tissues while humans cannot is a question that has fascinated biologists for centuries. Understanding how and why ...

Gills, fins and the evolution of vertebrate paired appendages

Posted by , on 19 April 2016

The origin of paired fins is a major unresolved issue in vertebrate evolutionary biology, and has been a topic of debate among palaeontologists, comparative anatomists and developmental biologists for over ...

In Development this week (Vol. 143, Issue 8)

Posted by , on 19 April 2016

Here are the highlights from the current issue of Development:   The origins of lung macrophages revealed Tissue-resident macrophages are phagocytic cells that are essential for the response to injury ...

Light sheet microscopy 101: Get started with a short video protocol

Posted by , on 13 April 2016

Here you can find out more about our video protocol on using light sheet microscopy to image zebrafish eye development.   Light sheet fluorescence microscopy has quickly become a popular ...

High-pressure tubes

Posted by , on 6 April 2016

Notes on “Intracellular lumen formation in Drosophila proceeds via a novel subcellular compartment” by Linda S. Nikolova and Mark M. Metzstein. Development 2015 142: 3964-3973; doi: 10.1242/dev.127902 In this post, ...

Forgotten classics- Regulating the size of the mouse embryo

Posted by , on 6 April 2016

  Snow, M. H. L., Tam, P. P. L. (1979) Is compensatory growth a complicating factor in mouse teratology? Nature 279, 555-557 Lewis, N. E., Rossant, J. (1982) Mechanism of ...

In Development this week (Vol. 143, Issue 7)

Posted by , on 5 April 2016

Here are the highlights from the current issue of Development:   TUBB5 analysis yields insights into microcephaly Mutations affecting tubulin genes have been implicated in a range of human neurological ...

Obituary: Hans Meinhardt (1938-2016)

Posted by , on 29 March 2016

This obituary first appeared in Development.   Patrick Müller and Christiane Nüsslein-Volhard reflect on the life and career of their colleague Hans Meinhardt.   Hans Meinhardt, a pioneer in the field ...

Developing the auxin-inducible degradation (AID) system for versatile conditional protein depletion in C. elegans

Posted by , on 19 March 2016

By Liangyu Zhang and Abby F. Dernburg    The nematode Caenorhabidis elegans is among the most widely used and powerful model organisms for studying mechanisms underlying cellular and developmental processes. ...

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