Xiao-Feng Zhao, Rafi Kohen, Eljo Y. Van Battum, Ying Zeng, Xiaolu Zhang, Craig N. Johnson, Karen Wang, Brian C. Lim, Juan A. Oses-Prieto, Joshua M. Rasband, Alma L. Burlingame, R. Jeroen Pasterkamp, Matthew N. Rasband, Roman J. Giger

Wnt pathway modulation is required to correctly execute multiple independent cellular dynamic programs during cranial neural tube closure

Amber Huffine Bogart, Eric R. Brooks

From Bogart et al. This image is made available under a CC-BY-NC 4.0 International license.

TEAD promotes lineage progression of subpallial neural progenitor cells independent of YAP/TAZ

Charles H Perry, Alfonso Lavado, Venkata Thulabandu, Cody Ramirez, Joshua Pare, Rajiv Dixit, Akhilesh Mishra, Jiyuan Yang, Jiyang Yu, Xinwei Cao

Left-right cortical interactions drive intracellular pattern formation in the ciliate Tetrahymena

Chinkyu Lee, Ewa Joachimiak, Wolfgang Maier, Yu-Yang Jiang, Karl F. Lechtreck, Eric S. Cole, Jacek Gaertig

Marsupial limb patterning redefines the necessity of lateral plate mesoderm subdivision for limb formation

Axel H Newton, Alexandra Leggatt, Ella R Farley, Karen E Sears, Aidan MC Couzens, Sara Ord, Andrew J Pask

Spatially ordered zygotic genome activation fulfills embryo quality control

Wenchao Qian, Hui Chen, Hongju Lee, Matthew C. Good

| Morphogenesis & mechanics

Role Of Pcdh15 In The Development Of Intrinsic Polarity Of Inner Ear Hair Cells

Raman Kaushik, Shivangi Pandey, Anubhav Prakash, Takaya Abe, Hiroshi Kiyonari, Raj K. Ladher

Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress

Mitzy A. Cowdin, Tuli Pramanik, Shelby R. Mohr-Allen, Yuting Fu, Austin Mills, Victor D. Varner, George E. Davis, Ondine Cleaver

From Cowdin et al. This image is made available under a CC-BY 4.0 International license.

Engineering kidney developmental trajectory using culture boundary conditions

Aria Zheyuan Huang, Louis S. Prahl, Karen Xu, Robert L. Mauck, Alex J. Hughes

Adhesion-Controlled Mechanics of the Glial Niche Regulate Neural Stem Cell Proliferative Potential

Anna Segú Cristina, David Briand, Aman Kukde, Emeline Perthame, Stéphane Rigaud, Jean-Yves Tinevez, Agata Banach-Latapy, Nick D.L. Owens, Léo Valon, Yohanns Bellaïche, Pauline Spéder

Morphogenetic constrains in the development of gastruloids: implications for mouse gastrulation

Ulla-Maj Fiuza, Sara Bonavia, Pau Pascual-Mas, Gabriel Torregrosa-Cortes, Pablo Casani-Galdon, Gaelle Robertson, Andre Dias, Alfonso Martinez Arias

Local activation of Cxcl12a signaling controls olfactory placode morphogenesis in zebrafish embryos

Marie Zilliox, Gaëlle Letort, David Sanchez, Christian Rouviere, Pascale Dufourcq, Frédérique Gaits-Iacovoni, Anne Pizzoccaro, Violaine Roussier-Michon, Patrick Blader, Julie Batut

Developmental delay ensures global tissue size robustness upon local induction of apoptosis

Ralitza Staneva, Gabriel Sobczyk-Moran, Florence Levillayer, Alexis Villars, Anđela Davidović, Romain Levayer

Size-dependent temporal decoupling of morphogenesis and transcriptional programs in gastruloids

Isma Bennabi, Pauline Hansen, Melody Merle, Judith Pineau, Lucille Lopez-Delisle, Dominique Kolly, Denis Duboule, Alexandre Mayran, Thomas Gregor

Kcnb1-Kcng4 axis regulates Scospondin secretion and Reissner fiber development

Rasieh Amini, Ruchi P. Jain, Vladimir Korzh

From Amini et al. This image is made available under a CC-BY 4.0 International license.

| Genes & genomes

Pleiotropic function of Dlx5/6 in coordinating the development of mammalian vocal and auditory organs

Frida Sanchez-Garrido, Victoria Bouzerand, Marketa Kaiser, Chloe Chaumeton, Anastasia Fontaine, Tomas Zikmund, Jozef Kaiser, Eglantine Heude

Midfacial retrusion and loss of facial appendages caused by mutation of Pax9 in zebrafish

Sandhya Paudel, Sarah McLeod, Stefani Gjorcheska, Lindsey Barske

Mammalian heat shock protein A4 family ortholog Hsc70Cb is required for two phases of spermatogenesis in D. melanogaster

Brendan J Houston, Joseph Nguyen, Richard Burke, Andre Nogueira Alves, Gary R Hime, Moira K O’Bryan

tet2 and tet3 regulate cell fate specification and differentiation events during retinal development

Shea A Heilman, Hannah C Schriever, Dennis Kostka, Kristen M Koenig, Jeffrey M Gross

Single-Cell full-length Isoform Sequencing Unveils Transcriptional Dysregulation in Autism Spectrum Disorder During Cerebral Cortex Development

