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BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Matyas Bubna

Posted by on January 19th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Genomic Analyst position at Xenbase, the Xenopus Model Organism Knowledgebase

Posted by on December 12th, 2019

Xenbase (www.xenbase.org) is the Xenopus bioinformatics and genomics knowledgebase funded by the NIH/NICHHD. We have has two performance sites: the curation team at Cincinnati Children’s, Cincinnati OH (PI: Dr. Aaron Zorn) and the database management team at the University of Calgary in Canada (PI Dr. Peter Vize). Xenbase is seeking to fill 1 full time[…]

Starvation halts brain development, but hungry cells jump-start growth when food becomes available

Posted by on October 25th, 2019

In research that holds potential for prenatal health and brain injury, Scripps Research scientists identify cellular workings that stop and restart early brain development. Press release from Scripps Research, La Jolla.  We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly[…]

The people behind the papers – Joe Shawky & Lance Davidson

Posted by on October 24th, 2018

The construction of complex three-dimensional tissue structures during embryogenesis requires precise control of cell and tissue mechanics. The Xenopus embryo provides a powerful tool for interrogating this relationship, as demonstrated by a recent Development paper reporting the use of tissue explants to test predictions of mechanical models. We caught up with first author and recent graduate Joseph[…]

The people behind the papers – Anjali Rao & Carole LaBonne

Posted by on August 9th, 2018

The neural crest is a progenitor population with the capacity to contribute to all vertebrate germ layers. The transcription factor and signalling pathway activity underlying this remarkable pluripotency have been well studied, but the role of the epigenetic state is less well understood. A new paper in Development examines the role of histone acetylation in regulating[…]

The people behind the papers – Martina Nagel & Rudolf Winklbauer

Posted by on July 6th, 2018

Contact inhibition of locomotion is a widespread phenomenon in migrating cells. However, cells often migrate collectively as a sheet, raising the question of how contact inhibition is overcome in these scenarios. A new paper in Development addresses this problem by studying the signals that regulate collective migration in Xenopus leading edge mesendoderm (LEM) cells. We[…]

Mechanical cues as developmental pacers that orchestrate morphogenesis

Posted by on March 22nd, 2018

In these lines I share with you some details of our recently published Nature paper. I will comment how this project was started and details which are not included in the manuscript. Finally, I will briefly comment on some questions we are working on today and others we believe are worth addressing in the future.[…]

This year for Christmas, gift yourself with an amazing experience. Apply today for the 2018 CSHL Cell and Developmental Biology of Xenopus course.

Posted by on December 18th, 2017

The end of the year is quickly approaching, and if you are anything like me you are scrambling to try to get as much work done as possible before your holiday break. But while this frequently entails getting papers submitted, committee meetings completed, and experiments wrapped up, I also take the opportunity to reflect on[…]

What Illustrators See that a Camera Can’t

Posted by on August 29th, 2017

Illustrator Natalya Zahn on the role of observation and visual interpretation in her work creating an addendum to Nieuwkoop and Faber’s classic Normal Table of Xenopus laevis   As an artist of science and nature subjects, I’m often asked what makes the work I do better than a photograph. It makes perfect sense to imagine that a[…]

Biocurator position at Xenbase

Posted by on August 9th, 2017

Curator position at Xenbase, the Xenopus Model Organism database Xenbase (www.xenbase.org) is the Xenopus bioinformatics and genomics resource. Xenopus is a major model for fundamental cell and developmental biology and a model for human disease. Xenbase is a totally free, and globally accessible database, used by Xenopus researchers worldwide, and is funded by the National[…]