Senior Bioinformatician

The reNEW Node in Leiden is seeking for a senior bioinformatician in the team of multidisciplinary researchers working on development of stem cell models of human disease. The bioinformatician will support the analysis of bulk and single-cell RNA-seq and spatial transcriptomics datasets generated from human stem cell models and integrating them with primary human datasets. Previous experience with analysis of single-cell datasets and programming experience in Python and R is required. Interest in human pluripotent stem cell biology, developmental biology and cell-lineage specification is an advantage. Ability to work independently and in a team required.

The research environment

The position funded by the reNEW grant will offer the opportunity to work in an interdisciplinary team of researchers of the reNEW Node in Leiden. The project aims to advance modelling disease using stem cells to understand pathogenetic mechanism, validate novel causative genes and screen for lead compounds for the development of novel therapies. You will have access to (and may be inbedded in) the state-of-the-art communing infrastructure at Leiden Genome Technology Center (LGTC) and genomics facilities at the University of Copenhagen (Copenhagen, Denmark) and Murdoch Children’s Research Institute (Melbourne, Australia).

Your profile

You have obtained a PhD degree in Biomedical sciences, Molecular Biology, Biochemistry or a similar field within the last five years. You should be highly motivated, capable of working both independently and in a team. English communications skills are required. The main tasks are as follows:

• Analysis of large datasets, using established or new pipelines, statistical and machine-learning analyses, data visualization, and written & oral reporting to the team of stem cell biologists.
• Producing high quality visualization of data for publications, manuscript preparation and publishing.
• Support junior researchers in the team (PhD students, Postdocs) and provide advice of the experimental design and analysis methods.
• Work independently on several major and minor projects across independent teams of researchers. 

More information

We offer a full-time position based on an 36-hour week. The appointment is initially for one year with the possibility of extension.Your salary will depend on your qualifications and experience, with a minimum of €2,986 and a maximum of  €5,483 gross per month based on a full-time position (scale 10 or 11 of the Collective Labor Agreement for Dutch University Hospitals).