Xiaoyi Xu, Jun Wang, Kunhua Hu, Dan Su, Qingpei Huang, Xiaotang Fan, Xiaoying Fan

Analysis of gene expression in Aedes aegypti suggests changes in early genetic control of mosquito development

Renata Coutinho-dos-Santos, Daniele G. Santos, Lupis Ribeiro, Jonathan J. Mucherino-Muñoz, Marcelle Uhl, Carlos Logullo, A Mendonça-Amarante, M Fantappie, Rodrigo Nunes-da-Fonseca

Differential Expression of Edar and Xedar During Mouse and Rat Tail Appendage Development

Slawomir A. Wisniewski

RNA sequencing reveals the developmental onset of autosomal gene expression differences in male and female extravillous trophoblasts

Matthew J. Shannon, Alexander G. Beristain

Divergent regulatory element programs steer sex-specific supporting cell differentiation along mouse gonadal development

Isabelle Stévant, Elisheva Abberbock, Meshi Ridnik, Roni Weiss, Linoy Swisa, Christopher R Futtner, Danielle Maatouk, Robin Lovell-Badge, Valeriya Malysheva, Nitzan Gonen

From Stévant et al. This image is made available under a CC-BY-NC 4.0 International license.

| Stem cells, regeneration & disease modelling

Adipose-derived Mesenchymal Stem Cells and Retinal Pigment Epithelial Cells Interactions in Stress Environment via Tunneling Nanotubes

Merve Gozel, Karya Senkoylu, Cem Kesim, Murat Hasanreisoglu

Dynamic cell fate plasticity and tissue integration drive functional synovial joint regeneration

Maria Blumenkrantz, Felicia Woron, Ernesto Gagarin, Everett Weinstein, Maryam H Kamel, Leonardo Campos, Agnieszka Geras, Troy Anderson, Julia Mo, Desmarie Sherwood, Maya Gwin, Bianca Dumitrascu, Nadeen O Chahine, Joanna Smeeton

Origin of Chromosome 12 Trisomy Surge in Human Induced Pluripotent Stem Cells (iPSCs)

Maria Narozna, Megan C. Latham, Gary J. Gorbsky

A spreading, multi-tissue wound signal initiates whole-body regeneration

Catriona Breen, Mansi Srivastava

From Breen et al. This image is made available under a CC-BY-NC-ND 4.0 International license.

Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells

Luca Caputo, Cedomir Stamenkovic, Matthew T. Tierney, Maria Sofia Falzarano, Rhonda Bassel-Duby, Alessandra Ferlini, Eric N. Olson, Pier Lorenzo Puri, Alessandra Sacco

Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration

Rachel Forman-Rubinsky, Wei Feng, Brent T. Schlegel, Angela Paul, Daniel Zuppo, Katarzyna Kedziora, Donna Stoltz, Simon Watkins, Dhivyaa Rajasundaram, Guang Li, Michael Tsang

Transcriptomic Landscape and Immune Microenvironment Around Wound Bed Define Regenerative versus Non-regenerative Outcomes in Mouse Digit Amputation

Archana Prabahar, Connie S. Chamberlain, Ray Vanderby, William L. Murphy, William Dangelo, Kulkarni Mangesh, Bryan Brown, Barsanjit Mazumder, Stephen Badylak, Peng Jiang

Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration

Byron W.H. Mui, Joseph Y. Wong, Toni Bray, Lauren Connolly, Jia Hua Wang, Alexander Winkel, Pamela G. Robey, Kristian Franze, Kevin J. Chalut, Mekayla A. Storer

Differentiation of Mesenchymal Stem/ Stromal Cells into CD45+ Macrophage-like Cells: Expanding Insights into MSC Plasticity

Robert M. Rusch, Yo Mabuchi, Satoru Morikawa, Yoko Ogawa, Shigeto Shimmura

Spatiotemporal analysis of dystrophin expression during muscle repair

John C.W. Hildyard, Liberty E. Roskrow, Dominic J. Wells, Richard J. Piercy

Generation of iPSC line ERCi004-A from human dermal fibroblasts of a patient with maturity-onset diabetes of the young type 3 caused by a heterozygous mutation in the HNF1A gene

Asya Bastrich, Daniil Antonov, Aleksandra Podzhilkova, Darya A. Petrova, Svetlana V. Pylina, Dmitriy N. Laptev, Elena A. Sechko, Sergey N. Kuznetsov, Ekaterina A. Vetchinkina, Natalia G. Mokrysheva

Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity

Jules A. Granet, Rebecca Robertson, Romina L. Filippelli, Alessio Cusmano, Shulei Li, Moein Yaqubi, Jo Anne Stratton, Natasha C. Chang

Rejuvenating aged osteoprogenitors for bone repair

Joshua Reeves, Pierre Tournier, Pierre Becquart, Robert Carton, Yin Tang, Alessandra Vigilante, Dong Fang, Shukry J Habib

Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models

Ruiqi Hu, Linda L. Boshans, Bohan Zhu, Peiwen Cai, Yiran Tao, Mark Youssef, Gizem Inak Girrbach, Yingnan Song, Xuran Wang, Alexander Tsankov, Joseph D. Buxbaum, Sai Ma, Nan Yang

