the community site for and by developmental biologists

December in preprints

Posted by , on 6 January 2021

Welcome to our monthly trawl for developmental biology (and related) preprints. 


The preprints this month are hosted on bioRxiv and arXiv – use these links to get to the section you want.

Developmental biology

Patterning & signalling

Morphogenesis & mechanics

Genes & genomes

Stem cells, regeneration & disease modelling

Plant development

Evo-devo & evo
Cell biology
Modelling
Tools & resources
Research practice & education

 

 

Developmental biology

| Patterning & signalling

 

Vangl2 regulates the dynamics of Wnt cytonemes in vertebrates
Lucy Brunt, Gediminas Greicius, Benjamin D Evans, David M Virshup, Kyle CA Wedgwood, Steffen Scholpp

 

Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation
Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M Joaquina Delás, James Briscoe

 

Mouse cortex from Austin, et al.

 

Wnt/beta-catenin signalling is dispensable for adult neural stem cell homeostasis and activation
Sophie H. L. Austin, Lachlan Harris, Oana Paun, Piero Rigo, François Guillemot, Noelia Urbán

 

Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation
Raquel Atienzar-Aroca, José-Daniel Aroca-Aguilar, Susana Alexandre-Moreno, Jesús-José Ferre-Fernández, Juan-Manuel Bonet-Fernández, María-José Cabañero-Varela, Julio Escribano

`

SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2
Andrés Hernández-García, Sangbae Kim, Yumei Li, Bum Jun Kim, Hitisha P. Zaveri, Valerie K. Jordan, M. Cecilia Ljungberg, Rui Chen, Rainer B. Lanz, Daryl A. Scott

 

Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling
Sara E. Konopelski Snavely, Michael W. Susman, Ryan C. Kunz, Jia Tan, Srisathya Srinivasan, Michael D. Cohen, Kyoko Okada, Helen Lamb, Shannon S. Choi, Edith P. Karuna, Michael K. Scales, Steven P. Gygi, Michael E. Greenberg, Hsin-Yi Henry Ho

 

Planarians in Pascual-Carreras, et al.

 

Genomic analyses reveal FoxG as an upstream regulator of wnt1 required for posterior identity specification in planarians
E. Pascual-Carreras, M. Marín-Barba, S. Castillo-Lara, P. Coronel-Córdoba, M.S. Magri, G.N. Wheeler, J.F. Abril, J.L. Gomez-Skarmeta, E. Saló, T. Adell

 

Fly egg chambers from Wang, et al.

 

Extracellular spreading of Wingless is required for Drosophila oogenesis
Xiaoxi Wang, Kimberly S. LaFever, Indrayani Waghmare, Andrea Page-McCaw

 

Canonical Wnt signaling exerts bidirectional control on choroid plexus epithelial development
Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M. Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Nataša Jovanov Milošević, Orly Reiner, Shubha Tole

 

The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
Sheng Zhang, Yan Wang, Xiaoqing Zhu, Lanying Song, Xinhua Zhan, Edric Ma, Jennifer McDonough, Hui Fu, Franca Cambi, Judith Grinspan, Fuzheng Guo

 

Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube
Shai Ofek, Sophie Wiszniak, Sarah Kagan, Markus Tondl, Quenten Schwarz, Chaya Kalcheim

 

Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis
David Mellis, Katherine A Staines, Silvia Peluso, Ioanna Ch. Georgiou, Natalie Dora, Malgorzata Kubiak, Michela Grillo, Colin Farquharson, Elaine Kinsella, Anna Thornburn, Stuart H Ralston, Donald M Salter, Natalia A Riobo-Del Galdo, Robert E Hill, Mark Ditzel

 

Non-cell autonomous inhibition of the Shh pathway due to impaired cholesterol biosynthesis requires Ptch1/2
Carian Jägers, Henk Roelink

 

Dissecting signalling hierarchies in the patterning of the mouse primitive streak using micro-patterned EpiLC colonies
Jean-Louis Plouhinec, Mathieu Vieira, Gaël Simon, Jérôme Collignon, Benoit Sorre

 

A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord
V Biga, J Hawley, X Soto, E Johns, D Han, H Bennett, AD Adamson, J Kursawe, P Glendinning, C.S Manning, N Papalopulu

 

longfin causes cis-ectopic expression of the kcnh2a ether-a-go-go K+ channel to autonomously prolong fin outgrowth
Scott Stewart, Heather K. Le Bleu, Gabriel A. Yette, Astra L. Henner, Amy E. Robbins, Joshua A. Braunstein, Kryn Stankunas

 

The Broad Role of Nkx3.2 in the Development of the Zebrafish Axial Skeleton
Laura Waldmann, Jake Leyhr, Hanqing Zhang, Caroline Öhman-Mägi, Amin Allalou, Tatjana Haitina

 

osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2
Bridgette E. Drummond, Brooke E. Chambers, Hannah M. Wesselman, Marisa N. Ulrich, Gary F. Gerlach, Paul T. Kroeger, Ignaty Leshchiner, Wolfram Goessling, Rebecca A. Wingert

 

Human embryonic stem cell colonies in Phan-Everson, et al.

 

Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport
Tien Minh-Thuy Phan-Everson, Fred Etoc, Ali H Brivanlou, Eric D Siggia

 

Variability of an early developmental cell population underlies stochastic laterality defects
Roberto Moreno-Ayala, Pedro Olivares-Chauvet, Ronny Schäfer, Jan Philipp Junker

 

Valproic acid stimulates myogenesis in pluripotent stem cell–derived mesodermal progenitors in a Notch-dependent manner
Natacha Breuls, Nefele Giarratana, Laura Yedigaryan, Paolo Carai, Stephane Heymans, Adrian Ranga, Christophe M. Deroose, Maurilio Sampaolesi

 

Mouse ribs from Kweon, et al.

 

Naa12 rescues embryonic lethality in Naa10-Deficient Mice in the amino-terminal acetylation pathway
Hyae Yon Kweon, Mi-Ni Lee, Max Dörfel, Seungwoon Seo, Leah Gottlieb, Thomas Papazyan, Nina McTiernan, Rasmus Ree, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J. Conway, TaeSoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Gholson J. Lyon, Goo Taeg Oh

 

SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells
Romina J. Bevacqua, Jonathan Y. Lam, Heshan Peiris, Robert L. Whitener, Seokho Kim, Xueying Gu, Mollie S.H. Friedlander, Seung K. Kim

 

Lactate Accelerates Mouse ES Cell Differentiation Towards the XEN Lineage
Mohamed I. Gatie, Tyler T. Cooper, Gilles A. Lajoie, Gregory M. Kelly

 

ICM cells can be partitioned robustly through transient synchronization using secreted FGF4
Xiaochan Xu, Ala Trusina, Kim Sneppen

 

Zebrafish vasculature from Zhou, et al.

