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MCC loss during mucociliary epithelium remodeling: new insight into a debated topic and a decade mystery.

Posted by , on 29 March 2021

Introduction In mucociliary epithelia, such as the mammalian airway epithelium or the embryonic epidermis of Xenopus tadpoles, the correct balance between multiciliated cells (MCCs) and secretory cells provides the functional ...
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Development presents... November webinar videos

Posted by , on 12 November 2020

Yesterday we held the second webinar in our new series, this time coinciding with the publication of our Special Issue on The Origins and Mechanisms of Developmental Disorders and featuring ...
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Transcriptional Regulation of Stem Cell Fate-postdoctoral position Philpott lab

Posted by , on 26 August 2020

A postdoctoral Research Associate position is currently available for an individual to work in the laboratory of Prof. Anna Philpott within the Cambridge Stem Cell Institute (https://www.stemcells.cam.ac.uk/research/pis/philpott). The Philpott lab ...
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BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report - Matyas Bubna

Posted by , on 19 January 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage ...
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Genomic Analyst position at Xenbase, the Xenopus Model Organism Knowledgebase

Posted by , on 12 December 2019

Xenbase (www.xenbase.org) is the Xenopus bioinformatics and genomics knowledgebase funded by the NIH/NICHHD. We have has two performance sites: the curation team at Cincinnati Children’s, Cincinnati OH (PI: Dr. Aaron ...
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Starvation halts brain development, but hungry cells jump-start growth when food becomes available

Posted by , on 25 October 2019

In research that holds potential for prenatal health and brain injury, Scripps Research scientists identify cellular workings that stop and restart early brain development. Press release from Scripps Research, La ...
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The people behind the papers - Joe Shawky & Lance Davidson

Posted by , on 24 October 2018

The construction of complex three-dimensional tissue structures during embryogenesis requires precise control of cell and tissue mechanics. The Xenopus embryo provides a powerful tool for interrogating this relationship, as demonstrated ...
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The people behind the papers - Anjali Rao & Carole LaBonne

Posted by , on 9 August 2018

The neural crest is a progenitor population with the capacity to contribute to all vertebrate germ layers. The transcription factor and signalling pathway activity underlying this remarkable pluripotency have been well ...
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The people behind the papers - Martina Nagel & Rudolf Winklbauer

Posted by , on 6 July 2018

Contact inhibition of locomotion is a widespread phenomenon in migrating cells. However, cells often migrate collectively as a sheet, raising the question of how contact inhibition is overcome in these ...
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Mechanical cues as developmental pacers that orchestrate morphogenesis

Posted by , on 22 March 2018

In these lines I share with you some details of our recently published Nature paper. I will comment how this project was started and details which are not included in ...
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