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, Ella Thomson, Tülin Tatar, Douglas Colby, Man Zhang, Ian Chambers

PDGFRα+ Mesenchymal Stromal Cells Contribute to Epithelial Lineages during Prostate Development

Dibyo Maiti, Hsin-Jung Tien, Purna A. Joshi

A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient

James P. Cleland, Hanh T.-K. Vu, Johanna E. M. Dickmann, Andrei Rozanski, Steffen Werner, Andrea Schuhmann, Anna Shevchenko, Jochen C. Rink

PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation

Manxi Zheng, Qinlu Peng, Erin M Kropp, Zhejuan Shen, Suxuan Liu, Zhengyou Yin, Sho Matono, Takao Iwawaki, Xiang Wang, Ken Inoki, Yang Mei, Qing Li, Lu Liu

Modelling co-development between the somites and neural tube in human Trunk-like Structures (hTLS)

Komal Makwana, Louise Tilley, Probir Chakravarty, Jamie Thompson, Peter Baillie-Benson, Ignacio Rodriguez-Polo, Naomi Moris

Establishment of bovine extraembryonic endoderm cells

Hao Ming, Giovanna N. Scatolin, Alejandro Ojeda, Zongliang Jiang

TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cells

Young Woo Eom, Ju-Eun Hong, Pil Young Jung, Yongdae Yoon, Sang-Hyeon Yoo, Jiyun Hong, Ki-Jong Rhee, Bhupendra Regmi, Saher Fatima, Moon Young Kim, Soon Koo Baik, Hye Youn Kwon

Neuronal activation in the axolotl brain promotes spinal cord regeneration

SE Walker, K Yu, S Burgess, K Echeverri

Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration

Georgios Tsissios, Marion Leleu, Kelly Hu, Alp Eren Demirtas, Hanrong Hu, Toru Kawanishi, Evangelia Skoufa, Alessandro Valente, Antonio Herrera, Adrien Mery, Lorenzo Noseda, Haruki Ochi, Selman Sakar, Mikiko Tanaka, Fides Zenk, Can Aztekin

From Tsissios et al. This image is made available under a CC-BY-NC 4.0 International license.

Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells

Jielin Yan, Renhe Luo, Bess P. Rosen, Dingyu Liu, Wilfred Wong, Christina S Leslie, Danwei Huangfu

YAP regulates periosteal expansion in fracture repair

Madhura P Nijsure, Brendan Tobin, Dakota L Jones, Annemarie Lang, Grey Hallström, Miriam Baitner, Gabrielle I Tanner, Yasaman Moharrer, Christopher J Panebianco, Elizabeth G Seidl, Nathaniel A Dyment, Gregory L Szeto, Levi Wood, Joel D Boerckel

Injury-induced Neuregulin-ErbB signaling from muscle mobilizes stem cells for whole-body regeneration in Acoels

Brian Stevens, Riley Popp, Heather Valera, Kyle Krueger, Christian P. Petersen

Organ injury accelerates stem cell differentiation by modulating a fate-transducing lateral inhibition circuit

Erin N. Sanders, Hsuan-Te Sun, Saman Tabatabaee, Charles F. Lang, Sebastian G. van Dijk, Yu-Han Su, Andrew LaboD, Javeria Idris, Marco Marchetti, Shicong Xie, Lucy Erin O’Brien

| Plant development

Genes and pathways determining flowering time variation in temperate adapted sorghum

Harshita Mangal, Kyle Linders, Jonathan Turkus, Nikee Shrestha, Blake Long, Xianyan Kuang, Ernest Cebert, J. Vladimir Torres-Rodriguez, James C Schnable

Developmental rewiring of the NGAL/CUC/KLU network associated with pleiotropic roles of NGAL genes

Antoine Nicolas, Panagiotis Papadopoulos, Matteo Caroulle, Bernard Adroher, Magali Goussot, Anne-Sophie Sarthou, Nicolas Arnaud, Aude Maugarny, Patrick Laufs

Effects of an auxin antagonist, PEO-IAA, and an auxin transport inhibitor, NPA, on gametophore development in Physcomitrium patens (Hedw.) Mitt

Shawn R Robinson, Neil W Ashton

The coordination of cell proliferation and cell-division orientation controls Arabidopsis radial style development

Iqra Jamil, Samuel W.H. Koh, Jitender Cheema, Laila Moubayidin

Relationship between concentration of cytokinin for efficient shoot regeneration and seed coat color in leaf lettuce

Mitsuhiro Kimura, Takeshi Yoshizumi

Apocarotenoid signaling regulates meristem activity and shapes shoot and root lateral organ formation in Arabidopsis

Julio Sierra, Lina Escobar-Tovar, Selene Napsucialy-Mendivil, Omar Oltehua-López, Joseph G. Dubrovsky, Ryan P. McQuinn, Patricia Leon

CLE4 peptide hormone regulates de novo shoot regeneration in potato

Maria Gancheva, Ludmila Lutova

Predictable modulation of plant root development using engineered cytokinin regulators

Rohan Rattan, Simon Alamos, Matthew Szarzanowicz, Kasey Markel, Patrick M. Shih

The unique morphological basis and parallel evolutionary history of personate flowers in Penstemon

