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developmental and stem cell biologists
Posted by the Node Interviews, on 9 April 2018
Cell fate commitment relies on both activation of appropriate genes and suppression of inappropriate ones. Polycomb group proteins are known to be crucial epigenetic silencers of developmental genes, but the ...Posted by Seema Grewal, on 24 May 2011
Here are the highlights from the current issue of Development: How transcriptional silencing goes into reverse The Polycomb group (PcG) machinery silences terminal differentiation genes in stem cell lineages. Reversal ...Posted by Seema Grewal, on 7 December 2010
The first issue of 2011 is out now…here are the highlights: Geminin control of lineage commitment The transition between pluripotency and multi-lineage commitment during early embryogenesis must be closely regulated ...Posted by Seema Grewal, on 13 July 2010
Here are the research highlights from the new issue of Development… TORc1-ing about stem cell differentiation In adult tissues, the tight regulation of stem cell selfrenewal and differentiation maintains tissue ...