 

Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks
Qi Zhou, Tijana Perovic, Ines Fechner, Lowell T. Edgar, Peter R. Hoskins, Holger Gerhardt, Timm Krüger, Miguel O. Bernabeu

 

Interneuron origins in the embryonic porcine medial ganglionic eminence
Mariana L. Casalia, Tina Li, Harrison Ramsay, Pablo J. Ross, Mercedes F. Paredes, Scott C. Baraban

 

MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis
Patrick A. Carroll, Pei Feng Cheng, Brian W Freie, Sivakanthan Kasinathan, Haiwei Gu, Theresa Hedrich, James A. Dowdle, Vivek Venkataramani, Vijay Ramani, Daniel Raftery, Jay Shendure, Donald E. Ayer, Charles H. Muller, Robert N. Eisenman

 

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord
Kalaimakan Hervé Arulkandarajah, Guillaume Osterstock, Agathe Lafont, Hervé Le Corronc, Nathalie Escalas, Silvia Corsini, Barbara Le Bras, Juliette Boeri, Antonny Czarnecki, Christine Mouffle, Erika Bullier, Elim Hong, Cathy Soula, Pascal Legendre, Jean-Marie Mangin

 

Zfp36l1 and Zfp36l2 balances proliferation and differentiation in the developing retina
Fuguo Wu, Tadeusz Kaczynski, Louise S. Matheson, Tao Liu, Jie Wang, Martin Turner, Xiuqian Mu

 

DDI2 protease activity controls embryonic development and inflammation via TCF11/NRF1
Monika Siva, Stefanie Haberecht-Müller, Michaela Prochazkova, Jan Prochazka, Frantisek Sedlak, Kallayanee Chawengsaksophak, Petr Kasparek, Radislav Sedlacek, Jan Konvalinka, Elke Krüger, Klara Grantz Saskova

 

Muscle Van Gogh-like 2 shapes the neuromuscular synapse by regulating MuSK signaling activity
Myriam Boëx, Julien Messéant, Steve Cottin, Marius Halliez, Stéphanie Bauché, Céline Buon, Nathalie Sans, Mireille Montcouquiol, Jordi Molgó, Muriel Amar, Arnaud Ferry, Mégane Lemaitre, Andrée Rouche, Dominique Langui, Asha Baskaran, Bertrand Fontaine, Laure Strochlic

 

Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation in rabbits
Geneviève Jolivet, Nathalie Daniel-Carlier, Erwana Harscoët, Eloïse Airaud, Aurélie Dewaele, Cloé Pierson, Frank Giton, Laurent Boulanger, Nathalie Daniel, Béatrice Mandon-Pépin, Maëlle Pannetier, Eric Pailhoux

 

Mechano-chemical feedback leads to competition for BMP signalling during pattern formation
Daniel J. Toddie-Moore, Martti P. Montanari, Ngan Vi Tran, Evgeniy M. Brik, Hanna Antson, Isaac Salazar-Ciudad, Osamu Shimmi

 

Lineage-specific control of convergent differentiation by a Forkhead repressor
Karolina Mizeracka, Julia M. Rogers, Jonathan D. Rumley, Shai Shaham, Martha L. Bulyk, John I. Murray, Maxwell G. Heiman

 

DAF-16/FoxO and DAF-12/VDR control cellular plasticity both cell-autonomously and via interorgan signaling
Ulkar Aghayeva, Abhishek Bhattacharya, Surojit Sural, Eliza Jaeger, Matthew Churgin, Christopher Fang-Yen, Oliver Hobert

 

Sustained expression of unc-4/Hox and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans
Mizuki Kurashina, Jane Wang, Kathy Kyungeun Lee, Arpun Johal, Kota Mizumoto

 

Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in C. elegans
Mor Levi-Ferber, Rewayd Shalash, Adrien Le Thomas, Yehuda Salzberg, Maor Shurgi, Avi Ashkenazi, Sivan Henis-Korenblit

 

Functional analysis of caspase cleavable proteoforms from the Drosophila GSK-3 gene shaggy
Dagmara Korona, Daniel Nightingale, Bertrand Fabre, Michael Nelson, Bettina Fischer, Glynnis Johnson, Simon Hubbard, Kathryn Lilley, Steven Russell

 

Fly wing discs from Zhao, et al.

 

Bab2 activates JNK signaling to reprogram Drosophila wing disc development
Yunpo Zhao, Jianli Duan, Alexis Dziedziech, Sabrina Büttner, Ylva Engström

 

Autonomous termination of proliferation in the Drosophila wing disc is TORC1 dependent
Katrin Strassburger, Marilena Lutz, Sandra Müller, Aurelio A. Teleman

 

JNK signaling in pioneer neurons directs the architectural organization of the CNS and coordinates the motor activity of the Drosophila embryo
Katerina Karkali, Timothy E. Saunders, Samuel W. Vernon, Richard A. Baines, George Panayotou, Enrique Martín-Blanco

 

Ecdysone coordinates plastic growth with robust pattern in the developing wing
André Nogueira Alves, Marisa Mateus Oliveira, Takashi Koyama, Alexander Shingleton, Christen Mirth

 

Fly embryos from Tiwari, et al.

 

Scaling of Internal Organs during Drosophila Embryonic Development
P. Tiwari, H. Rengarajan, T. E. Saunders

 

The tolerance to hypoxia is defined by a time-sensitive response of the gene regulatory network in sea urchin embryos
Majed Layous, Lama Khalaily, Tsvia Gildor, Smadar Ben-Tabou de-Leon

 

Cellular and Developmental Basis of Avian Structural Coloration
Vinodkumar Saranathan, Cédric Finet

 

 

 

| Morphogenesis & mechanics

 

Wnt/β-Catenin Signaling Controls Spatio-Temporal Elasticity Patterns in Extracellular Matrix during Hydra Morphogenesis
Mariam Veschgini, Hendrik O Petersen, Fernanda F Rossetti, Wasim Abuillan, Stefan Kaufmann, Ryo Suzuki, Manfred Burghammer, Suat Özbek, Thomas W Holstein, Motomu Tanaka

 

Wnt3 expression as a readout of tissue stretching during Hydra regeneration
Jaroslav Ferenc, Panagiotis Papasaikas, Jacqueline Ferralli, Yukio Nakamura, Sebastien Smallwood, Charisios D. Tsiairis

 

Zebrabow from Peloggia, et al.

 

Adaptive cell invasion maintains organ homeostasis
Julia Peloggia, Daniela Münch, Paloma Meneses-Giles, Andrés Romero-Carvajal, Melainia McClain, Y. Albert Pan, Tatjana Piotrowski

 

F-actin Re-organization Mediates Hierarchical Morphogenesis of Swallowtail Butterfly Wing Scale Nanostructures
Kwi Shan Seah, Vinodkumar Saranathan

 

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
Emma Carley, Rachel K. Stewart, Abigail Zieman, Iman Jalilian, Diane. E. King, Amanda Zubek, Samantha Lin, Valerie Horsley, Megan C. King

 

Maternal vgll4a promotes blastoderm cohesion enabling yap1-mediated mechano-transduction during zebrafish epiboly
Carlos Camacho-Macorra, Noemí Tabanera, Paola Bovolenta, Marcos J Cardozo

 

Modelling actomyosin in Bhide, et al.

 

Mechanical competition alters the cellular interpretation of an endogenous genetic programme
Sourabh Bhide, Denisa Gombalova, Gregor Mönke, Johannes Stegmaier, Valentyna Zinchenko, Anna Kreshuk, Julio M Belmonte, Maria Leptin

 

Deletion of INPP5E in the murine retina impairs axoneme formation and prevents photoreceptor disc morphogenesis
Ali S. Sharif, Cecilia D. Gerstner, Martha A. Cady, Vadim Y. Arshavsky, Christina Mitchell, Guoxin Ying, Jeanne M. Frederick, Wolfgang Baehr

 

Arrested coalescence of multicellular aggregates
David Oriola, Miquel Marin-Riera, Germaine Aalderink, Kerim Anlas, Nicola Gritti, James Sharpe, Vikas Trivedi

 

Axial Elongation of Caudalized Human Organoids Mimics Neural Tube Development
ARG Libby, DA Joy, NH Elder, EA Bulger, MZ Krakora, EA Gaylord, F Mendoza-Camacho, JC Butts, TC McDevitt

 

Somite surface tension buffers imprecise segment lengths to ensure left-right symmetry
Sundar R. Naganathan, Marko Popović, Andrew C. Oates

 

Fly egg chamber from Lu, et al

 

Short stop is a gatekeeper at the ring canals of Drosophila ovary
Wen Lu, Margot Lakonishok, Vladimir I. Gelfand

 

The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
Alessandra Gentile, Anabela Bensimon-Brito, Rashmi Priya, Hans-Martin Maischein, Janett Piesker, Stefan Günther, Felix Gunawan, Didier Y.R. Stainier

 

Microtubule asters in de-Carvalho, et al.