Trinity H. Depatie, Carolyn A. Wessinger

CBAM-ResNet34-based classification and evaluation method for developmental processes of greenhouse strawberries

Jianxu Wang, Zhongyue Liang, Fengan Jiang, Jian Feng, Yuyang Xiao, Ming Yang, Deguang Wang

A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development

Joel Rodríguez Herrera, Kenia Aislinn Galván Alcaraz, Ramsés Uriel Albarrán Hernández, Juan Pablo Villa Núñez, Gustavo Rodríguez Alonso, Svetlana Shishkova

The MpANT-auxin loop modulates Marchantia polymorpha development

Melissa Dipp-Alvarez, J. Luis Lorenzo-Manzanarez, Eduardo Flores-Sandoval, Domingo Méndez-Álvarez, Annie Espinal-Centeno, Jesús León-Ruiz, Fernando Olvera-Martínez, John L. Bowman, Mario A. Arteaga-Vázquez, Alfredo Cruz-Ramírez

A female-specific RdDM-associated element guides de novo DNA methylation during rice gametophyte development

Taehoon Kim, Marcio F. R. Resende Jr., Meixia Zhao, Kevin Begcy

Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana

Mary Ngigi, Mather Khan, Ricarda Remus, Shishir K Gupta, Petra Bauer

Light quantity impacts early response to cold and cold acclimation in young leaves of Arabidopsis

Markéta Luklová, Marieke Dubois, Michaela Kameniarová, Klára Plačková, Jan Novák, Romana Kopecká, Michal Karady, Jaroslav Pavlů, Jan Skalák, Sunita Jindal, Ljiljana Tubić, Zainab Quddos, Ondřej Novák, Dirk Inzé, Martin Černý

Single-nuclei sequencing of Moricandia arvensis reveals bundle sheath cell function in the photorespiratory shuttle of C3-C4 intermediate Brassicaceae

Sebastian Triesch, Vanessa Reichel-Deland, José Miguel Valderrama Martín, Michael Melzer, Urte Schlüter, Andreas P.M. Weber

Mechanical stress orients stomata division to form tissue scale alignments

Leo Serra, Euan T. Smithers, Lucy Bentall, Martin O. Lenz, Sarah Robinson

Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature

Tomás Urzúa Lehuedé, Victoria Berdion Gabarain, Miguel Angel Ibeas, Hernan Salinas-Grenet, Romina Acha, Tomas Moyano, Lucia Ferrero, Gerardo Núñez-Lillo, Jorge Perez, Florencia Perotti, Virginia Natali Miguel, Fiorella Paola Spies, Miguel A. Rosas, Ayako Kawamura, Diana R. Rodríguez-García, Ah-Ram Kim, Trevor Nolan, Adrian A. Moreno, Keiko Sugimoto, Norbert Perrimon, Karen A. Sanguinet, Claudio Meneses, Raquel L. Chan, Federico Ariel, Jose M. Alvarez, José M. Estevez

The inner integument controls embryo sac development and seed shape in Arabidopsis thaliana

Tejasvinee Atul Mody, Kay Schneitz

From Mody et al. This image is made available under a CC-BY-NC-ND 4.0 International license.

Maize rough endosperm6 is a predicted RNA helicase required for miRNA processing and endosperm cell patterning

Tianxiao Yang, Masaharu Suzuki, L. Curtis Hannah, A. Mark Settles

Transcriptional shifts and microbiome dynamics in sorghum roots during vegetative growth under drought stress

Ahmad H. Kabir, Philip Brailey-Jones, Mostafa Abdelrahman, Jean Legeay, Bulbul Ahmed, Lam-Son Phan Tran, Jeffrey L. Bennetzen

Spatial Transcriptomics Reveals Expression Gradients in Developing Wheat Inflorescences at Cellular Resolution

Katie A. Long, Ashleigh Lister, Maximillian R. W. Jones, Nikolai M. Adamski, Rob E. Ellis, Carole Chedid, Sophie J. Carpenter, Xuemei Liu, Anna E. Backhaus, Andrew Goldson, Vanda Knitlhoffer, Yuanrong Pei, Martin Vickers, Burkhard Steuernagel, Gemy G. Kaithakottil, Jun Xiao, Wilfried Haerty, Iain C Macaulay, Cristobal Uauy

ELONGATED HYPOCOTYL 5 regulates light-mediated squalene biosynthesis and development in Arabidopsis thaliana

Pranshu Kumar Pathak, Aruba Khan, Ashish Sharma, Nivedita Singh, Gurpreet Sandhu, Prabodh Kumar Trivedi

The angiosperm seed life cycle follows a developmental reverse hourglass

Asif Ahmed Sami, Leónie Bentsink, Mariana A. S. Artur

Application of a GRF-GIF chimera enhances plant regeneration for genome editing in tomato

Gwen Swinnen, Eléonore Lizé, Miguel Loera Sánchez, Stéphanie Stolz, Sebastian Soyk

Sporophyte Directed Gametogenesis via the Ubiquitin Proteasome System

Prakash Sivakumar, Saurabh Pandey, A Ramesha, Jayeshkumar Narsibhai Davda, Aparna Singh, Chandan Kumar, Hardik Gala, Veeraputhiran Subbiah, Harikrishna Adicherla, Jyotsna Dhawan, L. Aravind, Imran Siddiqi

