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Displaying posts with the tag: germline-stem-cells [Clear Filter]

A day in the life of a modern Lernaean Hydra…

Posted by on July 3rd, 2017

I am Eleni Chrysostomou, a PhD student in Uri Frank‘s lab at the National University of Ireland, Galway. The Frank lab’s general interest is development and regeneration, stem and germ cell biology, neural fate commitment, and the chromatin biology underlying these processes. The focus of my project is the roles of SoxB transcription factors (TFs)[…]

It’s decision time!

Posted by on May 27th, 2014

Decisions, decisions…aren’t those one of our main worries? It is certainly the everyday worry of a stem cell! Understanding stem cell decisions is a central question in the field: how do stem cells manage to keep the right balance between self-renewal (make identical copies of themselves) and differentiation (produce specialized cells)? How do stem cells[…]

Stem cell success is team work!

Posted by on September 17th, 2013

    Stem cell beauty…yes they are so beautiful, they have amazing properties, they bring a lot of hope for future therapies…well, yes they are the stars! However, like in everyday life, “the star” is not the only one to be the key of its own success, success is teamwork! And for stem cells, the[…]

Don’t get rid of the middleman

Posted by on December 12th, 2012

There are a lot of situations in life where the “middleman” is unnecessary and costly.  In cells, that middleman is necessary and fascinating at the same time.  The sequence of DNA to middleman mRNA to protein provides our cells with countless ways to regulate complex events, including those surrounding stem cell divisions. When stem cells[…]

In Development this week (Vol. 138, Issue 16)

Posted by on July 26th, 2011

Here are the research highlights from the current issue of Development: Pushing the nuclear envelope Not all nuclei are regular spheres as is often shown in textbooks. For example, in Drosophila embryos, nuclei are initially spherical but they elongate and acquire an irregular lobulated morphology during cellularisation. These morphological changes coincide with transcriptional activation of[…]