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Using the mouse to model human disease: increasing validity and reproducibility

Posted by , on 3 February 2016

This editorial by Monica J. Justice and Paraminder Dhillon was first published in Disease Models & Mechanisms.   ABSTRACT Experiments that use the mouse as a model for disease have recently ...
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In Development this week (Vol. 143, Issue 3 )

Posted by , on 2 February 2016

Here are the highlights from the current issue of Development:   New insights into human neural crest induction Human neural crest (NC) cells are the precursors for a wide range ...
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From our sister journals- January 2016

Posted by , on 26 January 2016

Here is some developmental biology-related content from other journals published by The Company of Biologists.     Characterisation of Slc9a6 knockout heterozygous female mice Mutations in SLC9A6 are responsible for X-linked Christianson ...
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Natural Pluripotency vs. Artificial Pluripotency

Posted by , on 20 January 2016

Pluripotency is the developmental potential of cells to become various types of mature cells in the body. During development, a pluripotent embryo progressively differentiates to give rise to mature cell ...
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In Development this week (Vol. 143, Issue 2)

Posted by , on 20 January 2016

Here are the highlights from the current issue of Development:   Fishing out a role for Caveolin 1 in heart regeneration Unlike the adult mammalian heart, the adult zebrafish heart ...
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Regeneration thwarts ageing in newts

Posted by , on 17 January 2016

Konstantinos Sousounis and Panagiotis A. Tsonis   The human eye is built to deliver the sense of vision. The eye lens is one of the organs playing role in focusing ...
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In Memory of Marcos Vidal (1974-2016)

Posted by , on 13 January 2016

This obituary was written by Ross Cagan and Eyal Gottlieb, and first appeared in Disease Models & Mechanisms.   With the untimely death of Marcos Vidal, we have lost a good friend and a ...
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Forgotten classics- Cell layers in the shoot meristem

Posted by , on 12 January 2016

  Satina, S., Blakeslee, A.F., and Avery, A.G. (1940) Demonstration of the Three Germ Layers in the Shoot Apex of Datura by Means of Induced Polyploidy in Periclinal Chimeras. American ...
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Forgotten classics of developmental biology- a new Node series

Posted by , on 12 January 2016

You just started your research career, or maybe you just moved fields. The first thing on your to-do list is to catch up with the literature. What has been the ...
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Applying tandem timers to measure signalling and gene expression dynamics in developing embryos

Posted by , on 11 January 2016

The signalling systems that conduct the orchestra of embryonic development are fantastically complex and dynamic. We owe much of our knowledge of in vivo signalling dynamics to advances in microscopy ...
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