Morphological Plasticity and Reproductive Strategies of Kalanchoe Species in Invasive Spread

Zhe Zhang, Daisuke Sugiura, Wataru Yamori, Yanhong Tang

DOMON domain-containing proteins control root development upon phosphate deficiency and ammonium stress by modulating iron dynamics

Joaquín Clúa, Yves Poirier

Shoot nitrate status regulates Arabidopsis shoot growth and systemic transcriptional responses via shoot adenylate isopentenyltransferase 3

Kota Monden, Takamasa Suzuki, Mikiko Kojima, Yumiko Takebayashi, Daisuke Sugiura, Tsuyoshi Nakagawa, Hitoshi Sakakibara, Takushi Hachiya

| Evo-devo

Morphological and Molecular Phylogenetic Characterization of Three New Marine Goniomonad Species

Yasinee Phanprasert, Sun Young Kim, Nam Seon Kang, Minseok Jeong, Jong Im Kim, Woongghi Shin, Won Je Lee, Eunsoo Kim

Deep homology of a brachyury regulatory syntax and origin of the notochord

Tzu-Pei Fan, Jun-Ru Lee, Che-Yi Lin, Yi-Chih Chen, Ann E. Cutting, R. Andrew Cameron, Jr-Kai Yu, Yi-Hsien Su

From Fan et al. This image is made available under a CC-BY-NC-ND 4.0 International license.

Developmentally Incomplete Barb Rami Increased the Morphological Diversity of Early Feathers

Yanyun Zhang, Jiawei Tang, Ying Wang, Shuo Wang

Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily-ancient path to malignant growth

Zhe Chen, Xiaomeng Zhang, Mingxi Deng, Chongyang Li, Thi Thuy Nguyen, Min Liu, Kun Dou, Toyotaka Ishibashi, Jiguang Wang, Yan Yan

FLEXIBILITY IN GENE COEXPRESSION AT DEVELOPMENTAL AND EVOLUTIONARY TIMESCALES

Eva K Fischer, Youngseok Song, Wen Zhou, Kim L Hoke

Low mutation rate but high male-bias in the germline of a short-lived opossum

Yadira Peña-Garcia, Richard J. Wang, Muthuswamy Raveendran, R. Alan Harris, Paul B. Samollow, Jeffrey Rogers, Matthew W. Hahn

Structural and evolutionary features of red algal UV sex chromosomes

A.P Lipinska, G. Cossard, P. Epperlein, T. Woertwein, C. Molinier, O. Godfroy, S. Carli, L. Ayres-Ostrock, E Lavaut, F. Marchi, S. Mauger, C. Destombe, M.C. Oliveira, E.M. Plastino, S.A. Krueger-Hadfield, M.L. Guillemin, M. Valero, S.M. Coelho

Cis-Regulatory Evolution of CCNB1IP1 Driving Gradual Increase of Cortical Size and Folding in primates

Ting Hu, Yifan Kong, Yulian Tan, Pengcheng Ma, Jianhong Wang, Xuelian Sun, Kun Xiang, Bingyu Mao, Qingfeng Wu, Soojin V. Yi, Lei Shi

Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring

Alice M. Godden, Willian T.A.F. Silva, Berrit Kiehl, Cécile Jolly, Leighton Folkes, Ghazal Alavioon, Simone Immler

Do morphologically distinct groups correspond to reproductively isolated species? A case study in Myrmica ants from Switzerland

Guillaume Lavanchy, Christophe Galkowski, Kristine Jecha, Anne Freitag, Amaury Avril, Aline Dépraz, Tanja Schwander

Thermosensory neurons control genetic inheritance through regulation of germline transposons

Péter R. Szántó, David H. Meyer, Guy Teichman, Francy J. Pérez-Llanos, Daniel Rickert, Karl-Erich Köhrer, Oded Rechavi, Björn Schumacher

Perception of Temperature Even in the Absence of Actual Change is Sufficient to Drive Transgenerational Epigenetic Inheritance

Guy Teichman, Mor Sela, Chee Kiang Ewe, Itai Rieger, Sarit Anava, Yael Mor, Péter Szántó, David H. Meyer, Hila Doron, Or Shachar, Vladyslava Pechuk, Hila Gingold, Meital Oren-Suissa, Matthew McGee, Michael Shapira, Björn Schumacher, Oded Rechavi

Conserved interhemispheric morphogenesis in amniotes preceded the evolution of the corpus callosum

Ryota Noji, Mari Kaneko, Takaya Abe, Hiroshi Kiyonari, Yukihiro Nishikawa, Takuma Kumamoto, Hitoshi Gotoh, Chiaki Ohtaka-Maruyama, Katsuhiko Ono, Tatsuya Yoshizawa, Tadashi Nomura

Structural rearrangements and selection promote phenotypic evolution in Anolis lizards

Raul Araya Donoso, Sarah M Baty, Jamie E Johnson, Eris Lasku, Jody Taft, Rebecca Fisher, Jonathan B Losos, Greer Dolby, Kenro Kusumi, Anthony Geneva

Tracing of the developmental origin of the caudal fin muscle in zebrafish

Kinya G Ota, Gembu Abe

From Ota et al. This image is made available under a CC-BY 4.0 International license.

Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback

Florent Sylvestre, Nadia Aubin-Horth, Louis Bernatchez

Parallel evolution of LRP2 gene mediating telescope-eye and celestial-eye in goldfish

Rongni Li, Bo Zhang, Yansheng Sun, Jingyi Li

Differential expression of sex regulatory genes in gonads of Astyanax mexicanus surface fish and cavefish

Kaitlyn A. Webster, Bethany Ponte, Hans Vasquez-Gross, Juli Petereit, John Hutchinson, Misty R. Riddle

Targets of sexual selection on the Drosophila wing

Stephen P. De Lisle, Anneli Branden, Ellen Paajarvi Vag

Cell fate specification modes shape transcriptome evolution in the highly conserved spiral cleavage

Yan Liang, Jingcheng Wei, Yue Kang, Allan M. Carrillo-Baltodano, José M. Martín-Durán

Calcium dynamics tune developmental tempo to generate evolutionarily divergent axon tract lengths

Feline W. Lindhout, Hanna M. Szafranska, Ivan Imaz-Rosshandler, Luca Guglielmi, Maryam Moarefian, Kateryna Voitiuk, Natalia K. Zernicka-Glover, Daniel J. Lloyd-Davies Sánchez, John Minnick, Mircea Teodorescu, Madeline A. Lancaster

Cell Biology

Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells

Aleksandra Babicheva, Ibrahim Elmadbouh, Shanshan Song, Michael Thompson, Ryan Powers, Pritesh P. Jain, Amin Izadi, Jiyuan Chen, Lauren Yung, Sophia Parmisano, Cole Paquin, Wei-Ting Wang, Yuqin Chen, Ting Wang, Mona Alotaibi, John Y.-J. Shyy, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Y.S. Prakash, Christina M. Pabelick, Jason X.-J. Yuan

Isolation and manipulation of meiotic spindles from mouse oocytes reveals migration regulated by pulling force during asymmetric division

Ning Liu, Ryo Kawamura, Wenan Qiang, Ahmed Balboula, John F Marko, Huanyu Qiao

ANKRD5: a key component of the axoneme required for sperm motility and male fertility

Shuntai Yu, Guoliang Yin, Peng Jin, Weilin Zhang, Yingchao Tian, Xiaotong Xu, Tianyu Shao, Yushan Li, Fei Sun, Yun Zhu, Fengchao Wang

An RNAi screen of Rab GTPase genes in C. elegans reveals that somatic cells of the reproductive system depend on rab-1 for morphogenesis but not stem cell niche maintenance

Kayt Scott, Noor Singh, Kacy Lynn Gordon

Control of Epithelial Tissue Organization by mRNA Localization

Devon E. Mason, Thomas D. Madsen, Alexander N. Gasparski, Neal Jiwnani, Terry Lechler, Roberto Weigert, Ramiro Iglesias-Bartolome, Stavroula Mili

From Mason et al. This image is made available for use under a CC0 license.

Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila

Wei Qi Guinevere Sew, Zhiquan Li, Lene Juel Rasmussen, Héctor Herranz

Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division

Louis Cueff, Sylvain Pastezeur, Ewen Huet, Méline Coquil, Titouan Savary, Jacques Pécréaux, Hélène Bouvrais

Bouncer’s receptor on sperm: Investigating sperm-egg compatibility in fish

Andreas Blaha, Andrea Pauli

Developmentally regulated actin-microtubule crosstalk in Drosophila oogenesis

Wei-Chien Chou, Margot Lakonishok, Wen Lu, Vladimir I. Gelfand, Brooke M. McCartney

Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

Jessica Jocher, Philipp Janssen, Beate Vieth, Fiona C. Edenhofer, Tamina Dietl, Anita Térmeg, Johanna Geuder, Wolfgang Enard, Ines Hellmann

Glucose-6-phosphatase is required for organelle reorganization, energy metabolism and motility of Drosophila sperm

Sheida Hedjazi, Tetsuya Miyamoto, Ji-Eun Ahn, Raquel M. Sitcheran, Hubert Amrein

METTL7A improves bovine IVF embryo competence by attenuating oxidative stress

Linkai Zhu, Hao Ming, Giovanna N. Scatolin, Andrew Xiao, Zongliang Jiang

ABHD2 activity is not required for the non-genomic action of progesterone on human sperm

Oliver Arnolds, Eve M. Carter, Madison Edwards, Edvard Wigren, Evert Homan, Pauline Ribera, Kirsty Bentley, Martin Haraldsson, Nmesoma Theo-Emegano, Peter Loppnau, Magdalena M Szewczyk, Michelle A Cao, Dalia Barsyte-Lovejoy, Karen Vester, Anna Thrun, Alexandra Amaral, Ralf Lesche, Jens Münchow, W. Felix Zhu, Louisa Temme, Christoph Brenker, Timo Strünker, Michael Sundström, Matthew H. Todd, Aled M Edwards, Claudia Tredup, Opher Gileadi

The transcriptomic signature of age and sex is not conserved in human primary myocytes

Séverine Lamon, Megan Soria, Ross Williams, Annabel Critchlow, Andrew Garnham, Akriti Varshney, Traude Beillharz, Danielle Hiam, Mark Ziemann

