April 2019 - the Node

Post-doc position at the NIH: New mechanisms of WNT/R-spondin signaling in development and stem cells

Posted by alebensohn on April 30th, 2019

Position Description: We seek highly motivated post-doctoral Fellows interested in cell signaling at the intersection of development, stem cells and cancer. Candidates will join the group of Dr. Andres Lebensohn, an Earl Stadtman Principal Investigator in the Laboratory of Cellular and Molecular Biology (LCMB) at the Center for Cancer Research (CCR) of the National Cancer Institute[…]

Forces maintain order between cells

Posted by boudaoud on April 30th, 2019

Written by Antoine Fruleux and Arezki Boudaoud As Lewis Wolpert put it (Wolpert, PLoS Biology 2010), if you extend your two arms, you will likely find that they match in length by better than 0.2%, though they do not seem to directly communicate during their development and growth. Similarly, flowers in an individual plant are[…]

PhD position: Evolutionary origin of synaptic proteins at the Sars Centre in Bergen, Norway

Posted by Burkhardt Group on April 30th, 2019

PhD position There is a vacancy for a 4-year PhD student position at the Sars International Centre for Marine Molecular Biology in the research group of Dr. Pawel Burkhardt (www.sars.no). The position is funded by Sars Centre core funding. The Sars Centre belongs to the University of Bergen and is partner of the European Molecular[…]

Postdoctoral Position in Shark EvoDevo, Stem Cell Biology and Tooth Regeneration

Posted by GJFraser on April 29th, 2019

A postdoctoral position is available in the Laboratory of Gareth Fraser (www.fraser-lab.net) at the Department of Biology, University of Florida. Our lab is focused on a range of research projects based around the central theme of vertebrate evolutionary developmental biology – they include tooth development and regeneration, craniofacial diversity, EvoDevOmics, and skin appendage evolution and development. We are looking for a motivated[…]

Postdoctoral Fellow in Neurodevelopment

Posted by Sara Wilson on April 29th, 2019

Applications are invited from highly motivated individuals who are interested in fundamental mechanisms of neurodevelopment and neurogenetic disorders. The focus of the project is to understand neural developmental and neurological phenotypes in mouse models ofTuberous Sclerosis Complex.The fellowship is in the laboratories of Sara Wilson at the Department of Integrative Medical Biology (IMB), and Leif Carlsson[…]

Meeting report: “Chromatin-based regulation of development”, an excellent Workshop by the Company of Biologists

Posted by RoelNeijts on April 26th, 2019

How can a genome’s cis-regulatory potential drive robust gene expression throughout embryonic development? Do topologically associating domains (TADs) truly contribute to gene expression by spatially constraining the regulatory actions of cis-sequences? And might phase separation by multi-valent proteins also be involved in the regulation of genes and genomic regions? The recent Company of Biologists Workshop on[…]

Image competition: a new developmental biology calendar

Posted by the Node on April 25th, 2019

Have you got a beautiful image of a developing organism you’d like to share with the world? Or a striking computer generated visualisation, or even something you’ve drawn or painted or stitched or crafted? We’re planning a Node calendar for the academic year 2019-20, and want to fill it with your images. Entering is[…]

Functional interrogation of the C-terminal domain of RNA polymerase II in fruit flies

Posted by feiyue.lu92 on April 24th, 2019

Feiyue Lu and David Gilmour tell the story behind their recent paper in Molecular Cell RNA polymerase II (Pol II) is the enzyme responsible for transcribing most genes in eukaryotes. The C-terminal domain (CTD) is a highly repetitive, unstructured domain on the largest Pol II subunit, Rpb1. It consists of numerous repeats of seven amino acids[…]

A Madrid-Washington synergy for mouse embryo live-imaging

Posted by MiquelSendra on April 23rd, 2019

One of the things I learned during my stay in another lab is that you can’t succeed completely by yourself. You can try, sure, but a relevant unanswered question in biology is a hard nut to crack. It usually takes a multidisciplinary approach and great ideas coming from more than one brain. Collaborations are key[…]

Post-doctoral Fellow in Pluripotent Stem Cells and Joint Tissue Development

Posted by aprilcraft on April 23rd, 2019

The Craft lab at Boston Children’s Hospital and Harvard Medical School is looking for an outstanding, highly motivated postdoctoral fellow to join our developmental biology and pluripotent stem cell-based team. We established directed differentiation protocols to generate distinct articular and growth plate-like cartilage lineages from human and mouse pluripotent stem cells (Craft et al., Development[…]