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developmental and stem cell biologists
Posted by the Node Interviews, on 9 April 2018
Cell fate commitment relies on both activation of appropriate genes and suppression of inappropriate ones. Polycomb group proteins are known to be crucial epigenetic silencers of developmental genes, but the ...Posted by Joachim Goedhart, on 5 April 2018
In a previous blog, I have disgraced parrots by associating them with P-values and discrediting them for their mechanic repetition. Nevertheless, I admire the vivid colours of these multifaceted birds. ...Posted by the Node Interviews, on 5 April 2018
Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is ...Posted by the Node, on 4 April 2018
One of the most talked about preprints this month was a corrigendum to that Nature Methods paper reporting widespread off-target mutations following CRISPR-Cas9 editing in mice. The paper was challenged quickly on ...Posted by the Node, on 27 March 2018
This editorial and interview appeared in Development, Vol 145 Issue 6 A new Editor-in-Chief for Development Sarah Bray, Kate Storey, Katherine Brown As many of you will be ...Posted by SRulands, on 23 March 2018
Steffen Rulands and Benjamin Simons A discussion of our recent paper: Rulands S et al., Universality of clone dynamics during tissue development. Nature Physics | doi:10.1038/s41567-018-0055-6 Often, the most ...Posted by Elias Barriga, on 22 March 2018
In these lines I share with you some details of our recently published Nature paper. I will comment how this project was started and details which are not included in ...Posted by the Node, on 20 March 2018
Earlier in the year we and Abcam ran a competition to find a meeting reporter for the upcoming Abcam Adult Neurogenesis meeting to be held in Dresden in May. Today we ...Posted by Elise P., on 19 March 2018
The story behind our paper: Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Carla G. Silva, Elise Peyre, Mohit H. Adhikari, Sylvia Tielens, Sebastian Tanco, Petra Van Damme, Lorenza Magno, ...Posted by Gabriel Aughey, on 13 March 2018
The following post is an introduction into the technnique described in our recent paper: Aughey, G.N., et al., CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in ...