The Chromosome Periphery is an Essential Compartment of Oocyte Chromosomes

Eva L Simpson, Ben Wetherall, Liam P Cheeseman, Aleksandra Byrska, Tania Mendonca, Xiaomeng Xing, Alison J Beckett, Helder Maiato, Alexandra Sarginson, Ian A Prior, Geraldine M Hartshorne, Andrew McAinsh, Suzanne Madgwick, Daniel G Booth

Tonic ERK signaling regulate the basal lactate production in prepubertal rat Sertoli cell

MUKESH GAUTAM, BHOLA SHANKAR PRADHAN, SUBEER S MAJUMDAR

The full length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice

Yan Huang, Nina Bucevic, Carmen Coves, Natalia Felipe-Medina, Marina Marcet-Ortega, Nikoleta Nikou, Cristina Madrid-Sandín, Maria Lopez-Panades, Carolina Buza, Neus Ferrer Miralles, Antoni Iborra, Anna Pujol, Alberto M Pendás, Ignasi Roig

MCL-1 regulates cellular transitions during oligodendrocyte development

Melanie Gil, Marina R Hanna, Vivian Gama

C. elegans LET-381/FoxF and DMD-4/DMRT control development of the mesodermal HMC endothelial cell

Nikolaos Stefanakis, Jasmine Xi, Jessica Jiang, Shai Shaham

Restoring oxidative phosphorylation enhances osteogenesis in mitochondrial DNA translation defective human bone marrow stromal cells

Paula Fernandez-Guerra, Pernille Kirkegaard Kjær, Simone Karlsson Terp, Jesper S. Thomsen, Blanca I. Aldana, Herma Renkema, Jan Smeitink, Per H. Andersen, Johan Palmfeldt, Kent Søe, Thomas L. Andersen, Moustapha Kassem, Morten Frost, Anja L. Frederiksen

Modelling

Learning geometric models for developmental dynamics

Addison Howe, Madhav Mani

Resolving the design principles that control postnatal vascular growth and scaling

Danielle Pi, Jonas Braun, Sayantan Dutta, Debabrata Patra, Pauline Bougaran, Ana Mompeón, Feiyang Ma, Stuart R Stock, Sharon Choi, Lourdes García-Ortega, Muhammad Yogi Pratama, Diomarys Pichardo, Bhama Ramkhelawon, Rui Benedito, Victoria L Bautch, David M Ornitz, Yogesh Goyal, M. Luisa Iruela-Arispe

Towards a mathematical framework for modelling cell fate dynamics

Sean T. Vittadello, Léo Diaz, Yujing Liu, Adriana Zanca, Michael P.H. Stumpf

Optimal network sizes for most robust Turing patterns

Hazlam S. Ahmad Shaberi, Aibek Kappassov, Antonio Matas-Gil, Robert G. Endres

Tools & Resources

In toto analysis of multicellular arrangement reduces embryonic tissue diversity to two archetypes that require specific cadherin expression

Max Brambach, Marvin Albert, Jérôme Julmi, Robert Bill, Darren Gilmour

The sev-GAL4 driver in Drosophila melanogaster does not express in the eight pairs of dorso-medial and some other neurons in larval ventral ganglia: A correction

Vanshika Kaushik, Subhash C. Lakhotia

The tendon differentiation program is activated in human adipose stromal cells embedded in a 3D-collagen matrix

Maxime Hordé, Jonathan Fouchard, Xavier Laffray, Cédrine Blavet, Véronique Béréziat, Claire Lagathu, Ludovic Gaut, Delphine Duprez, Emmanuelle Havis

“Imaging Translation in Early Embryo Development”

Pierre Bensidoun, Morgane Verbrugghe, Mounia Lagha

deepBlastoid: A Deep Learning-Based High-Throughput Classifier for Human Blastoids Using Brightfield Images with Confidence Assessment

Zejun Fan, Zhenyu Li, Yiqing Jin, Arun Pandian Chandrasekaran, Ismail M. Shakir, Yingzi Zhang, Aisha Siddique, Mengge Wang, Xuan Zhou, Yeteng Tian, Peter Wonka, Mo Li

The Effects of Heat Stress on the Ovary, Follicles and Oocytes: A Systematic Review

Luhan T. Zhou, Dilan Gokyer, Krystal Madkins, Molly Beestrum, Daniel E. Horton, Francesca E. Duncan, Elnur Babayev

Pre-oviposition development of the brown anole (Anolis sagrei)

Antonia Weberling, Natalia A. Shylo, Bonnie K. Kircher, Hannah Wilson, Melainia McClain, Marta Marchini, Katherine Starr, Thomas J. Sanger, Florian Hollfelder, Paul Trainor

From Weberling et al. This image is made available under a CC-BY-NC-ND 4.0 International license.