 

Aster repulsion drives local ordering in an active system
Jorge de-Carvalho, Sham Tlili, Lars Hufnagel, Timothy E. Saunders, Ivo A. Telley

 

Physics of blastocoel formation by hydro-osmotic lumen coarsening
Mathieu Le Verge–Serandour, Hervé Turlier

 

Vimentin provides target search efficiency and mechanical resilience for dendritic cell migration
Luiza Da Cunha Stankevicins, M. Reza Shaebani, Doriane Vesperini, Marta Urbanska, Daniel A. D. Flormann, Emmanuel Terriac, Annica K. B. Gad, Fang Cheng, John E. Eriksson, Franziska Lautenschläger

 

BAP1/ASXL complex modulation regulates Epithelial-Mesenchymal Transition during trophoblast differentiation and invasion
Vicente Perez-Garcia, Pablo Lopez-Jimenez, Graham J Burton, Ashley Moffett, Margherita Y. Turco, Myriam Hemberger

 

C. elegans intestine from Remmelzwaal, et al.

 

BBLN-1 is essential for intermediate filament organization and apical membrane morphology
Sanne Remmelzwaal, Florian Geisler, Riccardo Stucchi, Suzanne van der Horst, Milena Pasolli, Jason R. Kroll, Olga D. Jarosinska, Anna Akhmanova, Christine A. Richardson, Maarten Altelaar, Rudolf E. Leube, João J. Ramalho, Mike Boxem

 

Rapid assembly of a polar network architecture by formins downstream of RhoA pulses drives efficient cortical actomyosin contractility
Vlad Costache, Serena Prigent Garcia, Camille N. Plancke, Jing Li, Simon Begnaud, Shashi Kumar Suman, Taeyoon Kim, François B. Robin

 

C. elegans embryos

 

A Genetic Screen for Temperature-sensitive Morphogenesis-defective Caenorhabditis elegans Mutants
Molly Christine Jud, Josh Lowry, Thalia Padilla, Erin Clifford, Yuqi Yang, Francesca Fennell, Alexander Miller, Danielle Hamill, Austin Harvey, Martha Avila-Zavala, Hong Shao, Nhah NguyenTran, Zhirong Bao, Bruce Bowerman

 

The Control of Lung Branching Morphogenesis
Dagmar Iber

 

 

| Genes & genomes

 

An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution
Aubrey G.A. Howard IV, Phillip A. Baker, Rodrigo Ibarra-García-Padilla, Joshua A. Moore, Lucia J. Rivas, James J. Tallman, Eileen W. Singleton, Jessa L. Westheimer, Julia A. Corteguera, Rosa A. Uribe

 

Single cell transcriptomics of the developing zebrafish lens and identification of putative controllers of lens development
Dylan Farnsworth, Mason Posner, Adam Miller

 

Zebrafish neural crest in Lencer, et al.

 

Single cell RNA analysis of trunk neural crest cells in zebrafish identifies pre-migratory populations expressing markers of differentiated derivatives
Ezra Lencer, Rytis Prekeris, Kristin Bruk Artinger

 

Diversity of developing peripheral glia revealed by single cell RNA sequencing
OE Tasdemir-Yilmaz, NR Druckenbrod, OO Olukoya, AR Yung, I Bastille, MF Pazyra-Murphy, A Sitko, EB Hale, S Vigneau, AA Gimelbrant, P Kharchenko, LV Goodrich, RA Segal

 

Resolving the transcriptional transitions associated with oligodendrocyte generation from adult neural stem cells by single cell sequencing
Kasum Azim, Filippo Calzolari, Martina Cantone, Rainer Akkermann, Julio Vera, Hans-Peter Hartung, Onur Basak, Arthur Morgan Butt, Patrick Küry

 

Single-Cell Atlas of Early Human Brain Development Highlights Heterogeneity of Human Neuroepithelial Cells and Early Radial Glia
Ugomma C. Eze, Aparna Bhaduri, Maximilian Haeussler, Tomasz J. Nowakowski, Arnold R. Kriegstein

 

Dissecting human skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses
Jian He, Jing Yan, Jianfang Wang, Liangyu Zhao, Qian Xin, Yang Zeng, Yuxi Sun, Han Zhang, Zhijie Bai, Zongcheng Li, Yanli Ni, Yandong Gong, Yunqiao Li, Han He, Zhilei Bian, Yu Lan, Chunyu Ma, Lihong Bian, Heng Zhu, Bing Liu, Rui Yue

 

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm
Hiroko Nomaru, Yang Liu, Christopher De Bono, Dario Righelli, Andrea Cirino, Wei Wang, Silvia E. Racedo, Anelisa G. Dantas, Chenleng Cai, Claudia Angelini, Lionel Christiaen, Robert G. Kelly, Antonio Baldini, Deyou Zheng, Bernice Morrow

 

Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development
Xiangmei Zhang, Igor Mandric, Kevin H. Nguyen, Thao T. T. Nguyen, Matteo Pellegrini, James C. R. Grove, Steven Barnes, Xian-Jie Yang

 

Distinct expression of select and transcriptome-wide isolated 3’UTRs suggests critical roles in development and transition states
Shaoyi Ji, Ze Yang, Leonardi Gozali, Thomas Kenney, Arif Kocabas, Carolyn Jinsook Park, Mary Hynes

 

Mouse pancreas from Campbell, et al.

 

H3K4 trimethylation is required for postnatal pancreatic endocrine cell functional maturation
Stephanie A. Campbell, Jocelyn Bégin, Cassandra L. McDonald, Ben Vanderkruk, Tabea L. Stephan, Brad G. Hoffman

 

Epigenetic control of coordinated hematopoietic and cardiovascular development by Rnf2 in zebrafish
XX Peng, G Feng, YH Sun

 

Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome
Eishi Aizawa, Corinne Kaufmann, Sarah Sting, Remo Freimann, Anton Wutz

 

SPEN is Required for Xist Upregulation during Initiation of X Chromosome Inactivation
Teresa Robert-Finestra, Beatrice F. Tan, Hegias Mira-Bontenbal, Erika Timmers, Cristina Gontan-Pardo, Sarra Merzouk, Benedetto Daniele Giaimo, François Dossin, Wilfred F. J. van IJcken, John W. M. Martens, Tilman Borggrefe, Edith Heard, Joost Gribnau

 

Oct1 recruits the histone lysine demethylase Utx to canalize lineage specification
Jelena Perovanovic, Zuolian Shen, Yifan Wu, Dean Tantin

 

Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation
Alessandro Angerilli, Janet Tait, Julian Berges, Irina Shcherbakova, Tamas Schauer, Pawel Smialowski, Ohnmar Hsam, Edith Mentele, Dario Nicetto, Ralph A.W. Rupp

 

Mouse retina from Schick. et al.

 

Early cis-regulatory events in the formation of retinal horizontal cells
Estie Schick, Kevin C. Gonzalez, Pooja Dutta, Kazi Hossain, Miruna G. Ghinia Tegla, Mark M. Emerson

 

The comprehensive roadmaps of reprogramming and transformation unveiled antagonistic roles for bHLH transcription factors in the control of cellular plasticity
A. Huyghe, G. Furlan, J. Schroeder, J. Stüder, F. Mugnier, L. De Matteo, J. Wang, Y. Yu, N. Rama, B. Gibert, P. Wajda, I. Goddard, N. Gadot, M. Brevet, M. Siouda, P. Mulligan, R. Dante, P. Liu, H. Gronemeyer, M. Mendoza-Parra, J. Polo, F. Lavial

 

Mouse brains from Doyle, et al.

 

Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity
Daniel Z. Doyle, Mandy M. Lam, Adel Qalieh, Yaman Qalieh, Alice Sorel, Owen H. Funk, Kenneth Y. Kwan

 

Coordinated Changes in Gene Expression Kinetics Underlie both Mouse and Human Erythroid Maturation
Melania Barile, Ivan Imaz-Rosshandler, Isabella Inzani, Shila Ghazanfar, Jennifer Nichols, John C. Marioni, Carolina Guibentif, Berthold Göttgens

 

The transcription factor FoxO1 is required for the establishment of the human definitive endoderm
Joshua Nord, Daniel Schill, Kirthi Pulakanti, Sridhar Rao, Lisa Ann Cirillo

 

Mouse embryos from Legault, et al.

