The community site for and by
developmental and stem cell biologists

Behind the paper stories

Behind the paper stories

Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you’ll discover the highs and the lows, the chance encounters and life changing discoveries from the breadth of developmental biology and stem cell research.

Recent posts

A domino effect on brain developmental evolution

Posted by , on 6 December 2019

The discipline “Evo-devo” studies the developmental basis of morphological evolution. In the field, some original animal models are emerging as interesting model organisms, enriching the knowledge in the field more …

How do new cell types evolve? Sea urchins show the way….

Posted by , on 21 November 2019

We know surprisingly little about how evolution has created new cell types. One of the best examples of a recently evolved cell type comes from early sea urchin development. Most …

A biology-modeling crosstalk to uncover feather pattern evolution

Posted by , on 20 November 2019

Richard Bailleul, Jonathan Touboul and Marie Manceau   Patterning in question: 60 years of mathematical and biological studies The coat of Vertebrates displays a stunning diversity of motifs created by …

How do cells know their future and forget their past

Posted by , on 7 November 2019

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’. Now, researchers from the University …

Secret talk between epithelium and endothelium determines hair follicle stem cell fate

Posted by , on 6 November 2019

By Kefei Nina Li and Prachi Jain   Stem cells are typically defined by their ability to self-renew and differentiate. These activities are tightly controlled by both intrinsic cues and …

“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)

Posted by , on 28 October 2019

A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one …

A gnawing question: which cells are responsible for tooth renewal and regeneration?

Posted by , on 23 October 2019

By Amnon Sharir (UCSF), Allon M Klein (HMS), Ophir D Klein (UCSF) As most mouse geneticists know, treating a rodent with malocclusion of its front teeth can be a Sisyphean task: …

The serpent’s maw: mouth function and the dynamics of Hydra regeneration

Posted by , on 30 September 2019

One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does …

“If you notice something unusual in your experiments, don’t just throw it away!”

Read Laura Pellegrini’s piece on choroid plexus organoids 

Do you have a story to tell? We can give comments on drafts and any level of editing you want, and we particularly encourage contributions from researchers for whom English is not their first language.

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Our full archive going back to 2010 is filterable by category, tag and date.

Updated on 21 March 2024