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Displaying posts with the tag: haematopoietic-stem-cells [Clear Filter]

Where does blood come from in the first place and how is it made?

Posted by on September 14th, 2016

Commentary on Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells in Developmental Cell, Volume 38, Issue 4, p358–370, 22 August 2016   Each of us has around 6 pints of blood. The blood contains a number of different types of cells, including oxygen-transporting red blood cells, disease-protecting white[…]

The origin of blood

Posted by on September 4th, 2014

As for the origin of species, the question of the origin of blood during development has unleashed a lot of passion among the scientific community. As a matter of fact, the failure to derive blood stem cells (haematopoietic stem cells, HSCs) from pluripotent stem cells (stem cells that can generate any type of cells) has[…]

Challenging an old stem cell dogma

Posted by on August 4th, 2014

Science teachers usually say that science progresses by challenging old dogmas. In the stem cell field, there is a dogma saying that some blood stem cells in the bone marrow stay quiescent (do not divide) for long periods of time. This way, they avoid DNA damage and malignant mutations that could arise during DNA replication[…]

Conference announcement: Advances in stem cell research: Development, Regeneration & Disease in Paris, France

Posted by on January 19th, 2011

Announcement for the Advances in stem cell research: Development, Regeneration & Disease conference at the Pasteur Institute, Paris, April 6-8, 2011.

In the new issue of Development, 137 (17)…

Posted by on August 10th, 2010

The Bicoid gradient, epigenetic control of BMP signalling, haematopoietic stem cells and more…here are the highlights from the current issue of Development: The Bicoid gradient gets into shape without nuclei Morphogen gradients provide key positional information during embryogenesis but how they are established is not well understood. A gradient of the transcription factor Bicoid is[…]