 

Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain
LM Legault, K Doiron, M Breton-Larrivée, A Langford-Avelar, A Lemieux, M Caron, LA Jerome-Majewska, D Sinnett, S McGraw

 

AF10 (MLLT10) prevents somatic cell reprogramming through regulation of H3K79 methylation
Deniz Uğurlu-Çimen, Deniz Odluyurt, Kenan Sevinç, Nazlı Ezgi Özkan-Küçük, Burcu Özçimen, Deniz Demirtaş, Martin Philpott, Udo Oppermann, Nurhan Özlü, Tamer T. Önder

 

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation
Jinyue Liao, Hoi Ching Suen, Alfred Chun Shui Luk, Tin-Lap Lee

 

Eve in the fly embryo, from Barinov, et al.

 

Transcription-dependent spatial organization of a gene locus
Lev Barinov, Sergey Ryabichko, William Bialek, Thomas Gregor

 

The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
Binta Jalloh, J. Christopher Rounds, Brianna E. Brown, Isaac J. Kremsky, Ayan Banerjee, Derrick J. Morton, Rick S. Bienkowski, Milo B. Fasken, Anita H. Corbett, Kenneth H. Moberg

 

 

| Stem cells, regeneration & disease modelling

 

Low levels of Grainy head isoforms regulate Drosophila midgut intestinal stem cell differentiation
Nicole Dominado, Franca Casagranda, Nicole A. Siddall, Helen E. Abud, Gary R. Hime

 

Drosophila neural stem cells show a unique dynamic pattern of gene expression that is influenced by environmental factors
Alix Goupil, Carole Pennetier, Anthony Simon, Patricia Skorski, Allison Bardin, Renata Basto

 

Non-homologous end joining factors XLF, PAXX and DNA-PKcs support neural stem and progenitor cells development
Raquel Gago-Fuentes, Valentyn Oksenych

 

Neural stem cell interkinetic nuclear migration is controlled by a phosphatidylinositol transfer protein/non-canonical planar cell polarity signaling axis
Zhigang Xie, Vytas A. Bankaitis

 

Mouse cortices from Fabra-Beser, et al.

 

Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation
Jaime Fabra-Beser, Jessica Alves Medeiros de Araujo, Diego Marques-Coelho, Loyal A. Goff, Ulrich Müller, Cristina Gil-Sanz

 

Coordinated regulation of ribosomes and proteasomes by PRMT1 in the maintenance of neural stemness of cancer cells and neural stem cells
Lu Chen, Min Zhang, Lei Fang, Xiaoli Yang, Liyang Xu, Lihua Shi, Ning Cao, Ying Cao

 

Dot1L interaction partner AF10 safeguards cell identity during the acquisition of pluripotency
Coral K. Wille, Edwin N. Neumann, Aniruddha J. Deshpande, Rupa Sridharan

 

Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells
Dhruv Raina, Fiorella Fabris, Luis G. Morelli, Christian Schröter

 

Capturing Human Trophoblast Development with Naïve Pluripotent Stem Cells In Vitro
Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi, Nobuhiro Morone, Ikuhiro Okamoto, Tomonori Nakamura, Yoji Kojima, Chizuru Iwatani, Hideaki Tsuchiya, Belinda Kaswandy, Eiji Kondoh, Mitinori Saitou, Takuya Yamamoto, Masaki Mandai, Yasuhiro Takashima

 

Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors
Ying Li, Bhagirath Chaurasia, Vincent Kaddai, Joseph L. Wilkerson, J. Alan Maschek, James Cox, Peng Wei, Claire Bensard, Peter J Meikle, Hans Clevers, James A Shayman, Yoshio Hirabayashi, William L. Holland, Jared Rutter, Scott A. Summers

 

KLF17 promotes human naïve pluripotency but is not required for its establishment
Rebecca A. Lea, Afshan McCarthy, Stefan Boeing, Kathy K. Niakan

 

CTCF is a Barrier for Totipotent-like Reprogramming
Teresa Olbrich, Maria Vega-Sendino, Desiree Tillo, Wei Wu, Nicholas Zolnerowich, Andy D. Tran, Catherine N. Domingo, Mariajose Franco, Marta Markiewicz-Potoczny, Gianluca Pegoraro, Peter C. FitzGerald, Michael J. Kruhlak, Eros Lazzerini-Denchi, Elphege P. Nora, Andre Nussenzweig, Sergio Ruiz

 

Mouse embryonic stem cells switch migratory behaviour during early differentiation
Irene M. Aspalter, Wolfram Pönisch, Kevin J. Chalut, Ewa K. Paluch

 

De novo DNA methylation suppresses aberrant fate determination during pluripotency transition
Masaki Kinoshita, Meng Amy Li, Michael Barber, William Mansfield, Sabine Dietmann, Austin Smith

 

INO80 promotes H2A.Z occupancy to regulate cell fate transition in pluripotent stem cells
Hongyao Yu, Jiajia Wang, Brad Lackford, Brian Bennett, Jian-liang Li, Guang Hu

 

Robust integrated intracellular organization of the human iPS cell: where, how much, and how variable?
Matheus P. Viana, Jianxu Chen, Theo A. Knijnenburg, Ritvik Vasan, Calysta Yan, Joy E. Arakaki, Matte Bailey, Ben Berry, Antoine Borensztejn, Jackson M. Brown, Sara Carlson, Julie A. Cass, Basudev Chaudhuri, Kimberly R. Cordes Metzler, Mackenzie E. Coston, Zach J. Crabtree, Steve Davidson, Colette M. DeLizo, Shailja Dhaka, Stephanie Q. Dinh, Thao P. Do, Justin Domingus, Rory M. Donovan-Maiye, Tyler J. Foster, Christopher L. Frick, Griffin Fujioka, Margaret A. Fuqua, Jamie L. Gehring, Kaytlyn A. Gerbin, Tanya Grancharova, Benjamin W. Gregor, Lisa Harrylock, Amanda Haupt, Melissa C. Hendershott, Caroline Hookway, Alan R. Horwitz, Chris Hughes, Eric J. Isaac, Gregory R. Johnson, Brian Kim, Andrew N. Leonard, Winnie Leung, Jordan J. Lucas, Susan A. Ludmann, Blair M. Lyons, Haseeb Malik, Ryan McGregor, Gabe E. Medrash, Sean L. Meharry, Kevin Mitcham, Irina A. Mueller, Timothy L. Murphy-Stevens, Aditya Nath, Angelique M. Nelson, Luana Paleologu, T. Alexander Popiel, Megan M. Riel-Mehan, Brock Roberts, Lisa M. Schaefbauer, Magdalena Schwarzl, Jamie Sherman, Sylvain Slaton, M. Filip Sluzewski, Jacqueline E. Smith, Youngmee Sul, Madison J. Swain-Bowden, W. Joyce Tang, Derek J. Thirstrup, Daniel T. Toloudis, Andrew P. Tucker, Veronica Valencia, Winfried Wiegraebe, Thushara Wijeratna, Ruian Yang, Rebecca J. Zaunbrecher, Allen Institute for Cell Science, Graham T. Johnson, Ruwanthi N. Gunawardane, Nathalie Gaudreault, Julie A. Theriot, Susanne M. Rafelski

 

SUMO maintains the chromatin environment of human induced pluripotent stem cells
Barbara Mojsa, Michael H. Tatham, Lindsay Davidson, Magda Liczmanska, Jane E. Wright, Nicola Wiechens, Marek Gierlinski, Tom Owen-Hughes, Ronald T. Hay

 

Dynamic erasure of X chromosome upregulation during iPSC reprogramming and in the inner cell mass
D Chandel, C H Naik, S Gayen

 

