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Postdoc position

Posted by on July 27th, 2020

Open postdoc position! Interested in understanding how stretching affects tissue behaviour? Want to work in a brand new lab in a friendly and supportive environment? Join the Tissue Architecture Lab at the Novo Nordisk Foundation Center for Stem Cell Biology, DanStem at Copenhagen University! Here is the link to the open position https://employment.ku.dk/faculty/?show=152331 and the link[…]

Kink in the road: the notochord’s role in spine formation and scoliosis

Posted by on April 14th, 2020

By Jennifer Bagwell and Michel Bagnat   Our lab investigates the role of hydrostatic pressure as a morphogenetic force using zebrafish as a model system.  This work was originally focused on tube formation and had revealed a crucial role for fluid secretion in single lumen formation (Navis and Bagnat, 2015). When I joined, the lab[…]

The people behind the papers – Daniel Osório, Elaine Chan, Joana Saramago and Ana Carvalho

Posted by on January 13th, 2020

This interview, the 73rd in our series, was recently published in Development.  Animal cytokinesis is driven by an actomyosin ring that assembles at the cell equator and constricts to physically separate the two daughters. Although myosin is known to be essential for cytokinesis in multiple systems, whether this requirement reflects its motor or actin crosslinking activities has[…]

Postdoctoral Position to Study Mechanotransduction in the Heart

Posted by on August 23rd, 2019

The Radice laboratory in the Cardiovascular Research Center (CVRC) (http://cvrc.brownmedicine.org) at Rhode Island Hospital/Brown University is seeking a creative and exceptionally motivated postdoctoral researcher to investigate the mechanistic basis for how heart muscle cells sense and respond to mechanical force. Our current research emphasis is to identify how N-cadherin together with the underlying cytoskeleton transmits[…]

The people behind the papers: Gabriel Krens and Carl-Philipp Heisenberg

Posted by on May 25th, 2017

Cell sorting is a critical process during development, as differently specified cells are segregated to the right parts of the embryo. Differences in cell adhesion and cortical tension are thought to be crucial to this process, but the mechanics have been difficult to probe in vivo. This week’s paper, published in the current issue of[…]

How mechanical signals orchestrate stem cell fate

Posted by on August 23rd, 2016

Controlling differentiation using biophysical cues from development Embryonic stem cells have the potential to become any cell type in the adult organism, but coaxing them to a specific fate continues to be a challenge for researchers. While many of the soluble signals involved in patterning the early embryo are well-established, only recently have tools been[…]

Journey to the East: from San Diego to Singapore

Posted by on July 18th, 2016

Axons in mature nervous systems regenerate poorly after injury, creating a major obstacle for recovery from neuronal injury. We know, however, that their regenerative capabilities are affected by both cell-extrinsic and intrinsic factors. Understanding these processes is crucial to provide future therapeutic intervention for neuronal regeneration. We recently found a cell-intrinsic factor inhibiting axon regeneration[…]