the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by the Node on November 12th, 2020
Yesterday we held the second webinar in our new series, this time coinciding with the publication of our Special Issue on The Origins and Mechanisms of Developmental Disorders and featuring three fantastic talks on the theme. Here you’ll find the three talks and their live Q&A sessions, moderated by John Wallingford, one of the guest[…]
Posted by Anna Philpott on August 26th, 2020
A postdoctoral Research Associate position is currently available for an individual to work in the laboratory of Prof. Anna Philpott within the Cambridge Stem Cell Institute (https://www.stemcells.cam.ac.uk/research/pis/philpott). The Philpott lab has broad interests in understanding the fundamental mechanisms that determine cell fate choice and differentiation during embryonic development and in cancers, as well as how[…]
Posted by BSDB on January 19th, 2020
Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]
Posted by Xenopus2 on December 12th, 2019
Xenbase (www.xenbase.org) is the Xenopus bioinformatics and genomics knowledgebase funded by the NIH/NICHHD. We have has two performance sites: the curation team at Cincinnati Children’s, Cincinnati OH (PI: Dr. Aaron Zorn) and the database management team at the University of Calgary in Canada (PI Dr. Peter Vize). Xenbase is seeking to fill 1 full time[…]
Posted by the Node on October 25th, 2019
In research that holds potential for prenatal health and brain injury, Scripps Research scientists identify cellular workings that stop and restart early brain development. Press release from Scripps Research, La Jolla. We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly[…]
Posted by the Node Interviews on October 24th, 2018
The construction of complex three-dimensional tissue structures during embryogenesis requires precise control of cell and tissue mechanics. The Xenopus embryo provides a powerful tool for interrogating this relationship, as demonstrated by a recent Development paper reporting the use of tissue explants to test predictions of mechanical models. We caught up with first author and recent graduate Joseph[…]
Posted by the Node Interviews on August 9th, 2018
The neural crest is a progenitor population with the capacity to contribute to all vertebrate germ layers. The transcription factor and signalling pathway activity underlying this remarkable pluripotency have been well studied, but the role of the epigenetic state is less well understood. A new paper in Development examines the role of histone acetylation in regulating[…]
Posted by the Node Interviews on July 6th, 2018
Contact inhibition of locomotion is a widespread phenomenon in migrating cells. However, cells often migrate collectively as a sheet, raising the question of how contact inhibition is overcome in these scenarios. A new paper in Development addresses this problem by studying the signals that regulate collective migration in Xenopus leading edge mesendoderm (LEM) cells. We[…]
Posted by Elias H Barriga on March 22nd, 2018
In these lines I share with you some details of our recently published Nature paper. I will comment how this project was started and details which are not included in the manuscript. Finally, I will briefly comment on some questions we are working on today and others we believe are worth addressing in the future.[…]
Posted by Heather Ray on December 18th, 2017
The end of the year is quickly approaching, and if you are anything like me you are scrambling to try to get as much work done as possible before your holiday break. But while this frequently entails getting papers submitted, committee meetings completed, and experiments wrapped up, I also take the opportunity to reflect on[…]