Sestrins regulate age-induced deterioration of muscle stem cell homeostasis
Benjamin A. Yang, Jesus Castor-Macias, Paula Fraczek, Lemuel A. Brown, Myungjin Kim, Susan V. Brooks, Jun Hee Lee, Carlos A. Aguilar

 

Characterization of human embryonic stem cells in animal component-free medium
Masakazu Machida, Rie Abutani, Hiroshi Miyajima, Tetsuji Sasaki, Yoshiko Abe, Hidenori Akutsu, Akihiro Umezawa

 

Direct differentiation of Dental Pulp Pluripotent-like Stem Cells differentiation into Hepatocyte-like Cells
Carlos Gil-Recio, Sheyla Montori, Cámara Vallejo, Saddam Al Demour, E. Ferrés-Padró, Miguel Barajas, Carles Martin, Ashraf Al Madhoun, Maher Atari

 

Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration
Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-Ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey L. Goldberg, Clifford J. Woolf, Michael V. Sofroniew, Larry I. Benowitz, Daniel H. Geschwind

 

Dynamics and variability of neuronal subtype responses during growth, degrowth, and regeneration
Jamie A. Havrilak, Layla Al-Shaer, Noor Baban, Nesli Akinci, Michael J. Layden

 

Decellularization enables functional analysis of ECM remodeling in planarian regeneration
Ekasit Sonpho, Frederick G. Mann Jr., Michaella Levy, Eric J. Ross, Carlos Guerrero-Hernández, Laurence Florens, Anita Saraf, Viraj Doddihal, Puey Ounjai, Alejandro Sánchez Alvarado

 

Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona
William R. Jeffery, Spela Goricki

 

Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration
Monica R. Langley, Chan-Il Choi, Thais R. Peclat, Yong Guo, Whitney Simon, Hyesook Yoon, Laurel Kleppe, Claudia F. Lucchinetti, Claudia C.S. Chini, Eduardo N. Chini, Isobel A. Scarisbrick

 

Robo2 drives target selective peripheral nerve regeneration in response to glia derived signals
Patricia L. Murphy, Jesse Isaacman-Beck, Michael Granato

 

Zebrafish notochords from Lopez-Cuevas, et al.

 

Transformed notochordal cells trigger chronic wounds destabilizing the vertebral column and bone homeostasis
Paco Lopez-Cuevas, Luke Deane, Yushi Yang, Chrissy L Hammond, Erika Kague

 

16p12.1 deletion orthologs are expressed in motile neural crest cells and are important for regulating craniofacial development in Xenopus laevis
Micaela Lasser, Jessica Bolduc, Luke Murphy, Caroline O’Brien, Sangmook Lee, Santhosh Girirajan, Laura Anne Lowery

 

Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with Ebstein’s anomaly
Wei Feng, Hannah Schriever, Shan Jiang, Abha Bais, Dennis Kostka, Guang Li

 

A MYT1L Syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
Jiayang Chen, Mary E. Lambo, Xia Ge, Joshua T. Dearborn, Yating Liu, Katherine B. McCullough, Raylynn G. Swift, Dora R. Tabachnick, Lucy Tian, Kevin Noguchi, Joel R. Garbow, Harrison W. Gabel, Keith B. Hengen, Susan E. Maloney, Joseph D. Dougherty

 

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
Courtney Tindle, MacKenzie Fuller, Ayden Fonseca, Sahar Taheri, Stella-Rita Ibeawuchi, Nathan Beutler, Amanraj Claire, Vanessa Castillo, Moises Hernandez, Hana Russo, Jason Duran, Laura E. Crotty Alexander, Ann Tipps, Grace Lin, Patricia A. Thistlethwaite, Ranajoy Chattopadhyay, Thomas F. Rogers, Debashis Sahoo, Pradipta Ghosh, Soumita Das

 

Neural stem cells restore motor and cognitive function in a macaque model of Parkinson′s disease
Florence Wianny, Kwamivi Dzahini, Karim Fifel, Charles R.E. Wilson, Agnieszka Bernat, Virginie Dolmazon, Pierre Misery, Camille Lamy, Howard M. Cooper, Emmanuel Procyk, Henry Kennedy, Pierre Savatier, Colette Dehay, Julien Vezoli

 

Differences in neuronal numbers, morphology and developmental apoptosis in mice nigra provide experimental evidence of ontogenic origin of vulnerability to Parkinson’s disease
D J Vidyadhara, Haorei Yarreiphang, Trichur R Raju, Phalguni Anand Alladi

 

A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome
Francisco Bustos, Carmen Espejo-Serrano, Anna Segarra-Fas, Alison J. Eaton, Kristin D. Kernohan, Meredith J. Wilson, Lisa G. Riley, Greg M. Findlay

 

Mouse synapses from  Prieto, et al.

 

Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense Fmr1 mutant mouse model of Fragile X syndrome
Marta Prieto, Alessandra Folci, Gwénola Poupon, Sara Schiavi, Valeria Buzzelli, Marie Pronot, Urielle François, Paula Pousinha, Norma Lattuada, Sophie Abelanet, Sara Castagnola, Magda Chafai, Anouar Khayachi, Carole Gwizdek, Frédéric Brau, Emmanuel Deval, Maura Francolini, Barbara Bardoni, Yann Humeau, Viviana Trezza, Stéphane Martin

 

Grb10a knockdown in Danio rerio during early life alters growth and cardiometabolic function associated with a remodelled transcriptome
Bridget L Evans, Terence Garner, Chiara De Leonibus, Oliver H Wearing, Holly A Shiels, Adam F L Hurlstone, Peter E Clayton, Adam Stevens

 

Ste20-like kinase is critical for inhibitory synapse maintenance and its deficiency confers a developmental dendritopathy
Susanne Schoch, Anne Quatraccioni, Barbara K. Robens, Robert Maresch, Karen M.J. van Loo, Tony Kelly, Thoralf Opitz, Valeri Borger, Dirk Dietrich, Julika Pitsch, Heinz Beck, Albert J. Becker

 

 

 

| Plant development

 

Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium
Alon Israeli, Yogev Burko, Sharona Shleizer-Burko, Iris Daphne Zelnik, Noa Sela, Mohammad R. Hajirezaei, Alisdair R. Fernie, Takayuki Tohge, Naomi Ori, Maya Bar

 

Cortical microtubule remodelling during strigolactone- and light-mediated growth inhibition of Arabidopsis hypocotyls
Yuliya A. Krasylenko, George Komis, Sonya Hlynska, Tereza Vavrdová, Miroslav Ovečka, Tomáš Pospíšil, Jozef Šamaj

 

The Arabidopsis TTL3 protein interconnects brassinosteroid signalling and cytoskeleton during lateral root development
Pengfei Xin, Jakub Schier, Ivan Kulich, Joseph G. Dubrovsky, Vielle-Calzada Jean-Philippe, Aleš Soukup

 

Hexose fluxes, mediated by vacuolar SWEET transporters, are important for xylem development in the inflorescence stem of Arabidopsis thaliana
Emilie Aubry, Beate Hoffmann, Françoise Vilaine, Françoise Gilard, Patrick A.W. Klemens, Florence Guérard, Bertrand Gakière, H. Ekkehard Neuhaus, Catherine Bellini, Sylvie Dinant, Rozenn Le Hir

 

Root electrotropism in Arabidopsis does not depend on auxin distribution, requires cytokinin and follows a power-law response curve
Nicholas Oliver, Maddalena Salvalaio, Deniz Tiknaz, Maximillian Schwarze, Nicolas Kral, Soo-Jeong Kim, Giovanni Sena

 

Arabidopsis embryos from Wang, et al.

