the community site for developmental biologists

Displaying posts in the category: Resources [Clear Filter]

Life’s Blueprint website

Posted by on January 5th, 2015

Dear Colleagues, I recently published a popular book presenting the concepts of embryonic development (Life’s Blueprint: The science and art of embryo creation) at Yale University Press. In addition to the text, I tried to convey the concepts of embryonic development by presenting pairs of images, where one portrays a biological example and the other[…]

Why Not Publish Your Antibody Validation Data

Posted by on December 15th, 2014

Antibodies are frequently used in developmental biology labs, but their validation is crucial to provide the information needed in order to reliably interpret the results of experiments. Antibody validation is also important to help scientists chose antibodies that will be suitable for their experiments, yet the results of these validations rarely get published. To try[…]

Left-right asymmetry, embryonic development, and more

Posted by on August 26th, 2014

Hello there, first time posting on The Node! Every so often Wiley compiles a small selection of recent research on a particular topic, and the most recent is on the topic of developmental biology. This includes some special issues from journals with reviews on: Left-Right asymmetry Embryonic development Cell proliferation and development The first two special[…]

Accelerated Frogs: Developmental Biology meets Particle Physics

Posted by on August 20th, 2014

I previously wrote a post about the development of a 4-D X-Ray Tomography technique for imaging early Xenopus embryos. Frog embryos are opaque due to their yolky composition and this has proved a challenge for traditional optical microscopy of events in the early stages of Xenopus embryo development. However Julian Moosmann, Ralf Hofmann and Jubin[…]

Creative morphometrics – so many tools, so little time

Posted by on August 4th, 2014

Nowadays, the hardest thing in science is similar to what we experience in daily life, that is organization and choice. In a virtual plethora of techniques, methods and analyses, an aspiring researcher is faced with a flood of information, achievements and tools of the trade. Especially so with computers. But if it wasn’t for this[…]

Bioimage Analysis 2014 at EMBL, a recap.

Posted by on June 18th, 2014

Last month 39 people from around the world gathered together in the flagship European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany to take part in the Master Course on Bioimage Data Analysis. This was the third edition of the course that had previously been held in Heidelberg and Barcelona, and is aimed at training scientists[…]

Giving scientific ideas a voice (and a video)

Posted by on May 20th, 2014

Explaining new scientific concepts can be a daunting task for anyone involved in outreach. We are constantly trying to come up with ways to explain, show and describe theories and ideas step by step. I’ve recently stumbled across a new app (albeit only available on ipad) called Adobe Voice that could help out scientific communication.[…]

Outreach Activity – Smartphone to Microscope Conversion

Posted by on May 6th, 2014

Development is a fascinating process that few people have a chance to see, let alone photograph! We recently participated with other scientists from the Crick Institute at a Science Museum Lates in London in February. For our activity, we built these inexpensive platforms that convert a user’s smartphone into a microscope screen. We provided zebrafish[…]

Flippase recognition target: orientation matters, so why care?

Posted by on April 16th, 2014

FRT sites are used often (at least in Drosophila) for inducing deletions or “flipping out” of markers in transgenic constructs. When there are two FRTs sequences in tandem, after inducing flippase the DNA sequence that is between these two sites will be deleted. If two FRT sites are facing each other (or looking away), the[…]

Mapping the Embryo for Developmental Biologists & Stem Cell Researchers; LifeMap Discovery® – a Roadmap of Mammalian Cell Ontology

Posted by on March 30th, 2014

Understanding how cells differentiate during embryonic development is invaluable for the in vitro derivation of functional cells from stem cells. However, mapping the human embryo, including characterization of all the cell types that make up the developing and mature human body, and of all embryonic progenitor cell types that appear in intermediate developmental stages, is[…]