From our sister journals- November 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.

Genome-wide lacZ profiling in the mouse

Tuck, Estebel and colleagues have produced an open access adult mouse expression resource with the expression profile of 424 assessed in up to 47 different organs, tissues and substructures using a lacZ reporter gene. Read the paper here [OPEN ACCESS].

A method for labelling leukocytes infiltrating the mouse retina

Sim and colleagues describe a method to image myeloid cells infiltrating the mouse retina in vivo using a depot injection of indocyanine green dye (ICG). Read the paper here [OPEN ACCESS].

Urine-derived stem cells predict patient response to cholesterol-lowering drug

Si-Tayeb, Idriss and colleagues have shown that cells derived from patient urine samples can be reprogrammed to generate patient-specific models of hypercholesterolemia, providing a tool to predict patient response to cholesterol-lowering drugs. Read the paper here [OPEN ACCESS], and read the press release here.

Mass and drought resistance linked in seedlings

Seedlings of large-seeded plants are considered to withstand abiotic stress more efficiently. Meng and colleagues show that the integration of drought stress response into the regulation of mass is mediated by the transcription factor ARF2. Read the paper here.

New role for eIF6 in myofibroblast differentiation

Myofibroblast differentiation is regulated by TGF-β1. In this paper, Yang and colleagues show that eukaryotic initiation factor 6 can modulate myofibroblast differentiation by altering the occupancy of the TGF-β1 promoter by H2A.Z and Sp1, affecting TGF-β1 transcription. Read the paper here.

High-salt exposure increases cardiovascular defects in early chick embryos

In chick, embryonic mortality at early stages is usually due to vascular malformations. Wang and colleagues show that high-salt exposure results in angiogenesis and heart defects, possibly due to excess generation of reactive oxygen species (ROS). Read the paper here.

The effects of rearing amphibious fish out of water

Wells, Turko and Wright rear an amphibious fish in and out of water, and find that embryos reared in aqueous environments consume more energy than their faster developing terrestrial counterparts. Read the paper here.

Hatching success does not decrease with higher nest temperatures in flatback turtles

Elevated nest temperatures caused by climate change could harm the viability of ectotherm eggs. Howard and colleagues show that high nest temperatures do not decrease hatching success in flatback turtles, and observe a high pivotal sex-determining temperature in these turtles. Read the paper here.

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