 

Independent parental contributions initiate zygote polarization in Arabidopsis thaliana
Kai Wang, Houming Chen, Yingjing Miao, Yanfei Ma, Agnes Henschen, Jan U. Lohmann, Sascha Laubinger, Martin Bayer

 

Comparative Analysis of Embryo Proper and Suspensor Transcriptomes in Plant Embryos With Different Morphologies
Min Chen, Jer-Young Lin, Xiaomeng Wu, Nestor R. Apuya, Kelli F. Henry, Brandon H. Le, Anhthu Q. Bui, Julie M. Pelletier, Shawn Cokus, Matteo Pellegrini, John J. Harada, Robert B. Goldberg

 

A gene regulatory network critical for axillary bud dormancy directly controlled by Arabidopsis BRANCHED1
Sam W. van Es, Aitor Muñoz-Gasca, Francisco J. Romero-Campero, Eduardo González-Grandío, Pedro de los Reyes, Carlos Tarancón, Aalt D.J. van Dijk, Wilma van Esse, Gerco C. Angenent, Richard Immink, Pilar Cubas

 

Shoot-root interaction in control of camalexin exudation in Arabidopsis
Anna Koprivova, Vanessa Volz, Stanislav Kopriva

 

Organ geometry channels cell fate in the Arabidopsis ovule primordium
Elvira Hernandez-Lagana, Gabriella Mosca, Ethel Mendocilla Sato, Nuno Pires, Anja Frey, Alejandro Giraldo-Fonseca, Ueli Grossniklaus, Olivier Hamant, Christophe Godin, Arezki Boudaoud, Daniel Grimanelli, Daphné Autran, Célia Baroux

 

AINTEGUMENTA and AINTEGUMENTA-LIKE6 directly regulate floral homeotic and growth genes in young flowers
Beth A. Krizek, Alexis T. Bantle, Jorman M. Heflin, Han Han, Nowlan H. Freese, Ann E. Loraine

 

The SYP123-VAMP727 SNARE complex is involved in the delivery of inner cell wall components to the root hair shank in Arabidopsis
Tomoko Hirano, Kazuo Ebine, Takashi Ueda, Takumi Higaki, Takahiro Nakayama, Hiroki Konno, Hisako Takigawa-Imamura, Masa H. Sato

 

Blocking plasmodesmata in specific phloem cell types reduces axillary bud growth in Arabidopsis thaliana
Andrea Paterlini, Delfi Dorussen, Franziska Fichtner, Martin van Rongen, Ruth Delacruz, Ana Vojnović, Yrjö Helariutta, Ottoline Leyser

 

Lateral roots in Schütz, et al.

 

Integration of Cell Growth and Asymmetric Division During Lateral Root Initiation In Arabidopsis thaliana
Lilli Marie Schütz, Marion Louveaux, Amaya Vilches Barro, Sami Bouziri, Lorenzo Cerrone, Adrian Wolny, Anna Kreshuk, Fred A. Hamprecht, Alexis Maizel

 

A novel family of secreted insect proteins linked to plant gall development
Aishwarya Korgaonkar, Clair Han, Andrew L. Lemire, Igor Siwanowicz, Djawed Bennouna, Rachel Kopec, Peter Andolfatto, Shuji Shigenobu, David L. Stern

 

Enhanced reproductive thermotolerance is associated with increased accumulation of flavonols in pollen of the tomato high-pigment 2 mutant
Nicolas Rutley, Golan Miller, Fengde Wang, Jeffrey F Harper, Gad Miller, Michal Lieberman Lazarovich

 

Chickpeas in Caballo, et al.

 

The SINGLE FLOWER (SFL) gene encodes a MYB transcription factor that regulates the number of flowers produced by the inflorescence of chickpea
Cristina Caballo, Ana Berbel, Raul Ortega, Juan Gil, Teresa Millán, Josefa Rubio, Francisco Madueño

 

Characterization of the single FERONIA homolog in Marchantia polymorpha reveals an ancestral role of CrRLK1L receptor kinases in regulating cell expansion and morphological integrity
Martin A. Mecchia, Moritz Rövekamp, Alejandro Giraldo-Fonseca, Dario Meier, Philippe Gadient, John L. Bowman, Ueli Grossniklaus

 

Interactions Between SQUAMOSA and SVP MADS-box Proteins Regulate Meristem Transitions During Wheat Spike Development
Kun Li, Juan M. Debernardi, Chengxia Li, Huiqiong Lin, Chaozhong Zhang, Jorge Dubcovsky

 

Nodal root diameter and node number in maize (Zea mays L.) interact to influence plant growth under nitrogen stress
Hannah M. Schneider, Jennifer T. Yang, Kathleen M. Brown, Jonathan P. Lynch

 

Maize (Zea mays L.) nucleoskeletal proteins regulate nuclear envelope remodeling and function in stomatal complex development and pollen viability.
JF McKenna, HK Gumber, ZM Turpin, AM Jalovec, AC Kartick, K Graumann, HW Bass

 

Mutation of the nuclear pore complex component, aladin1, disrupts asymmetric cell division in Zea mays (maize)
Norman B. Best, Charles Addo-Quaye, Bong-Suk Kim, Clifford F. Weil, Burkhard Schulz, Guri Johal, Brian P. Dilkes

 

Ribosome profiling elucidates the contribution of differential translation to differential gene expression in bundle sheath and mesophyll cells in maize
Prakitchai Chotewutmontri, Alice Barkan

 

Regulation of the plastochron by three MANY-NODED DWARF genes in barley
Ken-ichiro Hibara, Masayuki Miya, Sean Akira Benvenuto, Naoko Hibara-Matsuo, Manaki Mimura, Takanori Yoshikawa, Masaharu Suzuki, Makoto Kusaba, Shin Taketa, Jun-ichi Itoh

 

Control of the Azolla symbiosis sexual reproduction: ferns to shed light on the origin of floral regulation?
Laura W. Dijkhuizen, Badraldin Ebrahim Sayed Tabatabaei, Paul Brouwer, Niels Rijken, Valerie A. Buijs, Erbil Güngör, Henriette Schluepmann

 

A molecular toolkit for the green seaweed Ulva mutabilis
Jonas Blomme, Xiaojie Liu, Thomas B. Jacobs, Olivier De Clerck

 

 

 

Evo-devo & evo

 

Evolution of lbx spinal cord expression and function
José L. Juárez-Morales, Frida Weierud, Samantha England, Celia Denby, Nicole Santos, Sylvie Mazan, Katharine E. Lewis

 

Ant pupae from Pontieri, et al.

 

From egg to adult: a developmental table of the ant Monomorium pharaonis
Luigi Pontieri, Arjuna Rajakumar, Ab Matteen Rafiqi, Rasmus Stenbak Larsen, Ehab Abouheif, Guojie Zhang

 

Skinks from Smith-Paredes, et al.

 

Hidden limbs in the “limbless skink” Brachymeles lukbani: developmental observations
Daniel Smith-Paredes, Oliver Griffith, Matteo Fabbri, Laurel Yohe, Daniel G. Blackburn, Cameron D. Siler, Bhart-Anjan S. Bhullar, Günter P. Wagner

 

Decidual cell differentiation is evolutionarily derived from fibroblast activation
Longjun Wu, Daniel J Stadtmauer, Jamie Maziarz, Gunter Wagner

 

Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing
Jason S Presnell, William E Browne

 

Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution
Spenser S. Smith, Daniel Chu, Tiange Qu, Richard A. Schneider

 

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, James P. Reddington, Charles Girardot, Eileen E. M. Furlong, Marc Robinson-Rechavi

 

Baby makes three: maternal, paternal, and zygotic genetic effects shape larval phenotypic evolution
Christina Zakas, Matthew V. Rockman

 

Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity
Rachel A. Johnston, Philippe Vullioud, Jack Thorley, Henry Kirveslahti, Leyao Shen, Sayan Mukherjee, Courtney Karner, Tim Clutton-Brock, Jenny Tung

 

Gene family evolution underlies cell type diversification in the hypothalamus of teleosts
Maxwell E.R. Shafer, Ahilya N. Sawh, Alexander F. Schier

 

Dog color patterns explained by modular promoters of ancient canid origin
Danika L. Bannasch, Christopher B. Kaelin, Anna Letko, Robert Loechel, Petra Hug, Vidhya Jagannathan, Jan Henkel, Petra Roosje, Marjo K. Hytönen, Hannes Lohi, Meharji Arumilli, DoGA consortium, Katie M. Minor, James R. Mickelson, Cord Drögemüller, Gregory S. Barsh, Tosso Leeb

 

Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas
Yotam Voskoboynik, Aidan Glina, Mark Kowarsky, Chiara Anselmi, Norma F Neff, Katherine J Ishizuka, Karla J Palmeri, Benyamin Rosental, Tal Gordon, Stephen R Quake, Irving L Weissman, Rachel Ben-Shlomo, Debashis Sahoo, Ayelet Voskoboynik

 

 

Cell biology

 

Fly neuroblasts from Sunchu, et al.

