the community site for and by developmental biologists

New DMDD embryonic-lethal mouse data now available

Posted by on August 15th, 2016

  This post was originally posted on the DMDD blog.   New embryonic-lethal knockout mouse lines are now available on the DMDD database. If you haven’t previously taken a look at our data (or even if you have) now would be a good time to explore our website.  We’ve added new embryo phenotype data and[…]

Postdoc in Bioinformatics

Posted by on August 12th, 2016

A postdoctoral position is available for a bioinformatician to investigate the mechanisms by which microRNAs, transcription factors and developmental signals control skeletal and cardiac muscle differentiation. The post is based in the School of Biological Sciences at the University of East Anglia, Norwich, in the group headed by Professor Andrea Münsterberg. Their research aims to[…]

A new role of an insect steroid hormone: The link between mating and germline stem cells

Posted by on August 11th, 2016

Tomotsune Ameku, Ryusuke Niwa’s lab, University of Tsukuba, Japan.   Steroid hormones have crucial roles in regulating a broad range of biological processes in most multicellular organisms. They are produced in specialized endocrine organs and act as ligands for the nuclear receptor family of transcription factors. In mammals, sex steroid hormones, such as estrogen and[…]

How many and which genes for multicellularity?

Posted by on August 9th, 2016

My research interest is the evolution of multicellularity. How did cells ‘learn’ to communicate with each other to build a structure that is more complex than its parts and shows new emergent behaviour? Which and how many new genes would be required to transform a unicellular ancestor into a well-organised multicellular structure? The Nature Communications[…]

Lab Manager Position (50% employment)

Posted by on August 3rd, 2016

The Laboratory of Regulatory Evolution (Tschopp group) at the Zoological Institute, University of Basel, Switzerland, is hiring for a lab manager position. We are interested in how phenotypic diversity is generated during vertebrate embryogenesis. As a model system, we are studying the development of the vertebrate skeleton with its associated neuromuscular system. We address these[…]

Multiple PhD Positions in Biology, Biochemistry and Bioinformatics

Posted by on August 2nd, 2016

The Fribourg Graduate School of Life Sciences (FGLS) is an interdisciplinary and international graduate school, which offers a coordinated doctoral programme in life sciences at the University of Fribourg. It addresses doctoral fellows in the fields of biology, biochemistry, molecular medicine, chemistry, physics, bioinformatics and mathematics who have a life science focus. State-of-the-art theoretical and[…]

In Development this week (Vol. 143, Issue 15)

Posted by on August 2nd, 2016

Here are the highlights from the current issue of Development:   Defining Polycomb complexes with AEBP2 Polycomb repressive complex 2 (PRC2) directs methylation of histone H3 K27 (H3K27me), a repressive histone mark. Mutations in PRC2 complex components cause a spectrum of developmental defects, including posterior transformation of the skeleton due to misexpression of Hox cluster[…]

Two PhD positions in Regulatory Evolution, Tschopp group, University of Basel, Switzerland

Posted by on August 1st, 2016

The Laboratory of Regulatory Evolution (Tschopp group) at the Zoological Institute, University of Basel, is hiring for two fully funded PhD positions. Our research interests focus on two main questions: 1. How is phenotypic diversity generated during vertebrate embryogenesis? And 2. how can developmental processes be modified to drive morphological evolution? We are particularly interested[…]

MBL Embryology Course 2016

Posted by on August 1st, 2016

“My dear, here we must run as fast as we can, just to stay in place. And if you wish to go anywhere you must run twice as fast as that.” L. Carroll ‘Alice Through the Looking Glass’   We write this while we finish the last experiments for the final Show n’ Tell on[…]

July in preprints

Posted by on August 1st, 2016

Our latest monthly trawl for preprints. See June’s post for background, and let us know if we missed anything This month we found preprints on various themes in developmental biology, as well as a lot of work that we hope will be of general interest to the community. One of July’s most talked-about preprints tackled a subject felt keenly by most scientists,[…]