The community site for and by
developmental and stem cell biologists

Behind the paper stories

Behind the paper stories

Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you’ll discover the highs and the lows, the chance encounters and life changing discoveries from the breadth of developmental biology and stem cell research.

Recent posts

Tensed beginnings: how membrane tension gates early differentiation

Posted by , on 9 June 2021

Mouse Embryonic Stem Cells (ES cells) have the capacity to generate any tissue in the organism; this remarkable ability is called naïve pluripotency. Intriguingly, when ES cells start to differentiate …

When statistical physics meets developmental biology: Predicting the structural properties of embryonic tissues from a simple cell parameter

Posted by , on 7 May 2021

By Bernat Corominas-Murtra and Nicoletta I. Petridou Embryo morphogenesis is a play whose outcome is the result of a complex and delicate plot, made of balances and agreements among many …

Continuous and Extended Ex Utero Embryogenesis in Mammals

Posted by , on 6 May 2021

Alejandro Aguilera Castrejon and Jacob Hanna on how to culture mouse embryos for longer

New strings for the puppeteer of evolution

Posted by , on 30 April 2021

Sarah Jacquelyn Smith, Lance Davidson and Mark Rebeiz share the story of their recent paper on the evolution of morphological novelties.

Out on a Flimb or: How I Learned to Stop Worrying and Trust the Mapping

Posted by , on 20 April 2021

Brent Hawkins recalls how mapping the zebrafish rephraim mutation brought insights into the fin-to-limb transition

MCC loss during mucociliary epithelium remodeling: new insight into a debated topic and a decade mystery.

Posted by , on 29 March 2021

Introduction In mucociliary epithelia, such as the mammalian airway epithelium or the embryonic epidermis of Xenopus tadpoles, the correct balance between multiciliated cells (MCCs) and secretory cells provides the functional …

Is it in yet? How the direct transdifferentiation of glia-to-neurons ensures nimble male mating

Posted by , on 25 March 2021

Rachel Bonnington, Carla Lloret Fernández and Laura Molina García tell a tale of transdifferentiation

Reshaping morphogen gradients, one miRNA at a time

Posted by , on 15 March 2021

Jacqueline Copeland and Marcos Simoes-Costa Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA The neural crest has long been referred to as “the fourth germ layer” for …

“If you notice something unusual in your experiments, don’t just throw it away!”

Read Laura Pellegrini’s piece on choroid plexus organoids 

Do you have a story to tell? We can give comments on drafts and any level of editing you want, and we particularly encourage contributions from researchers for whom English is not their first language.

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Our full archive going back to 2010 is filterable by category, tag and date.

Updated on 21 August 2024