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Research Highlight: Understanding the Key Role of a EMT Master Regulator, Twist1, during Mouse NCC Delamination and EMT.

Posted by , on 11 July 2022

Epithelial to mesenchymal transition (EMT) is an essential process in multiple steps of embryogenic morphogenesis and various pathological conditions. As an example, EMT is involved in gastrulation and neural crest ...
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Genes activated in metastasis also drive the first stages of tumour growth

Posted by , on 19 February 2018

In spite of the difference between the cell functions responsible for giving rise to a tumour and for the metastasis of this same tumour, studies at IRB Barcelona using the ...
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The right information

Posted by , on 19 October 2017

Oscar H. Ocaña and M. Angela Nieto Comment on “A right-handed signalling pathway drives heart looping in vertebrates”. Nature 549, 86-90 (2017).   A fundamental aspect of vertebrates is their ...
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A Crumby affair: Cell ingression during gastrulation

Posted by , on 31 January 2017

Comment on “Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation” Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV. Nat Cell Biol. 2016 Dec;18(12):1281-1291   “It is not birth, marriage, or ...
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How mechanical signals orchestrate stem cell fate

Posted by , on 23 August 2016

Controlling differentiation using biophysical cues from development Embryonic stem cells have the potential to become any cell type in the adult organism, but coaxing them to a specific fate continues ...
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From our sister journals- February 2016

Posted by , on 22 February 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Using the developmental biology toolkit to study cancer Aiello ...
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The 7th International EMT Meeting (Oct. 11-14, 2015; Melbourne, Australia)

Posted by , on 21 April 2015

The 7th International EMT Meeting will be held in Melbourne, Australia in October 2015. The meeting has been a key venue for bringing together developmental, cell and cancer biologists and ...
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Gastrulation: Local actions, global movements and self-organisation

Posted by , on 6 June 2014

Cells move in (still) mysterious ways to achieve morphogenesis. Prominently, cells of an early vertebrate embryo (blastula, a mass of undifferentiated cells) move extensively during gastrulation to generate the three ...
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