 

Asymmetric chromatin capture and nuclear envelopes separate endogenous and ectopic chromosomes after induced cell fusion
Bharath Sunchu, Nicole Lee, Roberto Carlos Segura, Clemens Cabernard

 

Moss bicentrioles from Gomes Pereira, et al.

 

The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles
Sónia Gomes Pereira, Ana Laura Sousa, Catarina Nabais, Tiago Paixão, Alexander J. Holmes, Martin Schorb, Gohta Goshima, Erin M. Tranfield, Jörg D. Becker, Mónica Bettencourt-Dias

 

IFT88 transports Gucy2d, a guanylyl cyclase, to maintain sensory cilia function in Drosophila
Sascha Werner, Sihem Zitouni, Pilar Okenve-Ramos, Susana Mendonça, Anje Sporbert, Christian Spalthoff, Martin C. Göpfert, Swadhin Chandra Jana, Mónica Bettencourt-Dias

 

Plk4 triggers autonomous de novo centriole biogenesis and maturation
Catarina Nabais, Delphine Pessoa, Jorge de-Carvalho, Thomas van Zanten, Paulo Duarte, Satyajit Mayor, Jorge Carneiro, Ivo A. Telley, Mónica Bettencourt-Dias

 

Novel roles for BicD in pronuclear fusion and meiosis II progression via localization of the CHC/TACC/Msps complex to MII spindles
Paula Vazquez-Pianzola, Dirk Beuchle, Gabriela Saro, Greco Hernández, Giovanna Maldonado, Dominique Brunßen, Peter Meister, Beat Suter

 

Cytoplasmic Microtubule Organizing Centers Regulate Meiotic Spindle Positioning in Mouse Oocyte
Daniela Londono Vasquez, Katherine Rodriguez-Lukey, Susanta K. Behura, Ahmed Z. Balboula

 

A small increase in CHEK1 activity leads to the arrest of the first zygotic division in human
Beili Chen, Jianying Guo, Ting Wang, Qianhui Lee, Jia Ming, Fangfang Ding, Haitao Li, Zhiguo Zhang, Lin Li, Yunxia Cao, Jie Na

 

BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes
Laura Bel Borja, Flavie Soubigou, Samuel J.P. Taylor, Conchita Fraguas Bringas, Jacqueline Budrewicz, Pablo Lara-Gonzalez, Christopher G. Sorensen Turpin, Joshua N. Bembenek, Dhanya K. Cheerambathur, Federico Pelisch

 

Lamin regulates the dietary restriction response via the mTOR pathway in Caenorhabditis elegans
Chayki Charar, Sally Metsuyanim-Cohen, Yosef Gruenbaum, Daniel Z Bar

 

A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia
Tooba Quidwai, Emma A. Hall, Margaret A. Keighren, Weihua Leng, Petra Kiesel, Jonathan N. Wells, Laura C. Murphy, Joseph A. Marsh, Gaia Pigino, Pleasantine Mill

 

 

Cell patterning by secretion-induced plasma membrane flows
Veneta Gerganova, Iker Lamas, David M. Rutkowski, Aleksandar Vještica, Daniela Gallo Castro, Vincent Vincenzetti, Dimitrios Vavylonis, Sophie G Martin

 

Centrosome-dependent microtubule organization sets the conditions for axon formation
Durga Praveen Meka, Oliver Kobler, Souhaila Wuesthoff, Birgit Schwanke, Christoph Krisp, Nessa Schmuelling, René Rueter, Tabitha Ruecker, Hartmut Schlüter, Eugenio F. Fornasiero, Froylan Calderon de Anda

 

 

 

Modelling

 

Modelling gene expression boundaires with Liu Perkins

 

Dynamic positioning and precision of bistable gene expression boundaries through diffusion and morphogen decay
Melinda Liu Perkins

 

Shaping the Epigenetic Landscape: Complexities and Consequences
Megan A. Coomer, Lucy Ham, Michael P. H. Stumpf

 

Time and Space in Segmentation
Erik Clark

 

The role of mechanical interactions in EMT
Ryan J. Murphy, Pascal R. Buenzli, Tamara A. Tambyah, Erik W. Thompson, Honor J. Hugo, Ruth E. Baker, Matthew J. Simpson

 

Exchange of molecular and cellular information: a hybrid model that integrates stem cell divisions and key regulatory interactions
Lisa Van den Broeck, Ryan J. Spurney, Adam P. Fisher, Michael Schwartz, Natalie M. Clark, Thomas T. Nguyen, Imani Madison, Mariah Gobble, Terri Long, Rosangela Sozzani

 

The basal level of gene expression associated with chromatin loosening shapes Waddington landscapes and controls cell differentiation
Gilles Flouriot, Charly Jehanno, Yann Le Page, Pascale Le Goff, Benjamin Boutin, Denis Michel

 

 

 

Tools & resources

 

CeLaVi: An Interactive Cell Lineage Visualisation Tool
Irepan Salvador-Martínez, Marco Grillo, Michalis Averof, Maximilian J. Telford

 

Integrating central and peripheral neurons in elongating multi-lineage-organized gastruloids
Zachary T. Olmsted, Janet L. Paluh

 

Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish
Marion Rosello, Juliette Vougny, François Czarny, Maria Caterina Mione, Jean-Paul Concordet, Shahad Albadri, Filippo Del Bene

 

Whole-organism eQTL mapping at cellular resolution with single-cell sequencing
Eyal Ben-David, James Boocock, Longhua Guo, Stefan Zdraljevic, Joshua S. Bloom, Leonid Kruglyak

 

Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse
Maria Benavente-Diaz, Glenda Comai, Daniela Di Girolamo, Francina Langa, Shahragim Tajbakhsh

 

Generation of a new Tbx6-inducible reporter mouse line to trace presomitic mesoderm derivatives throughout development and in adults
Laurent Yvernogeau, Anna Klaus, Carina van Rooijen, Catherine Robin

 

Tissue-specific transcription factor target identification in the Caenorhabditis elegans epidermis using targeted DamID
Dimitris Katsanos, Michalis Barkoulas

 

Molecular topography of an entire nervous system
Seth R Taylor, Gabriel Santpere, Alexis Weinreb, Alec Barrett, Molly B. Reilly, Chuan Xu, Erdem Varol, Panos Oikonomou, Lori Glenwinkel, Rebecca McWhirter, Abigail Poff, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Steven J Cook, Alexander Abrams, Berta Vidal, Cyril Cros, Saeed Tavazoie, Nenad Sestan, Marc Hammarlund, Oliver Hobert, David M. Miller III

 

Hickey, et al.’s set up

 

Engineered Tissue Interfaces for in vitro and in vivo Regeneration
Ryan J. Hickey, Maxime Leblanc Latour, James L. Harden, Andrew E. Pelling

 

Functional tagging of endogenous proteins and rapid selection of cell pools (Rapid generation of endogenously tagged piwi in ovarian somatic sheath cells.)
Celine Marlin Andrews, Parthena Konstantinidou, Pavol Genzor, Daniel Stoyko, Alexandra R. Elchert, Leif Benner, Sushil Sobti, Esther Y. Katz, Qingcai Meng, Astrid D. Haase

 

X-ray microscopy enables multiscale high-resolution 3D imaging of plant cells, tissues, and organs
Keith E Duncan, Kirk J Czymmek, Ni Jiang, August C. Thies, Christopher N. Topp