Advances in culturing of the sea star Patiria miniata

Vanessa Barone, Luisa Coronado, Deka Ismail, Sareen Fiaz, Deirdre C. Lyons

Landscape and regulation of new protein translation in the early C. elegans embryo

Yash Shukla, Vighnesh Ghatpande, Cindy F. Hu, Daniel J. Dickinson, Can Cenik

A complete collagen IV fluorophore knock-in toolkit reveals α-chain diversity in basement membrane

Sandhya Srinivasan, Willam Ramos-Lewis, Mychel R.P.T. Morais, Qiuyi Chi, Adam W. J. Soh, Emily Williams, Rachel Lennon, David R. Sherwood

Bovine endometrial organoids: A new tool to study conceptus-maternal interactions in mammals

Jessica C. Edge, Olga Amelkina, Haidee Tinning, Gianluca Giovanardi, Elena Mancinelli, Samantha Gardner, Elton JR Vasconcelos, Virginia Pensabene, Karen Forbes, Mary J O’Connell, Peter Ruane, Niamh Forde

A Spatiotemporal Atlas of Mouse Gastrulation and Early Organogenesis to Explore Axial Patterning and Project In Vitro Models onto In Vivo Space

Luke TG Harland, Tim Lohoff, Noushin Koulena, Nico Pierson, Constantin Pape, Farhan Ameen, Jonathan Griffiths, Bart Theeuwes, Nicola K Wilson, Anna Kreshuk, Wolf Reik, Jennifer Nichols, Long Cai, John C Marioni, Berthold Gottgens, Shila Ghazanfar

MSLASpheroidStamp: 3d cell spheroids for everyone

Artem S Minin, Tanya Semerikova, Olga Karavashkova, Varvara Pozdina, Maria Tomilina, Ilya Zubarev, Anna Belousova

Integration of spatial and single nucleus transcriptomics to map gene expression in the developing mouse kidney

Christopher P. Chaney, Alexandria N. Fusco, Elyse D. Grilli, Jane N. Warshaw, Peter M. Luo, Ondine Cleaver, Denise K. Marciano, Thomas J. Carroll

The cell biology and genome of Stentor pyriformis, a giant cell that embeds symbiotic algae in a microtubule meshwork

Vincent Boudreau, Ashley R. Albright, Therese M. Gerbich, Tanner Fadero, Victoria Yan, Ben T. Larson, Aviva Lucas-DeMott, Jay Yung, Solène L.Y. Moulin, Carlos Patiño Descovich, Mark M Slabodnick, Adrien Burlacot, Jeremy R. Wang, Krishna K Niyogi, Wallace F. Marshall

Ilastik: a machine learning image analysis platform to interrogate stem cell fate decisions across multiple vertebrate species

Alma Zuniga Munoz, Kartik Soni, Angela Li, Vedant Lakkundi, Arundati Iyer, Ari Adler, Kathryn Kirkendall, Frank Petrigliano, Bérénice A. Benayoun, Thomas P. Lozito, Albert E. Almada

Spatiotemporal Regulatory Logics of Mouse Gastrulation

Xianfa Yang, Bingbing Xie, Penglei Shen, Yingying Chen, Chunjie Li, Fengxiang Tan, Yumeng Yang, Yun Yang, Rui Song, Panpan Mi, Zhiwen Liu, Mingzhu Wen, Patrick P. L. Tam, Shengbao Suo, Naihe Jing

Cataloguing the postnatal small intestinal transcriptome during the first postnatal month

Luiz Fernando Silva Oliveira, Radhika S. Khetani, Yu-Syuan Wu, Venkata Siva Dasuri, Amanda W. Harrington, Oluwabunmi Olaloye, Jeffrey Goldsmith, David T. Breault, Liza Konnikova, Shannan J. Ho Sui, Amy E. O’Connell

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

Christopher J. Panebianco, Maha Essaidi, Elijah Barnes, Ashley Williams, Karin Vancíková, Margot C. Labberté, Pieter Brama, Niamh C. Nowlan, Joel D. Boerckel

Research practice & education

A scientific case for revisiting the embryonic chicken model in biomedical research

Mike J McGrew, Tana Holmes, Megan G Davey

Reporting quality of quantitative polymerase chain reaction (qPCR) methods in scientific publications

Natascha Drude, Camila Baselly, Małgorzata Anna Gazda, Jan-Niklas May, Lena Tienken, Parya Abbasi, Tracey Weissgerber, Steven Burgess

Leaving Science: Attrition of Biologists in 38 OECD Countries

Marek Kwiek, Lukasz Szymula

ggrain – a ggplot2 extension for raincloud plots

Nicholas Judd, Jordy van Langen, Davide Poggiali, Kirstie Whitaker, Tom Rhys Marshall, Micah Allen, Rogier Kievit

Investing in Open Science: Key Considerations for Funders

Dana E. Cobb-Lewis, Devin Synder, Sonya Dumanis, Robert Thibault, Barbara Marebwa, Elisia Clark, Lara St. Clair, Leslie Kirsch, Michelle Durborow, Ekemini Riley

Building Inclusive Leadership: A Biosciences Approach

Emily May Armstrong, Lydia Bach, Philip Robinson, Helen Walden, Nathan Woodling, Matt Jones

You can do it!–Using published undergraduate research on Hydra mouth opening to train undergraduates

S. Hackler, T. Goel, J. Pacis, E.-M. S. Collins

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Tags: monthly preprints, preprints
Categories: Research

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Most-read posts in December

Behind the paper: “Temporal variability and cell mechanics control robustness in mammalian embryogenesis” by Bernat Corominas-Murtra
Peer review – why we need it and what we need by Katherine Brown
No such thing as a standard career path
The mechanics of crocodile head scale development by Rory L. Cooper, Ebrahim Jahanbakhsh & Michel C. Milinkovitch
Featured Resource: Gene Expression Database (GXD)
Lab meeting with the Hirashima lab

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