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developmental and stem cell biologists

Zinc Finger Nucleases targeting genes in a frog near you!

Posted by , on 9 May 2011

Loss-of-function studies in Xenopus have been, until recently, limited to transient knockdowns by injection of morpholino antisense oligonucleotides.  In part because of X. laevis’ complex allotetraploid genome, the system lacked ...

The story behind the screen - flashbacks from the first RNAi screen in a whole vertebrate

Posted by , on 9 May 2011

The story of our recently released Development paper ‘FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools’ (http://dev.biologists.org/content/138/10/1893.full) involves hundreds of dozens ...

6th International Chick Conference

Posted by , on 6 May 2011

Can I just bring to eveyone’s attention that the 6th International Chick Conference is now to be held at The Roslin Insititute, UK. Sept 17-20, 2011. This forum often attracts ...

Healing an injured heart

Posted by , on 5 May 2011

Regenerative medicine and stem cell research go hand-in-hand when it comes to dreaming up future strategies for treating disease and injury in humans.  Today’s image is from a recent Development ...

Map of Life: A guide to convergent evolution

Posted by , on 4 May 2011

The Map of Life is a recently published guide to convergent evolution produced by the University of Cambridge that has been touring science festivals and events across the world. It ...

March of Dimes Prize Announced

Posted by , on 4 May 2011

The March of Dimes Prize in Developmental Biology was jointly awarded this April to David Page, Director of the Whitehead Institute, and Patricia Ann Jacobs, professor of human genetics at ...

Second cover image winner: mouse pharyngeal arch

Posted by , on 4 May 2011

Congratulations to Hozana Andrade Castillo of the University of Sao Paulo in Brazil, whose image of a mouse pharyngeal arch jumped from third place to first place in the last ...

An After Thought to Evolution: Exceptional ways of Controlling Gene “Expression”

Posted by , on 3 May 2011

More and more, the central dogma is becoming well, dogged, for being a dogma at all. As humans, we have 3 billion nucleotides. Only 1% of it makes up our ...

Science – The Bigger Picture

Posted by , on 1 May 2011

This is a retelling of the student and post-doc workshop from the second day of the BSDB/BSCB joint spring meeting that took place in Canterbury at the University of Kent. ...

Rethinking X-chromosome Inactivation

Posted by , on 30 April 2011

I’ve been asked to present the back-story behind our recently published manuscript in Development “Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse ...

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