 

CellExplorer: a graphical user interface and a standardized pipeline for visualizing and characterizing single neurons
Peter C. Petersen, Joshua H. Siegle, Nicholas A. Steinmetz, Sara Mahallati, György Buzsáki

 

Engineering large chromosomal deletions by CRISPR-Cas9
Thomas F. Eleveld, Chaimaa Bakali, Paul P. Eijk, Phylicia Stathi, Pino J Poddighe, Bauke Ylstra

 

ZeBraInspector, a platform for the automated segmentation and analysis of body and brain volumes in whole 5 dpf zebrafish following simultaneous visualization with identical orientations
Sylvain Lempereur, Matthieu Simion, Elodie Machado, Fabrice Licata, Lilian Buzer, Isabelle Robineau, Julien Hémon, Payel Banerjee, Noémie De Crozé, Marc Léonard, Pierre Affaticati, Arnim Jenett, Hugues Talbot, Jean-Stéphane Joly

 

A versatile automated high-throughput drug screening platform for zebrafish embryos
Alexandra Lubin, Jason Otterstrom, Yvette Hoade, Ivana Bjedov, Eleanor Stead, Matthew Whelan, Gaia Gestri, Yael Paran, Elspeth Payne

 

MAPPER: A new image analysis pipeline unmasks differential regulation of Drosophila wing features
Nilay Kumar, Francisco Huizar, Trent Robinett, Keity J. Farfán-Pira, Dharsan Soundarrajan, Maria Unger, Pavel Brodskiy, Marcos Nahmad, Jeremiah J. Zartman

 

Automated hiPSC culture and sample preparation for 3D live cell microscopy
Mackenzie E. Coston, Benjamin W. Gregor, Joy Arakaki, Antoine Borensztejn, Thao P. Do, Margaret A. Fuqua, Amanda Haupt, Melissa C. Hendershott, Winnie Leung, Irina A. Mueller, Angelique M. Nelson, Susanne M. Rafelski, Madison J. Swain-Bowden, W. Joyce Tang, Derek J. Thirstrup, Winfried Wiegraebe, Calysta Yan, Ruwanthi N Gunawardane, Nathalie Gaudreault

 

A Golgi-localized peptide encoded by the CENP-R transcript provides a valuable tool for live cell imaging
Alexandra P. Navarro, Iain M. Cheeseman

 

The Allen Cell and Structure Segmenter: a new open source toolkit for segmenting 3D intracellular structures in fluorescence microscopy images
Jianxu Chen, Liya Ding, Matheus P. Viana, HyeonWoo Lee, M. Filip Sluezwski, Benjamin Morris, Melissa C. Hendershott, Ruian Yang, Irina A. Mueller, Susanne M. Rafelski

 

A semi-automated organoid screening method demonstrates epigenetic control of intestinal epithelial differentiation
Jenny Ostrop, Rosalie Zwiggelaar, Marianne Terndrup Pedersen, François Gerbe, Korbinian Bösl, Håvard T. Lindholm, Alberto Díez-Sánchez, Naveen Parmar, Silke Radetzki, Jens Peter von Kries, Philippe Jay, Kim B. Jensen, Cheryl Arrowsmith, Menno J. Oudhoff

 

Mouse brains from

 

Transcriptome analysis for the development of cell-type specific labeling to study olfactory circuits
Anzhelika Koldaeva, Cary Zhang, Yu-Pei Huang, Janine Reinert, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Taha Soliman, Hiroaki Matsunami, Izumi Fukunaga

 

Visualizing subcellular structures in neurons with expansion microscopy
Logan A. Campbell, Katy E. Pannoni, Niesha A. Savory, Dinesh Lal, Shannon Farris

 

Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects
Ju-Hyun Lee, Hyogeun Shin, Mohammed R. Shaker, Hyun Jung Kim, June Hoan Kim, Namwon Lee, Minjin Kang, Subin Cho, Tae Hwan Kwak, Jong Woon Kim, Mi-Ryong Song, Seung-Hae Kwon, Dong Wook Han, Sanghyuk Lee, Se-Young Choi, Im Joo Rhyu, Hyun Kim, Dongho Geum, Il-Joo Cho, Woong Sun

 

Scalable production of tissue-like vascularised liver organoids from human PSCs
Sean P Harrison, Richard Siller, Yoshiaki Tanaka, Yangfei Xiang, Benjamin Patterson, Henning Kempf, Espen Melum, Kathrine S Åsrud, Maria E Chollet, Elisabeth Andersen, Per Morten Sandset, Saphira Baumgarten, Flavio Bonanini, Dorota Kurek, Santosh Mathapati, Runar Almaas, Kulbhushan Sharma, Steven R Wilson, Frøydis S Skottvoll, Ida C Boger, Inger L Bogen, Tuula A Nyman, Jun J Wu, Ales Bezrouk, Dana Cizkova, Jaroslav Mokry, Robert Zweigerdt, In-Hyun Park, Gareth J Sullivan

 

InsectBrainDatabase – A unified platform to manage, share, and archive morphological and functional data
Stanley Heinze, Basil el Jundi, Bente G. Berg, Uwe Homberg, Randolf Menzel, Keram Pfeiffer, Marie Dacke, Eric Warrant, Gerit Pfuhl, Jürgen Rybak, Kevin Tedore

 

An Optimized CRISPR/Cas9 Approach for Precise Genome Editing in Neurons
Huaqiang Fang, Alexei M. Bygrave, Richard H. Roth, Richard C. Johnson, Richard L. Huganir

 

 

Research practice & education

 

League of Brazilian Bioinformatics: a competition framework to promote scientific training
L. M. Carvalho, N. A. R. Coimbra, M. R. C. Neves, N. J. Fonseca, M. A. Costa, E. C. A. Horacio, R. Riyuzo, F. F. Aburjaile, S. T. Nagamatsu

 

Active learning tools improve the learning outcomes, scientific attitude and critical thinking in higher education: Experiences in an online course during the COVID-19 pandemic
Izadora Volpato Rossi, Jordana Dinorá de Lima, Bruna Sabatke, Maria Alice Ferreira Nunes, Graciela Evans Ramirez, Marcel Ivan Ramirez

 

Design, construction, and advantages of 100% online laboratories in an upper division undergraduate biology course
Emma Brady, Shalaunda Reeves, Malcolm Maden, Brian D. Harfe

 

Democratising “Microscopi”: a 3D printed automated XYZT fluorescence imaging system for teaching, outreach and fieldwork
Matthew Wincott, Andrew Jefferson, Ian M. Dobbie, Martin J. Booth, Ilan Davis, Richard M. Parton

 

A Reaction Norm Perspective on Reproducibility
Bernhard Voelkl, Hanno Würbel

 

The 100,000 most influential scientists rank: the underrepresentation of Brazilian women in academia
Leticia de Oliveira, Fernanda Reichert, Eugenia Zandona, Rossana C. Soletti, Fernanda Staniscuaski

 

How accurate are citations of frequently cited papers in biomedical literature?
V Pavlovic, T Weissgerber, D Stanisavljevic, T Pekmezovic, V Garovic, N Milic, CITE Investigators

 

Evolving Structure and Diversity of Human Narratives in the Journal of Stories in Science
Reilly Q. Mach, Jessica W. Tsai, Fanuel J. Muindi

 

Knowledge and attitudes among life scientists towards reproducibility within journal articles: a research survey
Evanthia Kaimaklioti Samota, Robert P. Davey

 

Historical and cross-disciplinary trends in the biological and social sciences reveal an accelerating adoption of advanced analytics
Taylor Bolt, Jason S. Nomi, Danilo Bzdok, Lucina Q. Uddin

 




Thumbs down (1 votes)
Loading...

Tags:
Categories: Highlights

Leave a Reply

Your email address will not be published. Required fields are marked *

Get involved

Create an account or log in to post your story on the Node.

Sign up for emails

Subscribe to our mailing lists.

Contact us

Do you have a question or suggestion for the Node?